Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Applied AI Research Fellow

EVOZYNE INC

Job Description

Job Description

Evozyne is one of the few AI-native biotech companies designing de novo therapeutic proteins and advancing them toward the clinic. Our teams apply AI to develop novel therapies within complex biological systems where data is imperfect, and discoveries have meaningful impact on patients’ lives. We are transforming how the industry approaches protein engineering.

Our platform, EvoGen, is both generative and predictive. Rather than focusing on structure alone, we build models that learn how protein sequence drives function, enabling the design of novel proteins optimized across multiple objectives, including potency, stability, specificity, and immunogenicity. Our model development is tightly integrated with proprietary experimental data, enabling rapid learning from biological reality. We combine sequence-based models and variational autoencoders (VAEs) with Bayesian optimization, using experimental data to rapidly design and refine proteins into impactful therapeutics.

The Applied AI Research Fellowship at Evozyne is designed for researchers who want to stress‑test ambitious ideas against one of the most challenging frontiers in applied AI today: generative design under real‑world biological constraints. As a Fellow, you will work on foundational questions in representation learning, generative modeling, and optimization, with the opportunity to see your ideas evaluated against real experimental outcomes and translated into therapeutic programs.

Your work will directly influence how Evozyne evaluates, evolves, and deploys its generative AI models for protein design.

Who You Are

You’re excited by problems where the data is messy, the constraints are real, and the path forward isn’t obvious. You thrive in ambiguity, and you’re motivated by applying your work to real-world scientific challenges to see how your ideas hold up in practice. You are already operating at the leading edge of applied AI and want to push your thinking further by applying it to complex, high-impact challenges in drug discovery.

What You’ll Be Investigating

As an Applied AI Research Fellow, you will help drive the evolution of Evozyne’s generative AI design platform. Example research areas include:

  • Benchmarking generative protein models, including Evozyne’s own, on their ability to produce functionally diverse and biologically meaningful designs.
  • Evaluating the value of integrating large-scale metagenomic resources (e.g., Global Ocean Gene Catalog) into current internal database.
  • Exploring alternatives and extensions to Bayesian Optimization such as Knowledge Gradient, Entropy Search, and related methods for multi-objective optimization problems.
  • Developing and applying deep learning approaches for remote homology detection
  • Investigating multi-family VAE models to enable protein design when sequence support is limited or when optimizing phenotypes across protein families.

These efforts are intended to surface failure modes, challenge assumptions, and directly inform how Evozyne designs proteins and advances therapies.

Education + Experience

  • Late-stage PhD student or postdoc in a quantitative or computational field
  • Hands-on experience applying AI/ML to complex, real-world or scientific datasets
  • Experience working on problems where data is noisy, incomplete, or difficult to interpret
  • Familiarity with modern machine learning approaches (e.g., deep learning, generative models, or related methods)
  • Evidence of meaningful contribution to research, open-source work, or applied projects
  • Exposure to interdisciplinary work (e.g., biology, chemistry, physics, or other scientific domains) is a plus

Why Evozyne

Few places offer the combination of proprietary experimental data, real therapeutic programs, and the freedom to explore foundational AI questions under real biological constraints. If you want your best ideas tested where they matter most, and the chance to help redefine how AI is applied to protein design, we’d like to connect.

Vacancy posted 22 days ago
Similar jobs that could be interesting for youBased on the Applied AI Research Fellow in Chicago, IL vacancy
  • $200k - $275k

     ...A global trading firm is seeking quantitative researchers to apply state-of-the-art machine learning in solving trading problems. The ideal candidate will have a strong background in ML, statistics, and programming, with responsibilities including designing ML models... 
    Suggested
    Full time

    IMC B.V.

