Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Preclinical R&D Expert - In-house Drug Development

Part-time

Mercor

Mercor is partnering with a venture-backed AI lab building frontier AI platforms and physics-based foundation models for chemistry, materials science, and drug discovery. They're extending their platform into new areas of pharmaceutical development and are looking for hands-on preclinical R&D experts across drug modalities to help guide what they build.

Are you a preclinical R&D scientist who has taken drug programs from the bench toward the clinic — and curious how AI is reshaping drug discovery? This is a hands-on role that blends your wet-lab and translational experience with a growing understanding of how scientific data trains the next generation of AI models.

In this role, you'll:

Review technical materials and real-world R&D data in your area of expertise

Label, classify, and annotate scientific data and model outputs to improve model performance

Provide expert perspective on key scientific and development decisions (target/modality selection, optimization, trade-offs, risk)

Help define structure and quality standards for the client's dataset pipeline

Participate in expert discussions, interviews, and research engagements

You're a strong fit if you:

Have hands-on, non-administrative preclinical R&D experience at a company that develops its own drug assets in-house and has taken programs to the clinic — Must Have

Work in a core R&D function: discovery biology, medicinal chemistry, protein/antibody engineering, computational, in vivo/translational, pharmacology/PK-PD, toxicology, or CMC/formulation — Must Have

Have hands-on experience with one or more drug modalities (small molecules, monoclonal antibodies, peptides, ADCs, bispecifics, mRNA, siRNA, ASOs, PROTACs, molecular glues, cell therapies, gene therapies, radioligand therapies, etc.) — Must Have

Have 5+ years of relevant industry R&D experience (flexible based on depth)

Have taken a program through lead optimization or IND-enabling/preclinical development (nice to have)

Have experience at mid-sized, emerging, or resource-constrained biotech — ideally currently outside the top-20 pharmaceutical companies (nice to have)

This is a hands-on preclinical R&D role — likely not the right fit if your work is mainly CRO/CDMO services, academic-only, QC/analytical-only, clinical-development-only, diagnostics, or regulatory/medical-writing.

Your work will directly feed into the models reshaping how medicines are discovered, helping intelligent systems reason about real-world pharmaceutical R&D.

Here are more details about the role:

You will interface directly with the client team.

This is an ongoing, part-time engagement of roughly 10 hours per week.

Seniority welcome from individual contributor through Director.

We consider all qualified applicants without regard to legally protected characteristics and provide reasonable accommodations upon request.

Vacancy posted 1 day ago
Similar jobs that could be interesting for youBased on the Preclinical R&D Expert - In-house Drug Development in San Francisco, CA vacancy
  • $60 - $100 per hour

     ...and Jack Dorsey . Position: Preclinical R&D Expert – ADC & Bispecifics Type: Contract...  ...perspective on key scientific and development decisions, including target/...  ...at a company that develops its own drug assets in-house and has taken programs to the clinic... 
    House
    Contract work
    Summer work
    Remote work

    Mercor

    San Francisco, CA
    a month ago
  • $60 - $100 per hour

     ..., General Catalyst , Peter Thiel , Adam D'Angelo , Larry Summers , and Jack Dorsey . Position: Preclinical R&D Expert – In-house Drug Development Type: Contract Compensation: $60–$100/hour Location: Remote Commitment: 10 hours/week... 
    House
    Contract work
    Summer work
    Remote work

    Mercor

    San Francisco, CA
    23 days ago
  •  ...where your expertise fuels the development of the most advanced AI...  ...hiring a senior pharmaceutical R&D domain expert to work directly with a...  ...development work. Your drug development expertise is the...  ...chemistry and lead optimization, preclinical pharmacology and toxicology... 
    Suggested
    Full time
    Contract work
    Part time
    Freelance
    Live in
    Relocation
    Relocation package

    Mercor

    San Francisco, CA
    13 days ago
  • $175 per hour

     ...week pilot Commitment: 10–20 hours Role Responsibilities Create and critique rubrics that analyze commercial drugs and drug-development programs. Size the patient population for a given drug or indication, including prevalence and incidence. Judge the... 
    Suggested
    Hourly pay
    Contract work
    For contractors
    Summer work
    Remote work

    Mercor

    San Francisco, CA
    5 days ago
  • $100 per hour

     ...Larry Summers , and Jack Dorsey . Position: Corporate Development Expert Type: Contract Compensation: $85–$100/hour Location...  ...files. Qualifications Must-Have ~4+ years in an in-house corporate development or M&A role at an operating company.... 
    House
    Remote job
    Contract work
    Summer work

