Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Chief of Staff, CEO

$300 per month

Edison Scientific

About Us Edison Scientific builds and deploys AI scientist agents to accelerate science and the development of new medicines. We are an ambitious team run by scientists and engineers from leading institutions across biology, physics, chemistry, and AI. Role This is Chief of Staff to Sam Rodriques, Edison Scientific's co-founder and CEO. This role is one of the highest-leverage seats in the company: you will sit next to Sam, with a front-row view of how Edison is built and how we are accelerating science. That means running Sam's most critical meetings, owning the projects that fall between teams, and keeping the machine around the CEO tight and fast. You will be the person who makes sure the most important work at Edison actually moves. While at times the job may seem mundane, it means giving you access to—and oftentimes a voice in—conversations and people far beyond what your tenure anywhere else would allow. Two things matter more than anything else. First, you have to be genuinely bought into Sam and where he is taking Edison. You will carry his thinking into rooms, sometimes to people who disagree. That only works if you believe it. Second, you must have a passion and genuine curiosity for science. This is an absolute-must. We think of this as a roughly 18‑month commitment, and later a launchpad into another senior role at Edison or somewhere else. The role is in our San Francisco office in Dogpatch five days per week. Responsibilities Run the operating cadence — board prep, executive staff, planning, and KPI reviews — so decisions get made and priorities stay clear across the company. Drive CEO communications: Partner closely on everything CEO-facing. Internal: all‑hands, company emails, employee recognition. External: prep for interviews, talks, and speeches. Special projects and strategic support: Take on some of the company's most important cross‑functional work that either has no clear owner or where the current owner isn't getting the result Sam needs. Own it end‑to‑end and drive it to completion. Design and master the support engine around Sam: Make sure everything around the CEO runs smoothly, and step in to unblock when they do not. Requirements 3+ years of strategic business experience, preferably at a high‑growth tech startup, finance or consulting. High‑agency and low‑ego. You figure out what's needed and just do it. Exceptional organization and follow‑through. Nothing falls through the cracks. Strong written and verbal communication. You can write in Sam's voice and speak clearly to anyone from a scientist to a customer to an investor. Comfort in high uncertainty. You get things done without a playbook and without close oversight. AI fluency and enthusiasm — you actively use AI to create leverage in your work and are excited about where it's headed (formal AI experience not required). Willingness to commit ~18 months in this role. Experience in a demanding, fast‑moving environment (high‑growth startup, consulting, finance, operating roles, or similar). Bonus points for Bachelor’s in biology or other scientific fields. Prior founder, or early‑stage operating experience at an AI company. Experience inside a company that scaled fast. Why join us? Competitive salary and equity Full healthcare coverage; we pay 100% of premiums for you and your dependents Support for growing families, including a yearly new parent stipend and fertility coverage through Carrot Mental health support through Rula, our in‑network therapist and psychiatrist network with fast availability 12 weeks of paid parental leave for maternity, paternity, and adoption Pet care support with a yearly employer‑funded stipend for your animal companions Commuter benefits so you can pay for transit and parking with pre‑tax dollars 401(k) company matching $300 health and wellness benefit quarterly Lunch is on us every day you're in the office, and dinner is on us when you're working late Regular team offsites and company events A fast‑moving, mission‑driven culture where smart people do their best work and actually enjoy doing it Edison Scientific is an equal opportunity employer. We do not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other protected characteristic under applicable law. Compensation Range: $180K - $220K #J-18808-Ljbffr Edison Scientific

Vacancy posted 3 days ago
Similar jobs that could be interesting for youBased on the Chief of Staff, CEO in San Francisco, CA vacancy
  • $300 per month

     ...Chief Of Staff To Sam Rodriques This is Chief of Staff to Sam Rodriques, Edison Scientific's co-founder and CEO. This role is one of the highest-leverage seats in the company: you will sit next to Sam, with a front-row view of how Edison is built and how we are accelerating... 
    Suggested
    Work at office

    Edison Scientific Inc.

    San Francisco, CA
    4 days ago
  •  ...that someone else sold back. So that's what we make: a liquid market for GPU offtake. About The Role SF Compute is seeking a Chief of Staff to the CEO to serve as a strategic partner and force multiplier to the CEO. This role combines strategy, operations, and execution,... 
    Suggested
    Long term contract
    Contract work
    Fixed term contract
    Work at office
    Local area
    Visa sponsorship
    Shift work

    San Francisco Compute Co.

