Senior Principal Scientist, Clinical Research - Immunology/Dermatology
$282.2kFull-time
Merck
Job Description The Senior Director (Sr. Principal Scientist) has primary responsibility for the strategic planning and directing clinical research activities involving investigational compounds in Immunology. With a focus on late-stage development, the Senior Clinical Director will manage the entire cycle of clinical development, including determination of appropriate disease indications to pursue and subsequent study design, initiation, execution, monitoring, analysis, regulatory filing, and publication. Specifically, The Senior Director May Be Responsible For:
Clinical Decision Making, Clinical Development, Clinical Documentation, Clinical Judgment, Data Analysis, Dermatology, Drug Development, Immunology Preferred Skills: Current Employees apply HERE Current Contingent Workers apply HERE US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.--As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.- For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement• We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts The salary range for this role is
$282,200.00 - $444,200.00 This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable. We offer a comprehensive package of benefits.- Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at . You can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting. San Francisco Residents Only: -We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance Los Angeles Residents Only: -We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance Search Firm Representatives Please Read Carefully-
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. -No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.- Employee Status:
Regular Relocation:
Domestic VISA Sponsorship:
No Travel Requirements:
25% Flexible Work Arrangements:
Hybrid Shift:
Not Indicated Valid Driving License:
No Hazardous Material(s):
n/a Job Posting End Date:
09/15/2026
*A job posting is effective until 11:59:59PM on the day BEFORE -the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date. Requisition ID: R416082
- Evaluating pre-clinical and translational work for the purpose of generating the early clinical development plan and Investigational New Drug applications.
- Providing clinical development support of business development assessments of external opportunities to grow the Immunology Pipeline
- Developing clinical development strategies for investigational drugs and planning clinical trials (design, operational plans, settings) based on these clinical development strategies.
- Monitoring and managing the conduct of ongoing or new clinical trials for investigational drugs.
- Analyzing and summarizing the clinical findings from studies to support decisions regarding safety and efficacy as well as new drug applications, clinical study reports, or publication; and
- Participation in internal and joint internal/external research project teams relevant to the development of new compounds
- Maintaining awareness of scientific developments within his/her area of expertise, in terms of new scientific findings, research methodologies
- Identification of scientifically and operationally strong investigators who can assist in the development of our company's investigational drugs in Immunology.
- Establishing collaborative relationships with external experts in Rheumatology, Gastroenterology, Dermatology, Pulmonary, or rare diseases, particularly those whose research focus and expertise can inform and assist the evaluation of the company's investigational drugs.
- Attending appropriate scientific meetings to maintain his or her competency and to maintain awareness of research activities in his/her area of responsibility.
- Author detailed development documents, presentations, budgets, and position papers for internal and external audiences.
- Facilitate collaborations with external researchers around the world.
- Travel on company business about twenty (20) percent of the time to manage future or ongoing clinical research projects.
- M.D., D.O., M.D./Ph.D, or D.O./PhD..
- Experience in the design and/or execution of phase 2 or 3 clinical trials specifically in Immunology
- Minimum of 3 years of clinical medicine experience
- Minimum of 5 years of industry experience in drug development
- Demonstrated record of scientific scholarship and achievement
- Strong interpersonal skills, as well as the ability to work collaboratively in a cross-functional team environment.
