Senior Principal Scientist, Immune Cell Depletion Discovery Group, Immunology Discovery Research
AbbVie Inc.
Company Description
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube.
Job Description
The Immunology Discovery Therapeutic Area is seeking an accomplished and experienced Scientist to lead the Immune Cell Depletion Group within the Immune Reset Therapeutics Discovery team based in Cambridge MA. In this role you will lead a multidisciplinary team of highly talented scientists with experimental, technical and scientific expertise in cellular depletion approaches. The candidate should have a demonstratable track-record in this scientific discipline alongside a strong knowledge of preclinical drug discovery spanning target discovery / validation through to GLP toxicology phases. The ability to effectively collaborate and deliver results across multi-disciplinary line functions both internally and with external leading experts is required. Proven expertise leading preclinical drug discovery programs leveraging cellular depletion approaches in autoimmune disease is an advantage. Applicants should have a strong publication record and have proven experience in leading (managing) & developing bench-based scientists.
Key Responsibilities:- Lead the Immune Cell Depletion Group within Immunology Discovery. Responsible for refining the strategy and biology focus within this area to support and advance the portfolio
- Provide biology expertise to internal teams that helps pave the way for next-generation therapies that leverage cell depletion approaches to develop next generation therapies for rheumatological, dermatological, gastroenterological and respiratory diseases
- Key member of the Immune Reset Therapeutics Discovery Leadership Team, to support advancement of Immune Tolerance biology into the drug discovery pipeline
- Proven experience in managing, growing and developing highly talented scientists
- Drive performance by Leading from the Bench. Including the ability to design and execute on key experiments to inform decision-points (GO / NO-GO) at critical stages of projects
- Proven track record of leading and influencing early to late-stage discovery programs
- Deep immunology expertise, with emphasis on understanding how cell depletion approaches can potentially raise the treatment ceiling for patients with autoimmune disease
- Help develop and execute a strategy in alignment with functional goals and key scientific objectives in discovery immunology research.
- Highly collaborative, team-oriented, and considerate of the needs of others
- Strong interpersonal skills and ability to collaborate with diverse groups within the organization and external partners.
- Highly organized & self-directed, capable of leading multiple complex research programs in parallel.
- Excellent written and verbal communication is required as well as critical evaluation and data-driven decision making.
- Provide expert advice and share knowledge with direct reports, peers, and senior leadership
- Establish and manage external collaborations with leading research labs around the world. Includes attendance / presentation at conferences and submission of publications.
Qualifications
- 18 +(BS), 16+ (MS), or 10+ (PhD) years of related work experience in academia, biotech or pharma
- Extensive experience in Immunology drug discovery within a high-caliber research environment with 6+ years of related work experience in biotech or pharma
- Ability to create an inclusive environment where diverse ideas, viewpoints and backgrounds are valued. Willingness and ability to lead inclusively and demonstrate a commitment to listen and consider all points of view
- Ability to work, influence, lead and deliver results in cross-functional teams
- Excellent written, presentation and interpersonal communication skills. Ability to be effective in a highly collaborative environment.
Key AbbVie Competencies:
- Builds strong relationships with peers and cross functionally with partners outside of the team to enable high performance.
- Learns fast, grasps the “essence” and can change course quickly where indicated.