    Chicago, IL
    2 days ago
  • $19.23 - $26.44 per hour

     ...infection. Job Summary The Research Technical Assistant will join...  ...also collaborate closely with fellow lab members, contributing to a...  ...University of Chicago uses AI-assisted tools to streamline...  ...make hiring decisions. When applying, the document(s) MUST be uploaded... 
    Suggested
    Hourly pay
    Contract work
    Work experience placement
    Work at office
    Worldwide

    The University of Chicago

    Chicago, IL
    2 days ago
  • $19.23 - $26.44 per hour

     ...Research Analyst The Light Lab is part of the Department of Microbiology and the Duchossois...  ...) The University of Chicago uses AI-assisted tools to streamline and augment...  ...not used to make hiring decisions. When applying, the document(s) MUST be uploaded via the... 
    Suggested
    Hourly pay
    Contract work
    Work experience placement
    Work at office

    University of Chicago

    Chicago, IL
    4 days ago
  • $112.5k - $187.5k

     ...Core Responsibilities Analytics & AI Consulting Delivery - Lead complex...  ...of technical and business backgrounds. Research, Innovation & Process Improvement - Contribute...  ...and cross-functional partners, including applied AI, responsible AI, experimentation, and... 
    Suggested
    Full time
    Temporary work
    Work experience placement
    Work at office
    Flexible hours
    2 days per week

    TransUnion

    Chicago, IL
    7 hours ago
  • $90k - $120k

     ...(CTDS) at the University of Chicago is a research center whose mission is to develop the discipline...  ...team and play a critical role in AI/ML tooling, features, and improvements for...  ...as a technical subject matter expert by applying principles of data science to define and... 
    Suggested
    Full time
    Contract work
    Work experience placement
    Work at office
    Remote work

    The University of Chicago

    Chicago, IL
    4 days ago
  • $85k - $125k

     ...meaningful work-life balance.  Being a UX Researcher at iManage Means…  At iManage, we build...  ...interaction design, and support trusted AI experiences across our enterprise...  ...women and people of color are less likely to apply to jobs unless they meet all qualifications... 
    Work at office
    Local area
    Immediate start
    Flexible hours

    iManage

    Chicago, IL
    2 days ago
  • $95k

     ...Chicago invites applications for the 2027-29 cohort of CSEi Research Fellows, to be appointed at the rank of Research Fellow. We seek outstanding...  ...faculty member who has agreed to serve as mentor. If applying without a pre-matched mentor, please provide the names of faculty... 
    Relocation package

    University of Chicago - Climate Systems Engineering initiati...

    Chicago, IL
    14 days ago
  • $220k - $260k

     ...advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus'...  ...at the intersection of machine learning and clinical science, researching, designing, and deploying cutting‑edge multimodal AI models that... 
    Remote work

    Tempus AI, Inc.

    Chicago, IL
    1 day ago
  • $63.48k - $77.08k

     ...other factors. Position Highlights: Position: Post-Doc Research Fellow-Center for Psychiatric Genetics Location: Evanston, IL...  ...for publication Ability to develop scientific proposals to apply for fellowships Capable of identifying problems that may adversely... 
    Hourly pay
    Full time
    Part time
    For contractors
    Local area
    Monday to Friday
    Shift work

    Endeavor Health

    Evanston, IL
    3 days ago
  • $240k - $249.5k

     .... As a Senior Staff Data Scientist, you will go beyond individual problem solving — you will help shape the strategic direction of applied data science, mentor senior and junior scientists, and collaborate closely with engineering, product, operations, and business leaders... 
    Temporary work
    Work at office
    3 days per week

    Wonder

    Chicago, IL
    2 days ago
  • $71.31k - $102.5k

     ...stories. If you are ready to commit your efforts to a role that honors accuracy, teamwork, and compassion, we are excited to meet you. Apply today to become part of a future where science not only saves lives but also embraces the warmth of humanity in its accuracy.... 
    Full time
    Local area
    Night shift
    Weekend work

