Postdoctoral Research Associate - Developmental Neurobiology - Proteostasis and muscle-brain signali

We are seeking a highly motivated postdoctoral fellow to join the group of Dr. Fabio Demontis (

The lab ( ) is located in the Department of Developmental Neurobiology at St. Jude Children's Research Hospital in Memphis, TN, USA. We use mice and Drosophila to decipher the conserved mechanisms of muscle aging and proteostasis, and how muscle-derived signals (myokines) affect proteostasis and the progression of age-related diseases in the central nervous system (Genes&Development, 2020; Cell Metabolism, 2021; Trend in Molecular Medicine, 2026; Developmental Cell, 2026).

Requirements: This position is restricted to applicants that did not start already postdoctoral training elsewhere. In addition to a Ph.D (recently awarded or upcoming), the candidate should have expertise in molecular, biochemical, and cell biological techniques. Training in Drosophila neurobiology and tauopathy is preferred but not required. Candidate should have the ability to work independently as well as in collaborative research efforts, and have a strong desire to make a major contribution to the field of aging and neurobiology. The fellow will benefit from both the outstanding research facilities and the highly collaborative St. Jude community.

Interested applicants should send their CV, a cover letter describing research experience and interests, and names and addresses of three references to: View email address on nature.com

St. Jude Children's Research Hospital is a world-class research institution. Our 300 faculty work across the spectrum of basic, translational, clinical, and population science in a highly collaborative multidisciplinary environment that includes a Nobel laureate and members of the National Academy of Science and the National Academy of Medicine. St. Jude is ranked on Fortune Magazine's "Best Workplaces in Health Care & Biopharma" and Glassdoor's "Best Places to Work," and is located in the heart of Memphis, Tennessee, a vibrant and friendly city at the historic American crossroads of music, trade, food and culture.

We are in pursuit of the brightest minds in biomedical sciences, individuals poised to contribute to our research progress. Other than access to top-quality scientists and mentors, as a postdoctoral trainee at St. Jude, you will have:

• A Blend of Academic Freedom and Industrial Efficiency : Access to shared resources and facilities led by expert scientists, coupled with cutting-edge technology, accelerates research productivity.

• Customized Professional and Career Growth: Experience specifically designed programs to enhance professional growth and career readiness empowering postdocs for success beyond their training. This includes access to grant writing workshops, individual development plans, teaching and mentoring opportunities, non-research career advancement programs, professional development allowance, and so much more.

• Competitive Compensation: Embark on your journey with a competitive salary, comprehensive benefits, and generous relocation assistance, reflecting our commitment to recognize and invest in talent.

St. Jude is an Equal Opportunity Employer

No Search Firms

St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

We are committed to a human-centered hiring experience. Technology may support portions of our process, but recruiting decisions involve human review and engagement. Learn more about our approach to AI .

St. Jude is an Equal Opportunity Employer

No Search Firms

St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.