Clinical Decision Making, Clinical Development, Clinical Documentation, Clinical Judgment, Data Analysis, Dermatology, Drug Development, Immunology Preferred Skills: Current Employees apply HERE Current Contingent Workers apply HERE US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.--As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.- For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement• We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts The salary range for this role is
$282,200.00 - $444,200.00 This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable. We offer a comprehensive package of benefits.- Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at . You can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting. San Francisco Residents Only: -We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance Los Angeles Residents Only: -We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance Search Firm Representatives Please Read Carefully-
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. -No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.- Employee Status:
Regular Relocation:
Domestic VISA Sponsorship:
No Travel Requirements:
25% Flexible Work Arrangements:
Hybrid Shift:
Not Indicated Valid Driving License:
No Hazardous Material(s):
n/a Job Posting End Date:
09/15/2026
*A job posting is effective until 11:59:59PM on the day BEFORE -the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date. Requisition ID: R416082
Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Senior Principal Scientist, Clinical Research - Immunology/Dermatology in Boston, MA vacancy
- ...biology, DNA sequencing, immunology, and biologics drug... ...scientific and clinical data from academic literature... ..., diagnostics, research tools, and/or technological... ...an experienced Principal Scientist to help establish and... ...multidisciplinary teams, senior leadership, and...PrincipalSeniorLocal area
Synolo Therapeutics
Cambridge, MA15 days ago $109.2k - $273k
...strategic epidemiology support for clinical development and drug safety... ...and conducting observational research studies, assessing evidence... ...development programs. The Senior Epidemiologist will collaborate... ...in Inflammation and Immunology therapeutic areas.Knowledge of...SeniorFull timePart timeImmediate startRemote workWorldwide$160k - $235k
...Sr. Scientist/Principal Scientist, Translational Research and Clinical Biomarkers (Immunology) Boston, MA Salary Band: $160,000-$235,000 Location: Downtown Boston, MA Position Summary Antares Therapeutics is seeking to add an enthusiastic and highly motivated...PrincipalSeniorAntares Therapeutics
Boston, MA21 hours ago- ...therapeutic areas including immunology, oncology and... ...accomplished and experienced Scientist to lead the Immune... ...for rheumatological, dermatological, gastroenterological... ...discovery immunology research. Highly... ...reports, peers, and senior leadership Establish...PrincipalSeniorFull timeWork experience placementLocal area
- ...****@*****.*** are seeking a highly skilled Scientist to join our Biologics Discovery team and lead antibody... ...in Protein Engineering, Molecular Biology, Biochemistry, Immunology, Cancer Biology, or a closely related field, with 2+ years of...PrincipalSenior
$137k - $215.27k
...knowledge.Job DescriptionAbout the role:The Pharmacovigilance Scientist, Senior Scientist ensures regulatory compliance and safety of Takeda... ...independently, providing critical analysis* Experienced in clinical development, contributing to the strategic planning and...PrincipalSeniorMinimum wageTemporary workLocal area$176.2k - $277.3k
...Drug Safety (NDS) on discovery research teams and in scientific and... ...focused primarily on immunology and oncology. This position... ...execution, and for the non-clinical safety sections of regulatory... ...experience as a non-clinical safety scientist (e.g. Toxicology, Pathology...PrincipalFull timeFor contractorsLocal areaWorldwideFlexible hours$115k - $215k
Who we are:Kymera is a clinical-stage biotechnology... ...degrader into the clinic for immunological diseases, Kymera is... ...Development:Drive TPD research programs through... ...recommendations to project teams, senior leadership, and... ..., solutions-oriented scientist with the ability to manage...PrincipalSenior- Orna Therapeutics, Inc. seeks a Senior Principal Scientist to drive analytical characterization of circular RNA and lipid nanoparticle therapeutics, focusing on mass spectrometry. You will collaborate with Platform Science, Discovery, and CMC to advance method development...PrincipalSenior
- UCB in Cambridge, MA is seeking a Senior Principal Scientist to lead translational biology drug discovery with emphasis on muscle biology. You will shape in vitro and in vivo models and develop cellular and biochemical assays for early programs across multiple neuromuscular...PrincipalSenior
$126k - $234k
Job Description Summary#LI-Hybrid Internal Title: Principal Scientist II or Senior Principal ScientistLocation: Cambridge, MANovartis is a leader in... ...antibody-xRNA conjugates, from discovery through clinical translation. In this role, you will partner with multi-disciplinary...PrincipalSeniorFull time$143k - $214.5k
...are seeking an innovative and strategic Principal Scientist, Molecular Cloning Technologies to lead... ...cloning strategy supporting Terrana's research and platform development efforts.Own the... ..., findings, and recommendations to senior leadership. PROFESSIONAL EXPERIENCE & QUALIFICATIONS...PrincipalSenior- Job DescriptionVertex is seeking an accomplished Senior Principal Scientist with proven record of developing, testing and deploying scientific... ...collaborative position at the intersection of computational sciences, research teams, and Digital Technology & Engineering.This is a...PrincipalSeniorFull timeSummer workRemote workFlexible hours2 days per week3 days per week
$148.5k - $214.5k