- Raises the bar and is never satisfied with the status quo.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of thisposting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location,and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our long-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission,incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless anduntil paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
- ...therapeutic areas including immunology, oncology and... ...The Immunology Discovery Therapeutic Area... ...accomplished and experienced Scientist to lead the Immune Cell Depletion Group within the Immune... ...immunology research. Highly... ...reports, peers, and senior leadership Establish...PrincipalSeniorFull timeWork experience placementLocal area
- ...therapeutic areas including immunology, oncology and... ...The Immunology Discovery Therapeutic Area... ...accomplished and experienced Scientist to lead the Immune Cell Depletion Group within the Immune... ...immunology research. Highly... ...reports, peers, and senior leadership Establish...PrincipalSeniorWork experience placementLocal area
$80.3k - $131.1k
...highly motivated and innovative Senior Associate Scientist to join our discovery research team at Regeneron Cell Medicines. You will be performing immunological functional assays for analyzing genetically... ...functional assays to assess immune cell activation, anti‑tumor...Senior$80.3k - $131.1k
...highly motivated and innovative Senior Associate Scientist to join our discovery research team at Regeneron Cell Medicines. You will be performing immunological function assays for analyzing genetically... ...functional assays to assess immune cell activation, anti‑tumor...Senior$130.8k - $209.4k
...RoleThe Therapeutics Research group at Moderna is... ...highly motivated Senior Scientist to implement scalable... ...platforms for T cell repertoire... ...antigen-specific TCR discovery and functional validation... ...in T cell immunology, antigen-specific... ...complex immune profiling results...SeniorPermanent employmentFull timeWork at officeWork from home$142.5k - $256.5k
...accomplished and highly motivated Principal Scientist to join the Antibody Discovery team within Therapeutics Research. Therapeutics Research... ...and antigen strategy, immunization and B cell discovery campaign design... ...Qualifications)PhD in immunology, molecular biology, biochemistry...PrincipalPermanent employmentFull timeWork at officeWork from home$98.7k - $183.3k
...SummaryBiomedical Research (BR) is the... ...We are seeking a Senior Scientist to bring deep molecular... ...high-impact drug discovery programs.Job... ...Discovery Biology group in Cambridge is seeking... ...last 2 years) in Cell Biology,... ...Ethics, Gene Therapy, Immunology, Machine Learning...SeniorFull time$100.5k - $145.17k
...Job title: Senior Scientist, Medicinal Chemistry, Integrated Drug Discovery Location: Cambridge, MA About the... ...meets bold, AI-powered research. In R&D, you’ll drive... ...understanding of the immune system – and innovative... ...chemistry and participate in group/lab responsibilities....Senior$286.9k
Job DescriptionSenior Principal Scientist (Senior Medical Director)... ...ImmunologyTranslational Medicine in our Research & Development... ...of preclinical discovery into compounds ready... ...a position in our group. Please note that... ..., with a focus on Immunology R&D, as well as clinical...PrincipalSeniorFull timeFor contractorsLocal areaWorldwideFlexible hours$126k - $181.5k
...of small molecule drug discovery. FL129 is developing a... ...a team of top-tier scientists to build this powerful... ...highly collaborative Senior Scientist to join FL12... ...experience adapting screens to cell- or surface-displayed... ...managing contract research organizations (CROs)....SeniorContract work- ...staffingfuture.comOverviewWe are seeking a highly skilled Scientist to join our Biologics Discovery team and lead antibody discovery efforts. We are... ...Protein Engineering, Molecular Biology, Biochemistry, Immunology, Cancer Biology, or a closely related field, with 2+ years...PrincipalSenior
$131k - $146k
...different tissues, organs and cell types. Prime Medicine is... ...areas of focus: hematology, immunology & oncology, liver and lung.... ...an exceptionally driven, discovery-minded Scientist to join our Platform Technology... ...to other platform-level research challenges. Leading discovery...Full timeTemporary work$148.5k - $214.5k
Job title: Senior Principal ScientistLocation:... ...Senior Principal Scientist to spearhead... ...expansion of our mast cell disorders Research & Development... ...and related immune disorders in the... ....Drive early discovery initiatives by... ...biology, hematology, immunology, or related...PrincipalSeniorFull time$119.7k - $222.3k
...Experience in late discovery into clinical... ...and/or cell therapies across... ...including oncology, immunology,... ...candidates across Research Development and... ...considered for Principal Scientist II. 4+ years of... ...considered for Senior Principal Scientist... ...:The Novartis Group of Companies...PrincipalSeniorFull time$98.7k - $183.3k
...Biomedical Research (BR) is the innovation... ...patients. We are seeking a Senior Scientist to bring deep molecular... ...contributing to high-impact drug discovery programs. About the... ...Discovery Biology group in Cambridge is seeking... ...within last 2 years) in Cell Biology, Molecular...Senior$154.4k - $242.55k
