Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Chief of Staff

$250k - $275k

Jobleads-US

At Mesh, our mission is to enable consumers to pay and be paid with any asset. Today, trillions of dollars in tokenized assets exist but remain largely unusable for everyday commerce. Mesh is bridging this gap by making crypto payments reliable, useful, and ubiquitous. We combine a powerful orchestration engine with a seamless consumer app to unlock liquidity for the world. Backed by leading investors like SBI, Money Forward, Paradigm, Dragonfly, Galaxy, and PayPal Ventures, we are building the infrastructure for the next era of the global economy. Join us!

Overview Mesh is building the financial operating system that connects exchanges, wallets, and payment flows across the digital asset ecosystem. As we scale, we're looking for a Chief of Staff to be the CEO's closest strategic partner and the executive who makes the company run.

Reporting directly to our Founder and CEO, you'll own how Mesh operates. You'll set the operating rhythm, drive the company's highest-priority initiatives, oversee the Business Operations function, and build Mesh's M&A and Corporate Development function from the ground up. You'll extend the CEO's reach across the company, turning strategy into plans, plans into accountable owners, and owners into results. This is an executive seat on the leadership team: you'll own outcomes, not just coordinate them, and you'll be the person who sources, negotiates, and closes the deals that expand Mesh's reach across crypto and payments.

What You'll Do

Act as the CEO's strategic thinking partner on company priorities, key decisions, and tradeoffs, and represent the CEO with the exec team, board, partners, and investors

Own Mesh's operating rhythm: annual and quarterly planning, OKRs, weekly leadership reviews, exec meetings, and town halls, so priorities are clear, progress is visible, and decisions don't stall

Lead board and investor readiness, including quarterly board updates, exec summaries, and company performance reporting built on a single source of truth for key metrics

Oversee the Business Operations function, partnering with the Biz Ops lead to set priorities, remove blockers, and raise the bar for how cross-functional work is scoped, run, and measured

Drive CEO special projects end to end, from new markets and strategic partnerships (exchanges, wallets, on/off-ramp partners) to pricing and unit economics

Hold the executive team accountable to company goals, surface risks early, and resolve the cross-functional issues that sit between teams

Partner with People on org design, executive hiring, internal communications, and culture

Build the systems, dashboards, and AI-powered workflows that make company performance easy to see and let Mesh scale efficiently

Who You Are

10+ years of experience, including senior leadership in strategy and operations, business operations, corporate development, or as a Chief of Staff to a CEO at a high-growth company

A proven leader who has built a function from scratch, including hiring and managing the team

Has owned (not just supported) a company operating cadence: planning, OKRs, exec reviews, and board preparation at a scaling startup

Executive presence and sound judgment; trusted by the CEO, board, and exec team, and comfortable giving direct feedback upward

Exceptional written and verbal communicator who can turn complexity into clear narratives for the board, leadership, and the whole company

Data-driven and commercially minded; comfortable building models and owning company metrics

Deep experience in crypto and/or payments processing (stablecoins, exchanges, wallets, on/off-ramps, card and payment networks, regulatory licensing), with a network across the ecosystem

Experience in high-growth startup environments (Series B and beyond preferred) and able to travel, including internationally

Able to be in the office 3 days a week

The compensation range provided may span multiple career levels and will be narrowed during the interview process based on factors including a candidate's experience, skills, qualifications, and geographic location. For candidates outside of New York or San Francisco, compensation will be adjusted to reflect the applicable market and location-based pay band. The base salary range listed excludes commission (if applicable), equity, and benefits. The pay range represents the minimum and maximum target for new-hire compensation. Actual compensation may vary and may be higher or lower depending on individual circumstances.

Pay Range $250,000 - $275,000 USD

Why You'll Love It Here At Mesh, you're not stepping into a typical role- you're joining a rocket ship in mid-liftoff. You'll tackle complex, meaningful problems that actually move an industry forward, working alongside a sharp, motivated team that moves quickly, collaborates deeply, and expects everyone to operate with ownership. This is the kind of place where you'll see your work ship fast, make real impact, and be able to point to something and say, "I built that." You'll grow fast, level up your skills, and get a front-row seat to how a high-growth company scales from the inside, with competitive comp, solid benefits, and room to stretch your craft all coming standard. If you're energized by building, learning, and shaping something big-this is where you'll want to be.

