Head, Health System Strategy, Rare Diseases
$232.5k - $335.83kSanofi
Job title: Head, Health System Strategy, Rare DiseasesLocation: Cambridge, MA7 Products + 2 Launches$2.2B $3.1B (2030)2 Direct ReportsIncluding landmark AATD Therapy, 1H 2027, VENG 2H 2026About the jobJoin the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs. As Head, Health System Strategy, Rare Diseases within our US Rare Disease Leadership Team, you'll lead provider-focused strategy across a $2.2B business with 7 marketed products and 2 pipeline launches, including a landmark AATD therapy in 1H 2027. You'll build strategic partnerships with health systems and IDNs, optimize care pathways, and accelerate patient diagnosis and treatment access. This role is a member of the US Leadership Team and reports directly to the General Manager. Ready to get started?You'll be joining Sanofi's US Rare Disease business at a pivotal moment—managing a portfolio with clear growth trajectory to $3.1B by 2030, leading health system strategy for breakthrough therapies, and shaping how we partner with leading academic medical centers and integrated delivery networks to transform patient outcomes.About SanofiWe're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.Main responsibilities:Health System Strategy & Care Pathway OptimizationLead integrated health system strategy to accelerate diagnosis, optimize care pathways, and improve treatment access across the rare disease portfolioIdentify barriers across the patient journey—diagnosis, referral, treatment initiation, reimbursement—and develop targeted, scalable solutionsLeverage patient journey analytics, health economics, and real-world evidence to guide pathway strategy and institutional engagementChampion launch readiness for the landmark AATD therapy (1H 2027) across provider and health system dimensionsCollaborate with Health System leads across business units; share best practices and leverage common resourcesInstitutional Partnership & Shared Value StrategyIdentify the shared strategic priorities—the "main thing"—between Sanofi Rare Disease and senior institutional leaders, finding the intersection where patient access goals align with the institution's own clinical, operational, and outcome objectivesBuild trust-based, mutually beneficial partnerships with health system executives, department chairs, and medical directors that go beyond transactional engagement toward genuine value co-creationDesign and execute collaborative frameworks where Sanofi and institutional partners work toward a common purpose: getting the right rare disease patients diagnosed and treated fasterEngage senior stakeholders at leading academic medical centers and IDNs to uncover and activate shared opportunities that benefit patients, providers, and the health systemNavigate Legal & Compliance requirements for all health system partnerships and B2B solutions, ensuring all engagements are structured for sustainability and integrityProvider Partnerships & B2B SolutionsBuild strategic partnerships with health systems, IDNs, and provider organizations across the rare disease landscapeDesign B2B solutions that address health system needs across health information technology (HIT), operations, and patient experienceExpand key opinion leader relationships to uncover value-creation opportunities and advance rare disease awareness and diagnosisCross-Functional Leadership & CollaborationServe as the US Leadership Team subject matter expert on health system dynamics, care delivery trends, and provider engagement strategyIntegrate health system considerations into launch planning, lifecycle management, and portfolio strategyMonitor the competitive landscape and evolving care delivery models in partnership with Business Insights & SolutionsBuild, develop, and lead a high-performing team of 2 direct reportsAbout youRequired:Bachelor's degree required; advanced degree (MBA, MPH, MS, PhD) strongly preferred10+ years of experience in pharma, biotech, healthcare (medical center or large practice), or payer environment7+ years of leadership experience managing teams and cross-functional initiativesDemonstrated expertise in health system/provider strategy and partnerships with IDNs, health systems, and medical groupsProven track record in care pathway optimization and patient journey analyticsStrong business acumen with understanding of health system economics and B2B solutionsExcellent communication skills with ability to influence and negotiate at the executive levelAbility to navigate complex, highly regulated environments while managing multiple prioritiesPreferred:Experience in rare disease or specialty therapeuticsTrack record with organized customers and health system partnershipsExperience with patient journey analytics, health economics, and real-world evidenceProduct launch experience, particularly in rare disease or specialty settingsExperience with HIT integration and operational solutions for health systemsWhy choose us?Bring the miracles of science to life alongside a supportive, future-focused team. Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave. Lead health system strategy for a high-growth $2.2B rare disease business with a clear path to $3.1BPlay a pivotal role in launching a landmark AATD therapy that will transform patient livesJoin the US Leadership Team and shape strategy across the entire rare disease portfolioPartner with leading academic medical centers and health systems to co-create patient valueWork at the intersection of innovation, patient access, and institutional partnershipBe part of a mission-driven team chasing the miracles of science to improve patients' lives.Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. #GD-SG #LI-GZ #LI-HYBRID#vhdPursue progress, discover extraordinaryBetter is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!US and Puerto Rico Residents OnlySanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.North America Applicants OnlyThe salary range for this position is:$232,500.00 - $335,833.33All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.SummaryLocation: Cambridge, MAType: Full time
