Senior/Executive Director, Clin Development

Senior Director/Executive Director, Clinical DevelopmentAvenzo Therapeutics, Inc. ("Avenzo" or "Company") is a clinical-stage biotechnology company focused on developing next-generation oncology therapies for patients. The Company was co-founded in 2022 by Drs. Athena Countouriotis and Mohammad Hirmand. Our team is passionate about and committed to advancing a pipeline of potentially differentiated targeted oncology programs that make a difference in the lives of people with cancer. The Company is headquartered in San Diego, California.Position SummaryReporting to the Vice President, Clinical Development, the Senior Director/Executive Director, Clinical Development will be responsible for providing critical input into the strategy, development, management, and implementation of clinical studies by closely working across the clinical organization; leading multi-disciplinary teams charged with guiding clinical development and subsequent regulatory submissions.Essential Job Functions and ResponsibilitiesLead the development of clinical study protocols, protocol amendments, study guides, protocol training materials, and other clinical study-related documents based on the global development planManage clinical proof of concept, pivotal studies, and regulatory submissionsProvide practical and overarching strategic guidance for preclinical and clinical programs, ensuring that the design, implementation, and conduct of the company's clinical studiesDeliver unambiguous data and information that allows for clear decision-making and advancement of its developmental effortsTake medical responsibility in data analysis and interpretation, reporting, and communication to ensure consistency and relevance of medical content and scientific messages across Clinical Study Reports, health authority briefing books, NDA/BLA submission documents, etc.Identify clinical trial sites; work closely with and support Clinical Operations in site relationship activities as requiredContribute to operational aspects of study conduct and patient enrollment efforts, including participation in site training, initiation and activation, and subsequent site engagement activitiesMaintain focus on robust study conduct and quality data generationDemonstrate the ability to develop unique and innovative clinical strategies to significantly shorten the development cycle in the face of an evolving regulatory landscapeClinical development lead for assigned development programs and represents the program to executive leadership and study team membersSupport the recruitment/screening/selection of investigators in collaboration with Clinical Operations; ensure that Good Clinical Practices (GCPs) are followedAuthor clinical reports upon completion or termination of studiesAccountable for preparing clinical portions of protocols, investigator brochures, medical reports, efficacy and safety summaries, scientific rationales, and benefit/risk ratiosProvide leadership in Health Authority interactions and the development of regulatory documentsAttend and present at investigator meetings and site initiation visits as applicableTake initiatives with investigator and KOL engagementPreferred QualificationsMD required, advanced medical or life sciences or a related area degree preferred with 12+ years of experience in the life sciences industry or an equivalent combination of academic and industry experienceOncology solid tumor clinical development experience is required10+ years of experience in clinical developmentProven track record of leading clinical development programs from early-phase trials through regulatory submissionsStrategic leadership skills with the ability to inspire, mentor and manage cross-functional teamsExcellent communication and interpersonal skills, with the ability to collaborate effectively with internal and external stakeholdersStrong analytical and problem-solving abilities, with a strategic mindsetThis position requires periodic/regular travel, including up to 15 percentage of work time, which may include overnight travelPhysical Demands and Work EnvironmentPhysical Demands:Constant or continuous use of a computer keyboard, monitor, and mouse to perform a variety of tasksConstant or frequent sitting, standing, or walkingMay lift and/or move objects of various weightsWork Environment:Remote: Home office; expected to travel to and work from the Company's headquarters in San Diego from time to timeSan Diego-based: On-site requirement (Monday through Thursday)Noise level in the work environment is usually moderateFast-paced, time sensitive environment with frequently changing prioritiesHandle multiple projects simultaneouslyReasonable accommodations may be provided to enable qualified individuals with disabilities to perform the essential functions of the position.Salary RangeThe salary range for this position for a Senior Director is $339,000 to $361,000 per year and for an Executive Director $344,000 to $366,000 per year. The final pay offered to a successful candidate will be dependent on several factors that may include, but are not limited to, the type and years of experience within the job and the industry, education, and skills and certifications.BenefitsProvided they meet all eligibility requirements under the applicable plan documents, employees (and their eligible dependents) will be eligible to enroll in group healthcare plans that offer medical, dental, vision, and basic life and AD&D insurance. Additional benefit programs include short-term and long-term disability insurance, flexible spending accounts, health savings accounts, and voluntary insurance programs, including voluntary life, AD&D accident, and critical illness. Employees will also be able to enroll in the Company's 401(k) plan. In addition, employees will accrue 10 hours of paid vacation time every month and accrue 1 hour of paid sick leave for every 30 hours worked. Employees also enjoy 17 paid holidays each calendar year, including a winter closure, subject to applicable Company policies. All benefits are subject to the terms and conditions of the applicable plan documents and Company policies, which may be amended from time to time.Other CompensationThe hired candidate will be eligible to receive an annual discretionary bonus and an equity award, subject to the terms of the applicable employment agreement, plan documents, and Company policies.Applications for this position are anticipated to close on June 30, 2026. For more information about this posting, please contact View email address on click.appcast.io Employment OpportunityAvenzo is committed to providing equal employment opportunities to all employees and applicants without regard to an individual's actual or perceived protected characteristic or characteristics, or any combination of protected characteristics including race (including traits associated with race, such as hair texture and protective hairstyles, including braids, locks, and twists), ethnicity, religion, religious creed (including religious dress and grooming practices), color, sex (including childbirth, breast feeding, and related medical conditions), gender, gender identity or expression, sexual orientation, national origin, ancestry, citizenship status, uniformed service member and veteran status, marital status, pregnancy, age (40 and over), protected medical condition (including cancer and genetic conditions), genetic information, disability (mental and physical), reproductive health decision-making, medical leave or other types of protected leave (requesting or approved for leave under the Family and Medical Leave Act or the California Family Rights Act), the employee or their family member's status as a victim of a qualifying act of violence, political activity or affiliation, use of cannabis off the job and away from the workplace, association with an individual who has, or is perceived to have, a protected characteristic or characteristics, or any combination of protected characteristics, or any other protected status in accordance with all applicable federal, state, and local laws.Notice to Search Firms/Third Party AgenciesAvenzo does not accept unsolicited resumes from recruiters, employment agencies or search firms without a valid, executed search agreement in place.