    San Francisco, CA
    2 days ago
  •  ...Coinbase, and Palantir, among others Build a massive, fast-growing business with billions in revenue The Role The Chief of Staff to the CEO is Garrett Lord's closest execution partner - the person who helps him get things done at extraordinary speed across... 
    Suggested
    Full time
    Freelance
    Internship
    Work at office
    Remote work
    Flexible hours

    Handshake

    San Francisco, CA
    5 days ago
  •  ...leader. This is a rare opportunity to join a company at an inflection point and help shape what it becomes. Role Overview The Chief of Staff to the CEO is a strategic operator role, not an administrative one. You will serve as the CEO’s force multiplier: owning high-stakes... 
    Suggested

    RZR Global Inc.

    San Francisco, CA
    2 days ago
  • $135k - $175k

     ...Capital, looking for builders who want to solve hard problems. The Role & Culture We are seeking a sharp, organized Chief of Staff to support HomeVision’s CEO and company operations. This role is focused on acting as a strategic operational partner to the CEO,... 
    Suggested
    Flexible hours

    HomeVision

    San Francisco, CA
    4 days ago
  •  ...The Role Pair directly with the CEO to scale the company and its impact on patients across the country. Be their force multiplier. Make them 2x more effective, every day. 5 days a week in person in San Francisco. Scope You'll span every topic the CEO touches:... 
    Work experience placement

    Healthleap AI

    San Francisco, CA
    4 days ago
  •  ...someone else sold back. So that's what we make: a liquid market for GPU offtake. About The Role SF Compute is seeking a Chief of Staff to the CEO to serve as a strategic partner and force multiplier to the CEO. This role combines strategy, operations, and execution,... 
    Long term contract
    Contract work
    Fixed term contract
    Work at office
    Local area
    Visa sponsorship
    Shift work

    SF Compute

    San Francisco, CA
    3 days ago
  •  ...note: this hiring process is being managed by Hike's current Chief of Staff who is being promoted into a new role. About Hike Medical...  ...Opportunity We're hiring a Chief of Staff to serve as the CEO's force multiplier and operational backbone of the company.... 
    Work at office
    Relocation package

    Hike Medical

    San Francisco, CA
    1 day ago
  •  ...Chief Of Staff To The CEO We believe that software is the foundation of modern civilization. Yet vulnerabilities threaten its integrity, security, and resilience. We are on a mission to secure the world's software. depthfirst is building intelligence to detect and... 
    Work at office

    DepthFirst

    San Francisco, CA
    2 days ago
  •  ...caliber team turning the art of sales into a scalable science. About the Role We're looking for a Chief of Staff who will operate as a true extension of the CEO. This is a rare opportunity to work directly alongside the CEO and gain an inside view into how a high-... 

    Nooks

    San Francisco, CA
    4 days ago
  •  ...Our client is a YC-backed AI startup transforming the $1T+ equipment industry. They are seeking a Chief of Staff to scale the CEO's impact across customer acquisition, retention, and strategic initiatives — working directly with the founder on the highest-priority areas... 
    H1b

    Coastal Wave Recruiting

    San Francisco, CA
    4 days ago
  • Allswell is transforming LGBTQ+ mental health care with a specialized clinical model and targeted payer strategies. As Chief of Staff, you will be the CEO's right hand for strategy and execution, owning high-leverage initiatives, major hires, and the narrative we present... 

    Allswell

    San Francisco, CA
    4 days ago
  • Formic, a company redefining American manufacturing, is hiring a Chief of Staff to support the CEO in driving high-impact strategies and initiatives. This role requires strong judgment, ownership, and operational efficiency. Responsibilities include maintaining CEO focus... 

    Blackhornvc

    San Francisco, CA
    3 days ago
  •  ...opportunity ahead is dramatically larger than our current team. Our CEO needs a trusted partner to help with product strategy,...  ...success, sales, and company building. That's where you come in. As Chief of Staff, you'll become the CEO's highest‑leverage partner—bringing... 
    Work experience placement

    HealthLeap AI

    San Francisco, CA
    2 days ago
  • $256k - $320k

     ...Notion, Coinbase, and Palantir, among others Build a massive, fast‑growing business with billions in revenue The Role The Chief of Staff to the CEO is one of the highest‑leverage roles at Handshake — a seat at the center of our most consequential decisions as we enter... 
    Full time
    Freelance
    Internship
    Work at office
    Remote work
    Flexible hours