$206.25k - $343.75k
...Clinical Research Director - Rare DiseasesLocation:... ...Research Director (CRD), Rare Diseases Therapeutic Area, is... ...clinical development strategy for assigned projects/... ...of the immune system - and innovative pipeline... ...regulatory approvalEngage with health authorities (contribute...SuggestedFull time$225k - $310k
About This RoleThe Global Medical Director, Rare Disease (SMA) Medical Education role is part of Rare Disease (SMA/ALS) Global Medical team... ...lead for shaping and driving the global medical education strategy for Biogen's Spinal Muscular Atrophy (SMA) portfolio — spanning...SuggestedFull timeTemporary workLocal area$225k - $310k
About the RoleThe Global Medical Director, Rare Disease Evidence Generation - ALS and SMA is a... ...medical practice, support lifecycle strategy, strengthen scientific leadership, and improve... ..., Biostatistics, Epidemiology, Health Economics and Outcomes Research, Value and...SuggestedFull timeTemporary workLocal areaShift work$183k - $252k
...Education is a key member of the Global Medical Rare Disease team, reporting into the Rare Disease... ...execute the global evidence generation strategy across Biogen’s SMA and ALS portfolio,... ..., Biostatistics, Epidemiology, Health Economics and Outcomes Research, Value and...SuggestedFull timeTemporary workLocal areaWorldwide$178.5k - $257.83k
...Medical Director, Advanced Systemic Mastocytosis (aSM)... ...immune challenges, rare diseases, cancers, and neurological... ...therapies and helping Health Care Professionals and... ...and reports to the Head of US Medical Affairs,... ...Responsibilities:Medical Strategy & LeadershipDevelop U....SuggestedFull time$232.5k - $387.5k
Job Title: Medical Head, Early Pipeline, Specialty... ...immune challenges, rare diseases, cancers, and neurological... ...disease and assets strategies. About Sanofi:We’re an... ...understanding of the immune system - and innovative... ...with a wide range of health and wellbeing benefits...Full timeLocal area- ...personal experiences and belief systems—the ones that comprise us as... ...messages they are passionate about. Head of HEOR- North America (... ...focus on continuing to develop a Health Economics and Outcomes... ...Responsibilites: Be a leader in global HE strategy and capability development for...Local areaWork from homeWorldwideFlexible hours
- ...medical innovation?As the Global Medical Head, Weight Management (Obesity &... ...vision and impact to shape product and disease area strategy, build capability, drive product launches... ...healthcare professionals, patients and health systems to design and implement world-class medical...Hourly payFull timeTemporary workWork at officeLocal areaWorldwideFlexible hours3 days per week
$280.9k - $421.34k
...report to the Global Clinical Head. This is an excellent... ...therapeutic area, and functional strategies. This position offers the... ...environment within rare or cardiometabolic diseases. Willingness and ability to... ..., and leaves), as well as health, dental, and vision coverage...Full timeTemporary workWork experience placementWork at officeFlexible hours3 days per week$209.6k - $313.38k
...align to the broader overall TA strategy determined by the Sr.... ...societies within the assigned disease areas within the CNS TA. Act... ...competency with the US healthcare system and regulatory landscape is required... ..., Inc., and Otsuka Precision Health, Inc. (“Otsuka”) does not...Temporary workLocal areaFlexible hours$206.25k - $297.92k
...people with immune challenges, rare diseases, cancers, and neurological... ...understanding of the immune system - and innovative pipeline - enables... ..., and Lead Together.Develop strategy and tactics for an integrated... ...and Publications, Health Outcomes, Safety, and Clinical...Full time$206.25k - $343.75k
...with immune challenges, rare diseases, cancers, and... ...US medical/scientific strategy for Pulmonary products... ...Communications and Publications, Health Outcomes, Safety, and... ...with Field Medical Head, Medical Directors, and... ...relevant healthcare systems, the evolving medical...Full timeLocal area$130k - $209k
...collaborate in defining the Mobile Cardiac Telemetry (MCT) clinical systems product strategy for that aligns to the AM&D portfolio vision and global... ...’ locations.This is an office role.About PhilipsWe are a health technology company. We built our entire company around the...Full timeWork experience placementWork at officeLocal areaImmediate startWork visaRelocation package3 days per week$164k - $199k
...Proficiency in trial management systems, IVRS/IWRS, eTMF, EDC,... ...is a plusCurrent rare disease experience and/or gene... ...trial operational strategy and updates to... ...recently, Navreet was Head of Global Clinical Operations... ...designed to support the health, wellness, and...Contract workLocal area$197.2k - $266.8k
...position reports to the head of the Clinical Data... ...CRO outsourcing strategy and deliverables, including... ...for clinical data systems including 21 CFR Part... ...support your overall health and well-being. We offer... ...lives of people with rare and common diseases. Built on Nobel Prize...Full timeTemporary workLocal areaFlexible hours$145.9k - $234.2k