Employees based in our

San Francisco, New York, and Bangalore

hubs are expected to work from the office at least 40% of the time (approximately two days per week). This expectation may vary slightly depending on role, team, and business needs. Certain roles that require closer cross-functional collaboration or operational support may have additional in-office requirements, which will be discussed during the interview process. Our hybrid approach is designed to balance meaningful in-person collaboration, team building, and real-time decision-making with the flexibility to work remotely. We believe this structure supports strong execution while preserving autonomy and focus time.

How We Care For Our Team We believe great work happens when people feel valued and supported. That starts with competitive salary and equity that grows as you and the company grow, plus comprehensive health coverage for you and your family. We offer unlimited PTO-and we mean it. Take the time you need to recharge and show up at your best.

We're invested in your growth with a dedicated budget for courses, conferences, and certifications. Work from wherever you're most productive with our remote-friendly approach, and count on having the top-tier tools and equipment you need to do exceptional work.

Mesh Pay is committed to equal employment opportunities regardless of race, color, genetic information, creed, religion, sex, sexual orientation, gender identity, lawful alien status, national origin, age, marital status, and non-job related physical or mental disability, or protected veteran status. Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.

#J-18808-Ljbffr
Vacancy posted 4 days ago
Similar jobs that could be interesting for youBased on the Chief of Staff in San Francisco, CA vacancy
  • MKTQ427R52Location: San Francisco, CAWe're looking for a Chief of Staff to the CMO to provide business leadership and establish operational rigor for the Databricks Marketing organization and support our mission to be the leading enterprise Data + AI company. You will... 
    Suggested
    Work at office
    Worldwide

    DataBricks

    San Francisco, CA
    4 days ago
  •  ...between our ambition and our internal operating foundation is widening, and closing it is now a priority. We are looking for a Chief of Staff to work directly with our CEO: to build the systems the company runs on, own the operational details that cannot slip, and grow... 
    Suggested
    Work at office
    Shift work

    BackOps AI

    San Francisco, CA
    1 day ago
  •  ...years running and grown a high-caliber team turning the art of sales into a scalable science. About the Role We’re looking for a Chief of Staff who will operate as a true extension of the CEO. This is a rare opportunity to work directly alongside the CEO and gain an... 
    Suggested

    Nooks

    San Francisco, CA
    3 days ago
  •  ...infrastructure for solo founders. We believe solo founding is different, and we've built the place for it. We're looking for a Chief of Staff to our CEO, Julian Weisser. This is a 16–18 month role with a clear trajectory: prove yourself here, then move onto the investment... 
    Suggested
    Work at office

    Solo Founders

    San Francisco, CA
    2 days ago
  • $325k - $350k

    Location San Francisco, CA On-site, five days a week Employment Type: Full time Department: Office of the CEO Compensation: $325,000-$350,000 annual base salary + meaningful equity About Interface.ai Financial intelligence should be available to everyone. interface.ai ...
    Suggested
    Full time
    Work at office

    Interface

    San Francisco, CA
    14 hours ago
  •  ...role Mixedbread has shipped a major new version of its product and is gaining traction with customers. We're looking for a Chief of Staff to help the founders keep the company focused, organized, and moving. This role spans execution, operations, hiring, and strategic... 

    Mixedbread

    San Francisco, CA
    4 days ago
  • $150k - $175k

     ...together. About You Most business education happens from a distance. This role puts you in the room where it's made. We're hiring a Chief of Staff who gets genuine energy from making things run well, and who wants to learn how a real company grows by doing the actual work,... 
    Temporary work
    Work at office
    Local area
    Worldwide
    Monday to Friday
    Flexible hours
    3 days per week

    BBG Ventures

    San Francisco, CA
    14 hours ago
  • $124.68k - $187.02k

     ...Job Description Summary Position Summary The Chief of Staff serves as a trusted strategic advisor and operational partner to the Chief Executive Officer, helping maximize executive effectiveness while accelerating execution of Mosaic Health’s highest-priority strategic... 
    Work at office

    (Mosaic Shared Services) Millennium Healthcare Management Se...

