Machine Learning Engineer/Senior Machine Learning Engineer - Devops, AI for Drug Discovery (South San Francisco)
$147.6k - $274kGenentech
The PositionA healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.The OpportunityAt Roche's AI for Drug Discovery (AIDD) group (Prescient Design), we are revolutionizing drug discovery with cutting-edge machine learning techniques. We are seeking a highly motivated and skilled ML Infrastructure DevOps Engineer to join our growing team within Genentech Research and Early Development AI Drug Development (gRED AIDD). This role is crucial for building and maintaining the scalable and robust infrastructure that powers our machine learning initiatives. The ideal candidate will be proactive, user-facing, and possess a get-it-done attitude, while consistently adhering to corporate standards and best practices.What you'll doMachine Learning Engineer - DevOpsDesign, implement, and maintain scalable and reliable ML infrastructure on AWS.Automate deployment, monitoring, alerting, and operational tasks using tools like Terraform and Helm.Manage and optimize CI/CD pipelines and Git repositories for ML projects, ensuring efficient version control to support collaboration and deployment.Collaborate closely with ML engineers and data scientists to understand their infrastructure needs and provide solutions.Troubleshoot and resolve infrastructure-related issues in a timely manner.Implement and enforce security best practices for ML infrastructure.Document infrastructure designs, processes, and operational procedures.Contribute to initiatives independently as part of a team, delivering assigned outputs.Proactively identify issues and gaps, proposing ideas and suggestions for improvements.Senior Machine Learning Engineer - DevOpsLead the architecture and delivery of significant technical solutionsMentor junior engineers and drive technical alignment and influence across teamsDesign, implement, and maintain scalable and reliable ML infrastructure on AWS.Demonstrated ability to lead technical projects from conception to completion and deliver high-quality, scalable, and reliable software. to Who you areAutomate deployment, monitoring, alerting, and operational tasks using tools like Terraform and Helm.Manage and optimize CI/CD pipelines and Git repositories for ML projects, ensuring efficient version control to support collaboration and deployment.Collaborate closely with ML engineers and data scientists to understand their infrastructure needs and provide solutions.Troubleshoot and resolve infrastructure-related issues in a timely manner.Implement and enforce security best practices for ML infrastructure.Document infrastructure designs, processes, and operational procedures.Contribute to initiatives independently as part of a team, delivering assigned outputs.Proactively identify issues and gaps, proposing ideas and suggestions for improvements.Who you areMachine Learning Engineer - DevOpsBS/MS with 2-3 years of industry experience requiredProven experience in designing, deploying, and managing infrastructure on Amazon Web Services (AWS), including services such as EC2, S3, RDS, EKS, SageMaker, etc.Strong proficiency with Git and Git repository management.Hands-on experience with Terraform for infrastructure provisioning and management.Experience with Helm for deploying and managing applications on Kubernetes.Proficiency in scripting languages (e.g., Python, Bash) for automation.Excellent problem-solving skills and a strong ability to debug complex issues.Strong communication and interpersonal skills to effectively collaborate with cross-functional teams and user-facing interactions.Demonstrated ability to take initiative, anticipate needs, and drive projects to completion.Ability to thrive in a fast-paced environment and adapt to evolving requirements while adhering to corporate guidelines.Ability to write clean code with little syntax/convention feedback.Applies software engineering best practices (linting automation, unit testing, documentation, CI/CD).Familiarity with modern machine learning methods.Knowledge of and experience with high-performance computing, distributed systems, and cloud computing.Senior Machine Learning Engineer - DevOpsBS/MS with 3-5 years of industry experience requiredProven experience in designing, deploying, and managing infrastructure on Amazon Web Services (AWS), including services such as EC2, S3, RDS, EKS, SageMaker, etc.Strong proficiency with Git and Git repository management.Hands-on experience with Terraform for infrastructure provisioning and management.Experience with Helm for deploying and managing applications on Kubernetes.Proficiency in scripting languages (e.g., Python, Bash) for automation.Excellent problem-solving skills and a strong ability to debug complex issues.Strong communication and interpersonal skills to effectively collaborate with cross-functional teams and user-facing interactions.Demonstrated ability to take initiative, anticipate needs, and drive projects to completion.Ability to thrive in a fast-paced environment and adapt to evolving requirements while adhering to corporate guidelines.Ability to write clean code with little syntax/convention feedback.Applies software engineering best practices (linting automation, unit testing, documentation, CI/CD).Familiarity with modern machine learning methods.Knowledge of and experience with high-performance computing, distributed systems, and cloud computing.Preferred Experience with MLOps platforms and tools.Familiarity with CI/CD pipelines for ML workflows.Knowledge of monitoring and logging tools (e.g., Prometheus, Grafana, ELK stack)Relocation benefits are NOT available for this job postingThe expected salary range for this position based on the primary location of California for the Machine Learning Engineer is $147,600, - $274,000 and New York is $141,100 - $262,100, and the Senior Machine Learning Engineer for California is $167,400 - $310,800 and New York is $160,100 - $297,300. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.Benefits#ComputationCoE#tech4lifeComputationalScience #tech4lifeAIGenentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.Job SummaryJob number: 202509-122841Date posted : 2026-05-20Profession: Data Science & AI / MLEmployment type: Full time