    Mercor

    San Francisco, CA
    5 days ago
  • $181.8k - $337.6k

     ...Global Legal Pharma’s R&D Legal team, this Corporate...  ...as Research and Early Development, Clinical Operations,...  ...this pipeline includes drug, device, digital and integrated...  ...and subject matter experts to support the above...  ...California’s Registered In-House Counsel program.... 
    House
    Full time
    Local area
    Immediate start
    Remote work
    Relocation package

    Genentech

    South San Francisco, CA
    4 days ago
  • $300 per month

     ...with frontier AI labs to accelerate model development through high-quality training data,...  ...are seeking Computational Life Sciences experts with strong scientific programming skills...  ...neuroscience, biostatistics, computational drug discovery, computational biochemistry,... 
    Contract work
    Part time
    For contractors

    Turing

    San Francisco, CA
    1 day ago
  •  ...with frontier AI labs to accelerate model development through high-quality training data,...  ...are seeking Computational Life Sciences experts with strong scientific programming skills...  ...neuroscience, biostatistics, computational drug discovery, computational biochemistry,... 
    Contract work
    Part time
    For contractors

    Turing

    San Francisco, CA
    1 day ago
  • $150 per hour

     ...week pilot Commitment: 10–20 hours Role Responsibilities Create and critique rubrics that analyze commercial drugs and drug-development programs. Interpret clinical trial endpoints and judge whether results would change prescribing. Assess implications... 
    Hourly pay
    Contract work
    For contractors
    Summer work
    Remote work

    Mercor

    San Francisco, CA
    23 days ago
  • $224.3k

    General Information Job Title Expert Manager, Product Management & Innovation Job ID 107751 Work Areas Product Management...  ...teams alongside our general consultants and clients to lead development of omnichannel solutions across a wide range of industries and... 
    Permanent employment
    Full time
    Work at office
    Local area
    Home office
    3 days per week

    Bain & Company

    San Francisco, CA
    7 days ago
  • $85 per hour

     ...contractor role, you will work as a Brand & Strategy Subject Matter Expert (SME) to review AI-generated brand strategy, positioning, and go...  ...consulting, or integrated marketing strategy (agency or in-house). ~ Strong command of positioning and messaging (value prop, proof... 
    House
    Hourly pay
    Temporary work
    For contractors
    Immediate start
    Remote work

    SuperAnnotate

    San Francisco, CA
    1 day ago
  • $70 per hour

     ...contractor role, you will work as an Advertising Subject Matter Expert (SME) to review AI-generated advertising outputs and/or create expert...  ...in advertising and/or performance marketing (agency or in-house), with hands-on campaign ownership. ~ Strong command of ad fundamentals... 
    House
    Hourly pay
    Temporary work
    For contractors
    Immediate start
    Remote work

    SuperAnnotate

    San Francisco, CA
    1 day ago
  • $55 per hour

     ...contractor role, you will work as a Social Media Subject Matter Expert (SME) to review AI-generated social content and social strategy...  ...of professional experience managing social media for brands (in-house or agency), including content creation and performance reporting... 
    House
    Hourly pay
    Temporary work
    For contractors
    Immediate start
    Remote work

    SuperAnnotate

    San Francisco, CA
    1 day ago
  •  ...to test model judgment on real trade work. AfterQuery builds the expert evaluation data that frontier AI labs use to measure and improve...  ...site safety. Flag advice that reads plausible but would burn a house down or fail inspection, the misses only a working electrician would... 
    House
    Weekly pay
    Contract work
    Temporary work
    For contractors
    Apprenticeship
    Remote work
    10 hours per week

    AfterQuery

    San Francisco, CA
    1 day ago
  • $300 per month

     ...companies, working with frontier AI labs to accelerate model development through high-quality training data, evaluations, and engineering...  ...approved task About the Role We are seeking Mathematics experts to develop realistic, terminal-based scientific tasks for... 
    Contract work
    Part time
    For contractors

    Turing

    San Francisco, CA
    1 day ago
  •  ...Location: Remote Job Overview We are seeking experienced in-house General Counsels for a part-time opportunity supporting an...  ...related AI outputs, perform simulated negotiations, and provide expert legal feedback to improve AI systems' ability to identify risks... 
    House
    Remote job
    Contract work
    Part time
    For contractors

    YO AI Labs

    San Francisco, CA
    2 days ago
  •  ...frontier AI labs use to test model judgment. AfterQuery builds the expert evaluation data that frontier AI labs use to measure and improve...  ...at least two years of corporate or M&A practice at a firm or in house. Deal lawyers who have owned real workstreams, drafting,... 
    House
    Weekly pay
    Contract work
    Temporary work
    For contractors
    Remote work
    10 hours per week