    San Francisco, CA
    2 days ago
  • $250k - $275k

     ...Private Family Office / Philanthropy We are seeking an experienced, highly organized, and discreet Executive Personal Assistant / Chief of Staff to support a philanthropic principal and oversee the day-to-day operations of a private home office. This is a high-touch role... 
    Full time
    Temporary work
    For contractors
    Work at office
    Work from home
    Home office
    Monday to Friday
    Afternoon shift

    Career Group

    San Francisco, CA
    4 days ago
  • $130k - $200k

     ..., and are excited to shape the future of real-world AI alongside a high-performance team. The Role We are looking for a Chief of Staff to the CEO located in the Bay Area, or Chicago, IL to partner closely with Presto’s leadership team and support the execution... 
    Work at office

    Presto Phoenix, Inc.

    San Francisco, CA
    2 days ago
  •  ...As Chief of Staff at Emanate, you’ll work directly with the founder to turn company priorities into execution across hiring, operations, GTM, finance, and team systems. You’ll bring structure to fast-moving work-streams, drive follow-through on critical decisions, and... 

    Emanate

    San Francisco, CA
    14 hours ago
  • $165k - $225k

     ...Chief Of StaffCareer Renew is recruiting for one of its clients a Chief of Staff - this is an onsite role in San Francisco. Salary range: 165-225K USD base plus benefits plus equity. We are building AGI for banking. We're replacing decades-old legacy systems with AI-native... 

    Career Renew

    San Francisco, CA
    14 hours ago
  •  ...restructure how all of that work gets done, and no tool is built for that transition yet. About the Role We're looking for a Chief of Staff to work shoulder to shoulder with our founder and help run the company. This is a strategic, full-stack role: you'll help set... 
    H1b
    Immediate start

    Luzidos Inc.

    San Francisco, CA
    3 days ago
  •  ...review candidate profiles across active roles and use resumes/profiles to understand which backgrounds may be a fit. THE ROLE As a Chief of Staff, you may work on projects that require strong execution, communication, analytical judgment, and the ability to move quickly in... 

    Career-Launch.net

    San Francisco, CA
    14 hours ago
  •  ...backed by Khosla Ventures and Y Combinator . We're still just getting started. The Role We are hiring our first Chief of Staff to operate out of the founder's office, working directly with our CEO and partnering closely across the exec team. This is a... 
    For contractors
    Work at office
    Local area

    Broccoli

    San Francisco, CA
    14 hours ago
  •  ...Our client, a rapidly scaling AI finance startup, is hiring a Chief of Staff as their first internal operations hire. You'll work directly with the CEO and CTO to drive the company's highest-priority initiatives — from scaling the team to owning financials to leading... 

    StaffGreat.com

    San Francisco, CA
    1 day ago
  • $100k - $250k

     ...Chief Of StaffBluejay is building the simulation, evaluation, and observability layer for voice + text AI agents. We work with Fortune...  ...months since inception.Now we're looking for a cracked Chief of Staff to be the founder's force multiplier and help run the company. We... 

    Bluejay (yc X25)

    San Francisco, CA
    3 days ago
  • $153k - $183k

     ...intersection of botany, neuroscience, AI, and climate, with our first commercial deployment on the horizon. The Role We’re hiring a Chief of Staff to make the business side of the company run while our CEO does the thinking work only he can do. Our technical org, research,... 
    Permanent employment
    Full time
    Work at office
    Local area
    Immediate start

    The Electric Plant

    San Francisco, CA
    2 days ago
  • $180k - $300k

     ...value chain. This is a unique opportunity to be at the forefront of shaping a new paradigm in AI and insurance. The role As Chief of Staff, you’d sit at the center of the business and work directly with Rushil on the most strategic initiatives across the company.... 
    Full time
    Work experience placement
    Work at office
    Local area

    Nirvana Insurance

    San Francisco, CA
    1 day ago
  • $180k - $240k

    You will work directly with the founders as a force multiplier: owning the things that fall between functions, running the operating cadence, and turning ambiguity into a plan. This is a high-trust, high-ownership role for an operator who wants to see the whole company...