    MLee Healthcare Staffing and Recruiting, Inc

    Chicago, IL
    3 days ago
  • $184k - $299.81k

     ...sounds like a place where you can thrive, we can’t wait to meet you.WHAT YOU'LL DOBraze is seeking a Staff Applied Scientist to join our Predictive and Generative AI (PGAI) team. The team's mission is to deliver a truly engaging and personalized customer experience... 
    Work at office
    Local area
    Flexible hours

    Braze

    Chicago, IL
    1 day ago
  •  ...every test result contributes to stories of recovery and wellness. If you are eager to be part of a team that rewards accuracy, teamwork, and heart, we cannot wait to connect with you. Apply today and help champion a future where science serves humanity brilliantly.... 
    Full time
    Local area
    Weekend work
    Day shift
    Afternoon shift

    MLee Healthcare Staffing and Recruiting, Inc

    Chicago, IL
    3 days ago
  • $71.21k - $102.64k

     ...healing. If you are eager to commit to a role that rewards diligence, teamwork, and genuine care, we are excited to connect with you. Apply now and become part of a journey where scientific expertise saves lives—and where your contributions are as significant as the... 
    Full time
    Summer work
    Seasonal work
    Local area
    Day shift

    MLee Healthcare Staffing and Recruiting, Inc

    Chicago, IL
    19 hours ago
  • $71.12k - $102.27k

     ...healing. If you're ready to dedicate yourself to a position that celebrates collaboration, accuracy, and care, we are excited to meet you. Apply today and become part of a mission where science transforms lives, and where the human touch complements technical expertise.... 
    Full time
    Local area
    Shift work
    Day shift

    MLee Healthcare Staffing and Recruiting, Inc

    Chicago, IL
    19 hours ago
  • $71.21k - $102.3k

     .... If you are ready to invest your energy into a role that rewards collaboration, care, and precision, we are excited to meet you. Apply today and join us in creating a future where scientific inquiry saves lives and the human touch remains at the core of accuracy.... 
    Full time
    Local area
    Weekend work
    Day shift

    MLee Healthcare Staffing and Recruiting, Inc

    Chicago, IL
    7 hours ago
  • $71.11k - $102.19k

     ...If you are eager to dedicate your skills to a job that promotes precision, teamwork, and empathy, we can't wait to hear from you. Apply now and help shape a future where your contribution to science saves lives and where your work resonates with the human experience... 
    Full time
    Local area
    Day shift

    MLee Healthcare Staffing and Recruiting, Inc

    Chicago, IL
    19 hours ago
  • $71.21k - $102.56k

     ...lab result tells a story of hope and healing. If you're eager to contribute to a job that celebrates precision, teamwork, and compassion, we invite you to connect with us. Apply today to help shape a future where science elevates lives, melding accuracy with humanity.... 
    Full time
    Local area
    Weekend work
    Day shift

    MLee Healthcare Staffing and Recruiting, Inc

    Chicago, IL
    9 hours ago
  • $250k - $300k

     ...Chicago, United States; New York, United States IMC Trading is seeking quantitative researchers with a proven track record to apply state-of-the-art machine learning & deep learning to solve challenging trading problems. This role is part of a central ML research... 
    Permanent employment
    Full time
    Local area

    IMC Trading

    Chicago, IL
    1 day ago
  •  ...Oncology Clinical Researcher (AI Training) About the Role What if your deep expertise in cancer clinical trials could directly shape...  ...methodical - you hold AI-generated content to the same standards you'd apply in a clinical or regulatory setting Comfortable working... 
    Hourly pay
    Ongoing contract
    Contract work
    Freelance
    Remote work
    Flexible hours

    Alignerr

    Chicago, IL
    19 hours ago
  • $71.9k - $189k

     ...Clinical Research Monitor To be eligible for this position, you must reside in the same country where the job is located. Perform monitoring...  ...site monitoring experience. Good knowledge of, and skill in applying, applicable clinical research regulatory requirements. Good... 
    Full time
    Part time
    Local area
    Immediate start
    Worldwide