...DescriptionJoin Takeda as a The Senior/Principal Scientist, Analytical Cell Line Engineering and... ...performing scientific research, development, and... ...at the interface between Discovery, Global Biologics, Analytical... ..., Biochemistry, Immunology, or a related discipline...PrincipalSeniorMinimum wageTemporary workLocal areaShift work- As a Senior Scientist Immunology overseeing the design and execution of in vitro... ...and technical expertise in immune cell biology, and support... ...precision immunology into new discovery programs. · Play a key team... ...biotech or pharma setting, with research experience in autoimmune...Senior
- ...Job Description Senior/Principal Scientist, MPN Biology,... ...PharmaEssentia Innovation Research Center (PIRC) is... ...-conjugates, cell-based therapies... ...to late discovery and into first in... ...hematology, oncology and immunology, with one... ...conferences and working groups. • Cross-...PrincipalSeniorContract work
$286.9k
...Senior Principal Scientist (Senior Medical Director) Translational Medicine, Immunology Translational Medicine in our Research & Development Division is responsible for planning and managing... ...benchtop science of preclinical discovery into compounds ready for assessment...PrincipalSeniorFor contractorsWork at officeRemote workWorldwideMonday to FridayMonday to ThursdayShift work3 days per week$115k - $215k
...into the clinic for immunological diseases, Kymera... ...:Drive TPD research programs through... ...biological matrices (e.g. cells, tissues,... ...to project teams, senior leadership, and external... ...that inform discovery, translational, and... ...-oriented scientist with the ability...PrincipalSenior$148.5k - $214.5k
Job title: Senior Principal Scientist/Principal Scientist, Real-World Evidence &... ...help shape the future of drug discovery and development across... ...immunoscience meets bold, AI-powered research. In R&D, you’ll drive... ...deep understanding of the immune system - and innovative pipeline...PrincipalSeniorFull time$98.7k - $183.3k
Summary LI#-Onsite (Lab Based) Internal Title: Senior Scientist II Location: Cambridge This role is based in... ...II in our Translational Medicine Drug Disposition Discovery Bioanalytical group, you will join a dynamic and high-performing team at the...SeniorLocal areaRelocation packageShift work$138.6k - $257.4k
...Oncology Pathology and Biomarkers group within Oncology Translational Research at Novartis Biomedical Research is seeking an accomplished Imaging Scientist to join the Image Analysis team in... ...biologyExperience supporting oncology drug discovery or early clinical development with...PrincipalSeniorFull time$160k - $235k
...enthusiastic and highly motivated scientist to its growing Translational Research team. The ideal candidate will have a strong background in immunology/auto-immune diseases, and have prior... ...across the organization with our Discovery, Data Science, and Clin Dev teams...PrincipalSenior- Reports to: Director, Discovery Research About Our Company: We are... ...high-impact targets in immunology. Our mission is to... ...and solutions-oriented cell biologist to join the discovery... ...role suits a hands-on scientist with deep experience in primary immune cell biology and...
$139.84k - $209.76k
...difference, there’s only one choice.Principal Scientist - In Vivo Expert, CVRI (Cardiovascular, Renal & Immunology) Bayer has an opening for a... ...-Renal In Vitro Research group based at the Bayer Innovation... ...disease modeling and drug discovery;Hands-on experience in setting...PrincipalLocal area- ...biology, DNA sequencing, immunology, and biologics drug discovery and development.... ...therapeutics, diagnostics, research tools, and/or technological... ...seeking an experienced Principal Scientist to help establish and advance... ...teams, senior leadership, and external...PrincipalSeniorLocal area
$122.25k - $176.58k
Job title: Principal Scientist, Lab Head, Integrative... ...targets through the discovery pipeline by... ...bold, AI-powered research. In R&D, you’ll drive... ...understanding of the immune system - and... ...therapeutic area, platform groups, and external... ...expertise in cell-based disease...PrincipalFull time$210.4k - $331.1k
...by partnering with Discovery Sciences and Late-Stage Clinical Research to translate... ...environment, the Immunology Clinical Operations... ...equivalent in level to a Senior Director position.... ...-coach’ to enrich group skillsets.... ...especially autoimmune or immune-mediated disorders...PrincipalSeniorFull timeFor contractorsLocal areaWorldwideFlexible hours$119.7k - $222.3k
...Experience in late discovery into clinical... ...and/or cell therapies across... ...including oncology, immunology,... ...candidates across Research Development and... ...considered for Principal Scientist II. 4+ years of... ...considered for Senior Principal Scientist... ...The Novartis Group of Companies...PrincipalSenior
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Principal Scientist, Immune Cell Depletion Discovery Group, Immunology Discovery Research. Be the first to apply!
- scientist Cambridge, MA
- cell culture scientist Cambridge, MA
- lab scientist Cambridge, MA
- research scientist - biology Cambridge, MA
- r&d scientist Cambridge, MA
- applied scientist Cambridge, MA
- molecular biology scientist Cambridge, MA
- regulatory scientist Cambridge, MA
- scientist antibody discovery Cambridge, MA
- senior research scientist Cambridge, MA

