Senior Principal Scientist

Senior Principal Scientist Working with Us Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Job Duties: Use technical knowledge to support the development of cellular drugs in the Chemical Manufacturing Control (CMC) program. Act as a resource for the Cell Therapy Analytical Development department in support of product release, characterization, and in-process testing of cellular drug products. Prepare actionable strategies to ensure alignment with business objectives. Implement analytical strategy to ensure successful project execution. Collaborate with various teams to build cellular process. Conduct DP analytical risk identification, assessment, and mitigation. Justify drug product specifications for clinical programs. Serve as an author for analytical sections of CMC submissions and respond to regulatory questions. Telecommuting permitted up to 2 days per week. Requirements: Employer will accept a Master's degree or foreign equivalent degree in Biochemistry, Molecular Biology, or a related field, and four (4) years of work experience as a Medical Scientist or related occupation. Must have four (4) years of experience in the following skills (which may be gained concurrently):- Developing Chemistry, Manufacturing, and Controls (CMC) analytical strategies for cell and gene therapy products and biologics products;- Utilizing gene editing technologies such as CRISPR-Cas9 to create engineered T-cells;- Analyzing large datasets to for multiple clinical cellular products;- Drafting technical regulatory filings including Investigational New Drug (IND) amendments,- Biologics License Applications (BLAs), briefing books, and regulatory responses; and- Developing and transferring cellular or biologics analytical methods that are suitable for use in QC or characterization of product. Additionally, employees are eligible for an annual discretionary bonus, and benefits including healthcare, leave benefits, and retirement benefits. BMS operates a pay-for-performance compensation philosophy and your total compensation may vary based on role, location, and firm, department and individual performance. The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include: Health Coverage: Medical, pharmacy, dental, and vision care. Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP). Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support. Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown. *Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program." Bristol-Myers Squibb