- ...Machine Learning Engineer (Operations) Location: South San Francisco CA (Hybrid, 3 days/week) (Not remote) Duration: Long term... ...foundation models in generative AI applications. Knowledge of... ...Learning - Specialty, AWS Certified DevOps Engineer) is a plus....DevopsFull time3 days per week
$202.8k - $376.6k
...Roche.Advances in AI, data, and... ...are transforming drug discovery and development.... ...develop AI models that learn from biological data... ...track record in machine learning,... ...for biology.As a Senior Principal Scientist... ...primary location of South San Francisco, CA is $202,800 -...SeniorFull timePart timeLocal areaWorldwideRelocation package$147.8k - $274.4k
...Roche.Advances in AI, data, and... ...are transforming drug discovery and development.... ...step-change in machine learning for drug discovery... ...scientists with strong engineering abilities who... ..., you will:As a Senior Scientist:... ...primary location of San Francisco, is $147,800 - 2...SeniorFull timePart timeWork experience placementLocal areaWorldwideRelocation package$167.4k - $310.8k
...Roche.Advances in AI, data, and... ...are transforming drug discovery and development.... ...with cutting-edge machine learning (ML) techniques.... ...We are seeking a Senior or Principal Machine... ...intersection of engineering and research,... ...location of San Francisco, is $167,400 - 3...SeniorFull timePart timeLocal areaWorldwideRelocation package$220k - $290k
...labs, its commitment to curiosity-driven discovery science and, with academic and industry partners, its vibrant drug-development pipeline, together create... ...breakthroughs.Position Description:Calico seeks Machine Learning Research Engineers to join our rapidly growing ML team....SeniorPart time$142.5k - $264.7k
...us Roche.Advances in AI, data and... ...sciences are transforming drug discovery and development. Roche... ...full-stack software engineer to join our team building... ...advanced analytics, machine learning, and other data-... ...Onsite presence, on our South San Francisco campus, is expected...SeniorFull timePart timeLocal areaWorldwideRelocation package3 days per week$156.2k - $290.2k
...candidates for both South San Francisco, CA and Mississauga,... ...The OpportunityAs a Senior Data Scientist and Statistician... ...with scientists, engineers, business leaders,... ..., and accelerate drug development.Beyond... ...methods, machine learning, and AI to interrogate complex...SeniorFull timePart timeLocal areaRelocation package$177.31k - $329.29k
...leveraging data, analytics, and AI/ML to enable fast, targeted... ....The OpportunityThe Senior Data Scientist, GenAI Foundation... ...Observability & Performance Engineering: Comprehensive mastery of observability... ....This position is based in South San Francisco, CA and offers a hybrid...SeniorFull timePart timeLocal areaRelocation package3 days per week$177.31k - $329.29k
...decisions by leveraging data, analytics, and AI/ML to enable fast, targeted actions in... ...assistant. We are looking for a strong engineer who is redefining what front-end means... ....LocationThis position is based in South San Francisco, CA and offers a hybrid schedule working...SeniorFull timePart timeLocal areaRelocation package3 days per week$120.7k - $224.1k
...seeking a highly motivated Senior Scientist / Principal... ...organoids, for drug development. Responsibilities... ...of ocular drug discovery and development.The... ...bioengineering, biomedical engineering, pharmacology, or a... ...primary location of South San Francisco, California is $120,7...SeniorFull timePart timeLocal area$147.8k - $274.4k
...Roche.Advances in AI, data, and... ...transforming drug discovery and development... ...highly motivated Senior ML Scientist... ...learning, LLMs, and/or... ...scientists, ML engineers, and computational... ...background in machine learning and a... ...primary location of San Francisco is $147,800 -...SeniorFull timePart timeLocal areaWorldwideRelocation package$198.2k - $368.2k
..., analytics, and AI to enable fast, targeted... ...value to senior stakeholders, influencing... ...technologies, machine learning, and AI to create... ...science, engineering, healthcare information... ...in standard DevOps agile setting or... ...can be based in South San Francisco or Basel and relocation...DevopsFull timePart timeWork at officeLocal areaRelocation package$147.8k - $274.4k
.... That’s what makes us Roche.Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early... ...a highly motivated and collaborative Senior/Principal Machine Learning Scientist to join the Perturbation Biology...SeniorFull timePart timeLocal areaWorldwide$244k - $320k
...Attentive is the AI marketing platform for 1:1... ...powered personalization engine delivers bespoke... ...hubs in New York City, San Francisco, London, and Sydney, Attentive... ...!About the RoleOur Machine Learning Engineering team... ...thousands of brands. As a Senior Machine Learning Engineer...SeniorFull timePart time$290k - $359.6k