Job title: Senior Principal Scientist/Principal Scientist, Real-World Evidence & Disease GenomicsLocation... ...immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs... ...ability to engage meaningfully with clinical and disease area experts Strong...PrincipalSeniorFull time$146k - $236k
...advances in AI, machine learning, and data to accelerate fundamental research and create a portfolio of AI-first companies. As part of... ...with strong knowledge of physiology, molecular biology, and immunology Demonstrated expertise building mechanistic models for drug development...PrincipalSenior- ...them into scientifically rigorous AI co-scientists that enhance compound design, knowledge... ...scientific innovation across Discovery Research.Lead Platform Strategy, Adoption, and Responsible... ..., engineers, data scientists, and senior leaders across a matrixed organization....PrincipalSeniorFull timeSummer workRemote workFlexible hours2 days per week3 days per week
$214.1k - $337k
Job DescriptionSenior Principal Scientist - Boston, MAOverviewWe are seeking a Senior Principal Scientist to provide scientific and strategic leadership for mass... ...pharmaceutical, biotechnology, or closely related research setting; MS and 15+ years of experience; OR BS and...PrincipalSeniorFull timeFor contractorsLocal area$119.7k - $222.3k
...strategies to transform clinical pharmacology support... ...including oncology, immunology, cardiovascular renal... ...candidates across Research Development and Commercial... ...to be considered for Principal Scientist II. 4+ years of... ...to be considered for Senior Principal Scientist.Extensive...PrincipalSeniorFull time- ...Our lead program is in Phase 2 clinical trials, currently being... ...cell engagers, particularly in immunologically "cold" tumors. We're looking for a Senior Scientist with deep in vitro immunology... ...passionate, involved, and cutting-edge Research Team Exposure to pioneering...SeniorFull timeTemporary workWork at officeFlexible hours
$169.8k - $355.4k
...role, you will have an opportunity to work with teams of applied scientists and engineers to deliver high quality computer vision models... ..., and image processing Proven track record of leading research and development projects Strong understanding of machine learning...PrincipalSeniorTemporary workFlexible hoursOracle
Boston, MA1 day ago$138.6k - $257.4k
...Biomarkers group within Oncology Translational Research at Novartis Biomedical Research is seeking an accomplished Imaging Scientist to join the Image Analysis team in... ...supporting oncology drug discovery or early clinical development with image-based biomarker strategies...PrincipalSeniorFull time- As a Senior Scientist Immunology overseeing the design and execution of in vitro and in vivo mechanistic, proof-of-concept and safety studies, provide... ...in drug development in biotech or pharma setting, with research experience in autoimmune diseases.· Demonstrated...Senior
$150.5k - $245.5k
...medicines for people with serious diseases. We are seeking a Senior Manager to join our Clinical Sciences team, supporting our Immune/Inflammatory... ...requirements Strong medical writing skills and clinical research methodology expertise Experience in Immune/...SeniorWorldwide$126k - $181.5k
...Agriculture..Position Summary:We are seeking a highly motivated Senior Scientist of Immunology with expertise in T cell biology and in vivo CAR-T... ...scientific and technical expertise, and experience with pre-clinical disease models, scientific curiosity, and the desire to...Senior$120k - $165k
...the Danaher Business System which makes everything possible.Principal Clinical Scientist. This role is responsible for clinical trial strategies... ...or a related field with 9+ years of experience in clinical research, specifically with significant experience in US and/or EU...PrincipalFull timeImmediate startRemote workWork from homeFlexible hours$120k - $180k
...organization plays an important role in advancing clinical development through biomarker research, assay development, and cross-functional... ...SummaryVertex is seeking a strategic, hands-on Biomarkers Senior Research Lab Scientist to develop and optimize biomarker assays for...SeniorFull timeSummer workFlexible hours$100k - $181.5k
..., motivated, and highly collaborative Scientist/Senior Scientist to join our Translational Sciences... .... The position supports translational research and immunological activities aimed at bridging the gap between early research and clinical development. This role will be...Senior$145k - $161k
...areas of focus: hematology, immunology & oncology, liver and lung.... ...biology and a clearly defined clinical development and regulatory... ...exceptionally driven, discovery-minded Senior Scientist to join our Platform... ...to other platform-level research challenges. Unlike most industry...SeniorFull timeTemporary work$118k - $178k
...setting new benchmarks for biotechnological research. Our collaboration combines... ...breakthroughs in cell-based therapies and immunology. Here, your scientific passion will drive... .... We are seeking an experienced Senior Scientist, In Vivo Pharmacology to join a multidisciplinary...SeniorFull timeTemporary workWork at officeFlexible hours3 days per week- Bristol Myers Squibb seeks a Principal Scientist, Computational Biology in Cambridge, MA to join the Neuroscience, Immunology, and Cardiovascular discovery team within IPS. You will apply advanced computational methods to multi-omics and single-cell data to drive early...Principal
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Principal Scientist, Clinical Research - Immunology/Dermatology. Be the first to apply!
Related searches
- pharmacovigilance scientist Boston, MA
- regulatory scientist Boston, MA
- scientist biology Boston, MA
- applied scientist Boston, MA
- health scientist Boston, MA
- safety scientist Boston, MA
- pharmaceutical scientist Boston, MA
- deep learning scientist Boston, MA
- fermentation scientist Boston, MA
- cell culture scientist Boston, MA