    MCRA, LLC

    Oak Brook, IL
    19 hours ago
  • Clinical Research Associate - Oncology - Chicago ICON plc is a world-leading healthcare intelligence and clinical research organization...  ...if you meet all of the requirements? We would encourage you to apply regardless - there’s every chance you’re exactly what we’re... 
    Local area
    Visa sponsorship
    Flexible hours

    ICON plc

    Chicago, IL
    3 days ago
  • $16 per hour

     ...ascertain adequacy and appropriateness of specimens. Data enter test requests into the Laboratory Information System (LIS) and apply appropriate barcoded labels to patient specimens or scan pre-existing barcodes. Ensure that specimens are labeled appropriately... 
    Hourly pay
    Full time
    Shift work
    Night shift

    Simple Laboratories

    Harwood Heights, IL
    4 days ago
  • $71.21k - $102.69k

     .... If you are eager to invest yourself in a role that rewards accuracy, collaboration, and compassion, we are excited to meet you! Apply today and embark on a journey where science saves livesand where compassionate care meets practical expertise. MLee Healthcare Staffing... 
    Full time
    Seasonal work
    Local area
    Day shift

    MLee Healthcare Staffing and Recruiting, Inc

    Chicago, IL
    4 days ago
  • $71.31k - $102.5k

     ...your dedication into a position that celebrates accuracy, teamwork, and compassion, we look forward to welcoming you into our team. Apply today and help pave the way for a future in which science not only saves lives but resonates with humanity. MLee Healthcare... 
    Full time
    Local area
    Weekend work
    Day shift

    MLee Healthcare Staffing and Recruiting, Inc

    Chicago, IL
    4 days ago
  • $170k - $199k

     ...team + roleWe are building an elite team, applying frontier technologies to the world’s...  ...advanced predictive insights and tactical AI into our workforce systems. Our mission is...  ...psychometrics or survey methodology to design research-backed questions.Direct experience... 
    Work at office
    Flexible hours
    Shift work
    3 days per week

    Robinhood Financial

    Chicago, IL
    4 days ago
  • $35 - $40 per hour

    Medical Laboratory Technician Location: Hines, IL Agency: 22nd Century Healthcare, Inc. Pay: $35 to $40 per hour Shift Information: Days - 5 days x 8 hours Contract Duration: 1 Years Start Date: ASAP About the Position Work with Technologists...
    Hourly pay
    Full time
    Contract work
    Immediate start
    Shift work

    22nd Century Healthcare, Inc.

    Hines, IL
    2 days ago
  • $35 - $40 per hour

    Medical Laboratory Technician Location: Hines, IL Agency: 22nd Century Healthcare, Inc. Pay: $35 to $40 per hour Shift Information: Days - 5 days x 8 hours Contract Duration: 1 Years Start Date: ASAP About the Position ~ Someone who works...
    Hourly pay
    Full time
    Contract work
    Immediate start
    Shift work

    22nd Century Healthcare, Inc.

    Hines, IL
    2 days ago
  • $32 - $37 per hour

    Medical Laboratory Technician Location: Hines, IL Agency: 22nd Century Healthcare, Inc. Pay: $32 to $37 per hour Shift Information: Days - 5 days x 8 hours Contract Duration: 1 Years Start Date: ASAP About the Position ~ Administrative...
    Hourly pay
    Full time
    Contract work
    Immediate start
    Shift work

    22nd Century Healthcare, Inc.

    Hines, IL
    2 days ago
  • $60k - $75k

     ...Research Associate The Research Associate is responsible for the execution of individual research projects, reports and memos. Candidates...  ...for employee medical, dental, and vision insurance. To apply, please submit your resume and a cover letter detailing your qualifications... 
    Internship
    Local area
    Weekend work
    Afternoon shift

    Arena

    Chicago, IL
    1 day ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Applied AI Research Fellow. Be the first to apply!