    Handshake

    San Francisco, CA
    5 days ago
  • $150k - $235k

    What you will do You will work extremely closely with, and act as a force multiplier to the CEO: taking on our hardest, most complex, most interdisciplinary problems… to make sure the company runs well and WINS! You should expect the role to progress as follows: First... 
    Full time
    Work at office
    Relocation package
    Flexible hours
    Weekend work

    Cardless, Inc

    San Francisco, CA
    3 days ago
  • $135k - $175k

    A leading AI software company in San Francisco is looking for a Chief of Staff to support the CEO and streamline operations. This role involves coordinating meetings, drafting communications, and preparing fundraising materials. Candidates should have 6-10 years of relevant... 
    Flexible hours

    HomeVision

    San Francisco, CA
    5 days ago
  • Verdant Bridge Group is seeking a Chief of Staff to work directly with the Founder and CEO. This is a program management and strategic execution role, not an administrative function. You will run point on the CEO’s highest priority initiatives, keep the leadership team... 

    Verdant Bridge Group

    San Francisco, CA
    2 days ago
  • HealthLeap AI is seeking a Chief of Staff in San Francisco to partner with the CEO on product strategy, fundraising, and operational excellence. You’ll be the CEO’s trusted partner, turning ideas into scalable execution and helping HealthLeap scale from startup to industry... 

    HealthLeap AI

    San Francisco, CA
    2 days ago
  • Sapiom is seeking a Chief of Staff to the CEO in San Francisco, California. This role is at the heart of the company and entails architecting the operational backbone to ensure scalability. The candidate will translate founder intent into smooth execution, aligning key... 

    Sapiom

    San Francisco, CA
    1 day ago
  • A financial services startup in San Francisco is searching for a Chief of Staff. This part-time role involves collaborating with the CEO on various initiatives, covering marketing, compliance, and customer support. Candidates should be resourceful and able to work independently... 
    Full time
    Part time

    Finvest

    San Francisco, CA
    5 days ago
  • A cutting-edge AI company based in San Francisco is looking for a Chief of Staff. In this high-leverage role, you will partner directly with the CEO to drive strategic initiatives, build tools, and improve internal operations. We're seeking a highly proactive and visionary... 

    Arcade

    San Francisco, CA
    5 days ago
  • A pioneering AI banking startup is seeking a strategic partner to work directly with the CEO in managing critical projects during scaling. You'll coordinate cross-functional teams, drive operational excellence, and address complex challenges in a high-growth environment... 

    Casca

    San Francisco, CA
    2 days ago
  • Handshake is seeking a Chief of Staff to the CEO to translate priorities into action across our network, recruiting platform, and AI data work. You will lead the operating rhythm and own cross-functional initiatives, delivering clear outcomes with strong executive alignment... 

    Handshake

    San Francisco, CA
    5 days ago
  • Flam, based in San Francisco, is seeking a Chief of Staff to act as the operational quarterback for the CEO and leadership team. This role involves driving day-to-day execution, ensuring plans turn into action, and keeping teams aligned in a fast-paced environment. The... 

    Flam

    San Francisco, CA
    5 days ago
  • Virio, located in San Francisco, is seeking a Chief of Staff to work as an extension of the CEO, driving execution across the company. The ideal candidate will have a strong background in B2B go-to-market principles and operational rigor. This full-time, in-person role... 
    Full time
    Relocation package

    Virio

    San Francisco, CA
    5 days ago
  • $200k - $250k

    Ema is seeking a Chief of Staff to the CEO to play a pivotal role within the team. The ideal candidate will have significant experience in strategic leadership and senior positions at high-growth companies, ensuring alignment across various functions while directly supporting... 

    Ema

    San Francisco, CA
    3 days ago
  • Ethos is seeking chiefs of staff to the CEO to help train our latest language model on professional presentation and slide deck tasks. You will work remotely on a flexible schedule, supporting the CEO with high-impact board decks and executive communications. The role... 
    Remote job
    Flexible hours

    Ethos

    San Francisco, CA
    2 days ago
  • A leading AI company in San Francisco is seeking a Chief of Staff to support the CEO and CTO. This role involves strategic partnership, cross-functional initiatives, and major company decisions as they scale. Candidates should have experience in high-growth environments... 

    This is Growth

    San Francisco, CA
    5 days ago
  • Nooks in San Francisco seeks a Chief of Staff to partner directly with the CEO, driving high-impact strategic initiatives across the company. You will tackle ambiguous problems, translate goals into actionable plans, and influence cross-functional teams to execute effectively... 

    Nooks

    San Francisco, CA
    5 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Chief of Staff, CEO. Be the first to apply!