...Product Manager - Clinical Safety and Pharmacovigilance Systems to support the digital product strategy, operations, and lifecycle management of the... ...ensure patient safety and maintain compliance with global health authorities, in alignment with our values of acting with...Permanent employmentFull timeWork at officeWork from home$130k - $190k
...of therapeutic editing strategies that Beam is using to advance... ...suffering from serious diseases.Position Overview:We... ...in a scientific, health-related, or technical discipline... ...on experience with EDC systems (e.g., Medidata RAVE,... ...editing, cell therapy, rare disease, or other...Full timeInterim role$222.75k - $371.25k
...positively impact the health of 2.5 billion people by... ...understanding of the immune system with cutting-edge... ...talent to get ahead of disease together.Find out more:... ...the clinical development strategy for regulatory... ...degreeExperience in Lung or Head & Neck Oncology clinical...Full timeWork at officeLocal areaRelocation2 days per week3 days per week$206.25k - $297.92k
...people with immune challenges, rare diseases, cancers, and neurological... ...on field engagement strategies and tactics aligned to medical... ...understanding of the immune system - and innovative pipeline -... ...family, with a wide range of health and wellbeing benefits including...Full timeWork at officeRemote work$148k - $236.5k
...country/site selection, and recruitment strategy. Participate meaningfully in dose... ...materials. Oversee clinical data systems and processes: CRF design and UAT,... ...capabilities. Experience in metabolic diseases, obesity, oncology, and/or rare diseases highly desirable....For contractors- ...healthcare with SOPHiA GENETICS as our Director, Strategic Accounts - Health Systems for North America. Our missionWe believe there is a smarter,... .... Develop comprehensive account plans with clear goals and strategies to maximize revenue potential. Act as a trusted advisor,...Contract workTemporary workLocal area
$148k - $236.5k
...approaches to serious diseases with unmet medical need... ...selection, and recruitment strategy.Participate... ....Oversee clinical data systems and processes: CRF design... ...obesity, oncology and/or rare diseases highly desirable... ...courageous leaps in human health, sustainability, and beyond...For contractors- ...that deliver the development strategies for therapeutic compound(s) under... ...the specific therapeutic and disease area(s) of assignment.... ...in protocol-related KOL and Health Authority interactionsEnsures... ...-malignant hematology and/or rare diseaseProven track record of...Full timeTemporary workLocal areaFlexible hours
$252k - $378k
...scientific leadership across cross-functional teams, ensuring medical strategies are aligned with corporate objectives, patient needs, and the... .... Prior launch experience in nephrology, immunology, or rare disease strongly preferred. Experience managing and developing teams...Full timeSummer workRemote workFlexible hoursShift work2 days per week$225k - $315k
...muscular atrophy (SMA) and other rare, severe, and debilitating neuromuscular diseases. As a global leader in myostatin... ...Clinical Pharmacology, reporting to the Head of Clinical Pharmacology, will... ...clinical pharmacology strategies across multiple programs at various...Full time$237.2k - $372.79k
...therapies for patients with rare and complex diseases. Takeda believes there is... ...more to meet patients’ and health care providers’ expectations... ...Immunodeficiency leads and drives strategy for the overall global (US/... ...you will report to the Head of Primary Immunodeficiency...Minimum wageTemporary workLocal areaWorldwideFlexible hours$178.5k - $257.83k
...gastrointestinal, and rheumatologic diseases. This represents an... ...scientific stakeholder engagement strategy across the NextGen Immunology... ...understanding of the immune system - and innovative pipeline -... ...family, with a wide range of health and wellbeing benefits including...Full timeLocal areaShift work$177k - $278.08k
...unwavering commitment to deliver Better Health and a Brighter Future to people around... ...-derived therapies for patients with rare and complex diseases. Takeda believes there is tremendous... ...clinical pharmacology and pharmacometrics strategy to support PDT project progression...Minimum wageContract workTemporary workWork at officeLocal areaRemote work- ...leadership and launch excellence, leading Medical Affairs strategy, content development, KOL education programs, and support... ...accountable for advancing Rhythm’s scientific leadership in Rare Neuroendocrine Diseases including hypothalamic Obesity and other pipeline...
$196k - $285k
...genetically driven neuromuscular diseases. We are developing... ...the central nervous system (CNS) to address the... ...Affairs leads Dyne’s medical strategy and execution within... ...closely and with the Head of the Medical Science... ...PharmD) with experience in rare diseases; neuromuscular...Work at officeLocal areaNight shift
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Head, Health System Strategy, Rare Diseases. Be the first to apply!
- behavioral health registered nurse Cambridge, MA
- health policy Cambridge, MA
- health writer Cambridge, MA
- home health rn case manager Cambridge, MA
- health sciences degree Cambridge, MA
- life health Cambridge, MA
- reproductive health Cambridge, MA
- capital health Cambridge, MA
- united health group Cambridge, MA
- health information coordinator Cambridge, MA