...develop and test robotic and machine learning applications for an AV... ...neural networks and Generative AI to enhance object detection... ...in Data Science, Aerospace Engineering, Automotive Engineering, Computer... ...applying.SummaryLocation: San Francisco, California, United States of...SeniorFull timeTemporary workPart timeLocal areaRemote workWork from home$207.48k - $385.32k
...data, analytics, and AI/ML to enable fast, targeted... ...recommendation engines alongside advanced predictive... ...statistics, deep learning, and forecasting—and the... ...with open-source machine learning and agentic libraries... ...position is based in South San Francisco, CA at our Genentech...Full timePart timeLocal areaImmediate start3 days per week$170k - $240k
...commitment to curiosity-driven discovery science, and, with academic... ...partners, its vibrant drug-development pipeline, together... ...Description:Calico is seeking a machine learning research scientist to... ..., and/or JAXStrong software engineering skills and substantial expertise...SeniorPart time$242.8k - $357k
...the TeamThe Consumer Engineering Team is responsible... ...homepage, search, store discovery, item exploration,... ....About the RoleAs a Senior Staff Machine Learning Engineer on Core Cx,... ...system leveraging AI. You will demonstrate... ....Pursuant to the San Francisco Fair Chance Ordinance...SeniorHourly payWork at officeLocal areaRemote workFlexible hours$242.8k - $357k
...across search and discovery experiences. As a Senior Staff Engineer, you will lead the... ...technical direction for AI-first experiences,... ...modeling, deep learning, and large... ...state-of-the-art machine learning and LLM techniques... ....Pursuant to the San Francisco Fair Chance...SeniorHourly payWork at officeLocal areaRemote workFlexible hours$259k - $312k
...is revolutionizing drug discovery. insitro is harnessing... ...diseases. Our AI/ML-enabled platforms... ...vision we are seeking a Senior Director / Vice President... ...utilize insitro's machine learning expertise to achieve... ...per week) in our South San Francisco office or hybrid (~1...SeniorPart timeWork at officeHome officeFlexible hours3 days per week$183k - $238k
...efforts to accelerate drug development.... ...causal structure learning, single cell omics... ..., and other machine learning scientists... ...bioengineers, software engineers, and machine... ...you to be in our South San Francisco headquarters at leastthree... ...is a drug discovery and development...SeniorPart timeHome officeFlexible hours$215k - $235k
...efforts to accelerate drug development. At insitro, we use machine learning to derive clinically relevant... ...scientists, software engineers, computational... ...requires you to be in our South San Francisco headquarters at least... ...is a drug discovery and development company...SeniorPart timeHome officeFlexible hours3 days per week$264k - $298k
...revolutionizing drug discovery. insitro is harnessing... ...diseases. Our AI/ML-enabled... ...we are seeking a Senior Director of Project... ...development, software engineering, and data science/machine learning. As the leader of... ...onsite to our South San Francisco headquarters with...SeniorPart timeWork at officeHome officeFlexible hours3 days per week$144.9k - $269.1k
...induced proximity small molecule discovery. The ideal candidate will... ...and optimization. AI/ML for Drug Discovery: In collaboration... ...folding, generative and active learning models.Provide strategic direction... ...on the primary location of South San Francisco, CA is $144,900 - 269,100....Full timePart timeLocal areaRelocation package$185.2k - $343.9k
...exciting opportunity for an experienced AI Software Engineering manager/leader to lead the... ...performing team of software, data, and machine learning engineers, cultivating an enduring... ...objectives.Onsite presence on our South San Francisco campus is expected for at least 3...Full timePart timeLocal areaRelocation package3 days per week$141.5k - $262.9k
...plays an active role in the process of drug development from the discovery phase through marketed products. We... ...California is $141,500 - $262,900. Senior Principal ScientistPhD and post-... ...position is based in San Francisco. This role is primarily onsite.Relocation...SeniorFull timePart timeLocal areaRelocation package$164k
...About the RoleThe Data engineering team has been created... ...serve data insights using AI.Own the ETL workflows... ..., Data Science and DevOps teams Understanding of... ...local laws, including the San Francisco Fair Chance Ordinance,... ...****@*****.*** learn more about how Chime...SeniorDevopsFull timePart timeWork at officeLocal areaRemote workNight shift- ...*ALL* OF OUR JOB OPENINGS!Senior Full Stack Engineer (Backend)As a Senior Full-Stack... ...algorithms and composite AI solutions. This role offers... ...(AWS, GCP, Azure) and DevOps tools (Docker, Kubernetes,... ...Onsite collaboration in their San Francisco office.Opportunity to grow...SeniorDevopsPart timeCasual workWork at office
$143.29k - $266.11k
...cell therapy manufacturingThis position may be based out of South San Francisco or San Diego, CA.Who You AreThe successful candidate will... ...extensive experience: PhD in biological sciences, chemical engineering, or related discipline with 5+ years of relevant research and...SeniorFull timePart timeLocal areaRelocation package$220k - $235k
...Ironclad is the leading AI contracting... ...high-output Staff/Senior Staff SRE to define... ...platform and champion engineering excellence across... ...:8+ years of DevOps / SRE experience5+... ...to dive deep and learn a new product.Experience... ...based at our San Francisco headquarters. The...SeniorDevopsFull timeContract workPart timeWork at office
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