    AfterQuery

    San Francisco, CA
    1 day ago
  •  ...frontier AI labs use to test model judgment. AfterQuery builds the expert evaluation data that frontier AI labs use to measure and improve...  ...years of litigation practice at a firm, in government, or in house. Litigators who have owned real motion practice, discovery, and... 
    House
    Weekly pay
    Contract work
    Temporary work
    For contractors
    Remote work
    10 hours per week

    AfterQuery

    San Francisco, CA
    1 day ago
  • $23 - $25 per hour

     ...together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our...  ...met. Provide food, water and clean housing to animals according to applicable...  ...from target identification through preclinical development. Charles River also provides... 
    House
    Hourly pay
    Contract work
    Local area
    Worldwide
    Flexible hours

    Charles River

    San Francisco, CA
    4 days ago
  •  ...product judgment scenarios frontier AI labs use to test model reasoning on prioritization, specs, and strategy. AfterQuery builds the expert evaluation data that frontier AI labs use to measure and improve their models. We're hiring product managers as contractors to... 
    Weekly pay
    Contract work
    Temporary work
    For contractors
    Remote work
    10 hours per week

    AfterQuery

    San Francisco, CA
    1 day ago
  •  ...experienced Corporate Counsels with strong in-house experience in technology transactions....  ..., negotiation, redlining, and playbook development to review and evaluate AI-generated...  ...generated contract analysis and provide expert feedback. Develop playbooks,... 
    House
    Remote job
    Full time
    Contract work
    Part time
    For contractors

    YO AI Labs

    San Francisco, CA
    2 days ago
  •  ...look dated. Our view is that drug and therapy discovery will become...  ...our scientific work is the development of physics-based mathematical...  ...that modeling, we run an in-house wet lab that generates the...  ...to work closely with domain experts outside your own field We... 
    House
    Immediate start

    Tabula Inc

    San Francisco, CA
    3 days ago
  •  ...image generation work frontier AI labs run. AfterQuery builds the expert evaluation data that frontier AI labs use to measure and improve...  ...realistic brand and layout briefs, the kind an agency or in house team would actually assign. Write reference critiques with the typography... 
    House
    Weekly pay
    Contract work
    Temporary work
    For contractors
    Remote work
    10 hours per week

    AfterQuery

    San Francisco, CA
    1 day ago
  • $150 per hour

     ...Dorsey . Position: Public Interest Attorney (Civil Justice Expert) Type: Contract Compensation: $150/hour Location:...  ...for accuracy and practical usefulness. Evaluate scenarios in housing , family law , consumer protection , debt collection ,... 
    House
    Contract work
    Summer work
    Remote work

    Mercor

    San Francisco, CA
    23 days ago
  •  ...Senior Scientist I for a 12+ month temporary contract to lead drug product and device development efforts. The role combines technical laboratory work with...  ...parenteral dosage forms Design and execute in-house laboratory studies including stability assessments and analytical... 
    House
    Contract work
    Temporary work

    Vir Biotechnology

    San Francisco, CA
    10 days ago
  •  ...consulting work and provide actionable feedback. Preferred Qualifications MBA or Master's degree preferred. Experience developing evaluation rubrics or reviewing consulting deliverables. Strong proficiency in executive communication and presentation development.... 
    Remote job
    For contractors

    YO AI Labs

    San Francisco, CA
    2 days ago
  • $160.8k - $209.1k

     ...ambition is to become a high-performing house of iconic American brands that shape culture...  ...to the Vice President, Materials R&D, you will lead an R&D Materials team responsible...  ...to Design, ensuring fabric and material development begins with and supports the creative vision... 
    House
    Minimum wage
    Seasonal work

    Gap

    San Francisco, CA
    7 days ago
  • $85k - $100k

     ...where we encourage the use of professional development that staff can utilize throughout their...  ...settings, helping clients access housing, primary care, benefits, employment, substance...  ...symptoms, treatment alternatives, drug properties and interactions, and preventative... 
    House
    Full time
    Local area

    Family Service Agency San Francisco

    San Francisco, CA
    5 days ago
  •  ...strategic partners and trusted advisors embedded directly alongside R&D and product leaders.As AI reshapes software and the way teams...  ...practice law in your jurisdiction.Background in a law firm and in-house legal team.Strong generalist product counseling skillset, with the... 
    House
    Work at office
    Local area
    Flexible hours

    Atlassian

    San Francisco, CA
    4 days ago
  • $46.92k

     ...environment that fosters students' academic, emotional, and social development so they can reach their full potential. Responsibilities...  ...$180,000 total compensation per couple, including free housing, meals while on duty, utilities, and more) Comprehensive benefits... 
    House
    Full time
    Relocation
    Relocation package
    Flexible hours
    Weekday work

    Milton Hershey School

    Daly City, CA
    14 hours ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Preclinical R&D Expert - In-house Drug Development. Be the first to apply!