    ATBF Labs

    San Francisco, CA
    4 days ago
  • $175k - $300k

    About Us FlowGen Labs is a frontier enterprise AI company building the zero-touch enterprise: context-aware agents that operate inside highly customized SAP environments at machine speed, grounded in each company’s ontology, live operational data, and operating procedures...
    Full time
    Visa sponsorship

    FlowGen Labs, Inc.

    San Francisco, CA
    1 day ago
  • $140k - $210k

     ...Chief of StaffTitle of Role: Chief of StaffLocation: San Francisco, onsiteCompany Stage of Funding: Seed — Software Development, Government, Defense, AI, Enterprise, B2BOffice Type: OnsiteSalary: $140K–$210KCompany DescriptionWe're representing a dynamic company that is... 

    Recruiting from Scratch

    San Francisco, CA
    14 hours ago
  • $170k - $200k

     ..., Weave is designing and building the AI workbench for the entire therapeutic lifecycle. About the Role Weave is looking for a Chief of Staff to the CEO. This role has two primary remits: The first is ownership of Weave’s "operating system". Building and running the necessary... 
    Work at office
    Remote work

    Weave, Inc.

    San Francisco, CA
    14 hours ago
  •  ...and email Flam Codes: Integrate with physical channels (outdoor ads, CTV, retail stores, events) Job Overview Flam is hiring a Chief of Staff to act as the operational quarterback for the CEO and broader leadership team. You’ll work directly with the CEO and closely support... 
    Shift work

    ESP Engineered

    San Francisco, CA
    14 hours ago
  • Mission TAR’s mission is to power intelligence for the world. We are building the world’s first off-grid power plant for data centers powered by renewable technologies. Mission TAR’s mission is to power intelligence for the world. We are building the world’s first...
    For contractors
    Relocation package

    Tar Inc

    San Francisco, CA
    4 days ago
  •  ...a Series B on the horizon and a growing portfolio of partnerships with drug developers and patient advocacy groups, we need a Chief of Staff who can operate as a true right hand to the Founder and CEO — someone who runs toward complexity, brings structure to ambiguity... 
    Work at office
    Flexible hours
    Shift work

    Asymmetric Capital Partners

    San Francisco, CA
    4 days ago
  •  ...expanding our partnerships with top autonomy companies and accelerating our research into video‑reasoning models. We’re seeking a Chief of Staff to work directly with the founders on the company’s most critical strategic, operational, and communication initiatives. This... 

    Nomadic AI

    San Francisco, CA
    4 days ago
  • $212k - $276k

     ...empowers our clients to accelerate transit, enhance street safety, and drive toward a sustainable future. Job Summary The Chief of Staff partners closely with the CEO and executive leadership team to help drive and shape corporate strategy, then operationalize it... 

    Hayden AI

    San Francisco, CA
    4 days ago
  •  ...and we need someone to help our CEO and leadership team move faster, with less breakage. About the Role We're hiring our first Chief of Staff to unlock our next phase of growth. Too much context lives in founder's heads. Roles and responsibilities are unclear, key projects... 
    Shift work

    Featherless.ai

    San Francisco, CA
    4 days ago
  •  ...the team 3x's in size Build and run RevOps across our commercial and federal businesses What we’re looking for 1-5 years of past Chief of Staff/Operating experience Scrappy entrepreneur mindset, bias to action Willingness to move to SF and open to travel Thrives in... 
    For contractors

    Usul

    San Francisco, CA
    4 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Chief of Staff. Be the first to apply!