Senior Business Analyst, Commercial Operations

Job Description:The Senior Business Analyst, Commercial Operations, leads integrated commercial analytics and predictive insight generation across Xeris’ portfolio. This role connects independent data streams, identifies performance drivers, develops business triggers for next-best-action opportunities, and applies advanced analytics to support marketing mix, access, patient journey, and commercial investment decisions. The individual will serve as a cross-functional analytics partner to Commercial, Marketing, Market Access, Patient Services, Finance, IT, and external vendors, helping improve revenue predictability, promotional effectiveness, and scalable decision-making across the commercial organization.Essential Job FunctionsSynthesize and interpret commercial data across CRM, specialty pharmacy, claims, payer/access, marketing engagement, patient services, finance, and internal performance systems.Develop analytical frameworks that translate fragmented data streams into performance drivers, leading indicators, risk signals, and next-best-action triggers.Apply predictive analytics and propensity models to identify customer, patient, access, and promotional patterns that inform commercial action.Lead marketing mix and promotional effectiveness analytics by evaluating channel performance, investment response, audience engagement, and ROI indicators.Partner with Marketing and Finance to assess commercial investment tradeoffs and quantify risks, opportunities, and expected impact. Define trigger logic and business rules for commercial alerts, including patient flow disruptions, access friction, adherence risk, promotional response, and underperforming segments. Lead patient journey and access analytics by integrating payer, SP, claims, and internal data to identify leakage points and intervention opportunities. Strengthen forecast confidence by monitoring leading indicators and attributing demand variance to specific commercial, access, and market factors. Translate analytical findings into decision-ready recommendations for commercial leadership, business reviews, and cross-functional planning. Partner with Business Technology and vendors to define business requirements for data and analytics infrastructure improvements.Mentor junior analysts and contribute to team capability by establishing analytical standards and leading analytical QA processes. Skills and QualificationsBachelor’s degree in business, Analytics, Finance, Economics, Statistics, or related field. Master’s degree preferred. 5+ years of experience in pharmaceutical, biotech, medtech, or healthcare commercial operations, sales operations, business analytics, finance, or related function.Deep experience in commercial analytics within a biopharma or specialty drug context, including promotional effectiveness, field force analytics, or brand performance.Hands-on experience working with patient-level and longitudinal data, including specialty pharmacy, claims, hub, or payer datasets.Familiarity with syndicated market data platforms such as IQVIA, PantherRx, and similar data sources.Hands-on experience with SQL, Python, or R for querying and data analysisAdvanced Excel and PowerPoint skills.Experience with CRM platforms in a biopharma context, with Veeva CRM strongly preferred.Strong problem-solving skills with ability to work independently in a fast-paced environment.Proven ability to manage multiple priorities and influence stakeholders across functions.Strong written and verbal communication skills.Preferred Qualifications Experience in specialty pharma/ retail pharma/rare disease.Working knowledge of targeting/segmentation, call planning and sequencing processes.Familiarity with syndicated pharma data sources and field performance data.Experience supporting launches, new product planning, or evolving commercial models.Competencies: Customer Service focus, Teamwork & Collaboration, Attention to Detail, Self-Starter, Analytical skills, Negotiation skills, Problem Solving, Organizational skills, Project Management, Adaptability, Professionalism, Written and Verbal Communications, Presentation skills, Strategic Leadership, Functional Leadership, Strategic VisionWorking ConditionsPosition may require periodic evening and weekend work, as necessary to fulfill obligations. Periodic overnight travel.This is a hybrid role based in Xeris’ Chicago office and requires a minimum of three days per week in the office. On-site requirement may change at management’s discretion.Travel expected up to 10%, including periodic overnight travel as business needs requireThe anticipated base salary range for this position is $112,000 to $140,000.#LI-HYBRIDXeris Pharmaceuticals, Inc. (the “Company”) is an equal opportunity employer and does not discriminate based on race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. All qualified candidates are given equal opportunity and the Company’s employment selection decisions are based solely on job-related factors. NOTE: This job description is not intended to be all-inclusive. The employee may be required to perform other related duties as needed to meet the ongoing needs of the Company.The level of the position will be determined based on the selected candidate’s qualifications and experience. Final determination of the actual base salary offered depends on several factors, including but not limited to the candidate’s skills, experience, education, location, and business needs. Employees are eligible for equity or long-term incentive awards, where applicable. Field Sales role employees are eligible for a quarterly commission structure. Non-Sales role employees are eligible for an annual bonus. The Company also offers a comprehensive benefits package that includes additional elements such as paid time off benefits, various health, vision, and dental insurance options, 401(k) retirement benefits and more for eligible employees. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process. Individuals hired as temporary employees, interns, and preceptors are not eligible for commissions, bonuses, and/or long-term incentive or equity awards. Eligibility for other benefits will be based on plan documents.Accessibility & Reasonable AccommodationsIf, because of a medical condition or disability, you require a reasonable accommodation or assistance to complete any part of the application process, please send an e-mail to View email address on click.appcast.io and identify the type of accommodation or assistance you are requesting. Please include the job requisition number in your message. Please note if your request is not for this stated purpose, you will not receive a response to your email. Do not include any medical or health information in this email.Xeris participates in E-Verify. E-Verify Participation PosterEEO is the Law EEO is the LawEEO is the Law Supplement EEO is the Law SupplementPay Transparency Nondiscrimination Provision Pay Transparency Nondiscrimination ProvisionSummaryLocation: Chicago, ILType: Full time