Senior Scientist: High-Throughput Protein Design for Targets
BioSpace
Amgen is seeking a Senior Scientist in Experimental Protein Design for Target Discovery in South San Francisco. The role focuses on building and leading high‑throughput platforms to generate minibinders and antibodies from computational designs, with emphasis on de novo binder validation and library development. You will collaborate with molecular biology teams to establish production workflows, format binders into multispecific modalities, and interpret data to accelerate early‑stage #J-18808-Ljbffr BioSpace
- Senior Scientist Experimental Protein Design for Target Discovery What you will do In this vital role you will build and lead high-throughput platforms for binder generation, translating computational protein designs into experimentally validated minibinders and antibodies...SeniorFlexible hours
- ...Therapeutics, Inc. is seeking a Senior Scientist in South San Francisco to... ...transforming computational protein designs into validated binders and... ...include developing high-throughput platforms to generate and validate new binders for target discovery and therapeutic innovation...Senior
$150k - $170k
...development of generative AI models to design protein and antibody therapeutics, enabling the... ...against historically hard‑to‑drug molecular targets. It is also developing foundation models... ...junior scientific staff to foster a high‑performing and collaborative team. Manage...SeniorFlexible hours$136k - $170k
...generative AI models to design protein and antibody therapeutics... ...historically hard-to-drug molecular targets. It is also developing... ...an exceptional and highly motivated Senior Scientist to architect and lead our... ...discoveries through high-throughput functional genomics. You...SeniorFlexible hours- Amgen in South San Francisco, CA is seeking a Senior Scientist, Membrane Protein Biochemistry to join Discovery Protein Science. You will design recombinant production strategies for membrane proteins, purify targets with rigorous analytical characterization, and contribute...Senior
- Insitro is seeking an Associate Scientist III in South San Francisco to develop quality control metrics and conduct... ...degree in Biotechnology and experience in experimental design, with a focus on medium/high-throughput screening. Qualified candidates will have expertise...SeniorFlexible hours
- Position Title: Scientist I, Protein Purification & Expression Nurix Therapeutics... ..., and commercialization of targeted protein degradation... ...frontier in innovative drug design aimed at improving treatment... ...notebook systems. Responsibilities Highly proficient in maintaining...
- Xaira Therapeutics in the San Francisco Bay Area is seeking a PhD‑level protein engineer to lead the design, engineering, production, and characterization of therapeutic proteins and antibodies. You will optimize developability, format, and biophysical properties in a hands...Senior
- ...single-cell transcriptomic screens, turning high-dimensional, complex gene expression... ...enabling us to confidently prioritize the best targets and interventions.The Destination:Gordian... ...discussions that strengthen experimental design, and make time to connect over weekly...SeniorAgency workDay shift
$170k - $212k
...company developing novel targeted therapies for patients... ...RAS(ON) inhibitors designed to suppress diverse oncogenic... ...variants of RAS proteins, including... ...Opportunity The DMPK Scientist will be a key member of... ...Skills, and Education A highly motivated individual with...Senior$162k - $196k
...discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for... ...Nurix Therapeutics seeks an experienced Senior Scientist to join the Analytical Development and...SeniorContract work$110k - $138k
...Principal Associate Scientist, BiologySouth San Francisco, California... ...of generative AI models to design protein and antibody therapeutics, enabling... ...hard-to-drug molecular targets. It is also developing foundation... ...and pharmacology to generate high-quality data that supports...Flexible hours$125k - $180k
...Clinical Development Scientist/Senior Clinical Development Scientist TenvieTherapeuticsis... ...CNS-penetrant NLRP3 inhibitor targeting cardiometabolicand... ...a scientifically rigorous and highly collaborative Clinical Scientist to support the design and execution of early clinical...SeniorInterim roleLocal areaRemote work$124k - $155k
...development of generative AI models to design protein and antibody therapeutics,... ...hard-to-drug molecular targets. It is also developing... ...London. About the Role As a Scientist II on Xaira's Genomics Core team within the High Throughput Biology organization, you will...Flexible hours$124k - $155k
...generative AI models to design protein and antibody... ...hard-to-drug molecular targets. It is also developing... ...and turn campaigns into high-quality datasets that... ...: mentoring associate scientists, setting technical standards... ...these assays to higher-throughput and automated formats....Flexible hours- Amgen in South San Francisco is seeking a Scientist, Membrane Protein Biochemistry to design strategies for recombinant production of polytopic membrane protein targets and purify MPs with detailed analytical characterization in an onsite lab. The role offers opportunities...
- ...discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for... ...and execute analytical strategies for high‑throughput DAC screening, establish quality criteria...
$71.25k - $187k
...work, executing experiments on programs designed by the project lead, generating decision-... ...molecular and cellular assays to interrogate target biology, including panel design, FACS... ...acquisition, and analysis in FlowJo), and protein detection methods such as Western blotting...SeniorFlexible hours$90k - $210k
...SummaryCellares is seeking an innovative and highly motivated Senior Scientist with expertise in cell therapy... ...focus of this position is to design, coordinate, execute and analyze cell... ...manufacturing process in a flexible and high-throughput platform that delivers true walk-...SeniorFull timeFlexible hours$170k - $240k
...lead longer and healthier lives. Calico’s highly innovative technology labs, its commitment... ...Calico is seeking a machine learning research scientist to develop innovative machine learning algorithms to model and design proteins. This person will work with a team of...Senior- ...sector is seeking a skilled scientist to join their team. This exciting role involves designing and performing critical assays... ...to evaluate mRNA delivery and protein expression in mammalian cells... ...opportunity to engage in high-throughput workflows and collaborate with...
- Preventive is seeking a Scientist/Senior Scientist to lead genomic analysis across wet-lab experiments... ...and computational pipelines. You will design, execute, and analyze ultra-low-input... ...characterization and safety/off-target profiling. Responsibilities include developing...Senior
- ...Electrochemistry, Electrocatalysis, and Microarray Electrosynthesis to drive massively parallel DNA synthesis on high-density chip arrays. You will design high-throughput experiments, optimize electrochemical pathways, and collaborate with biochemists and hardware engineers to...Senior
- Genentech is seeking a Scientist 3 to advance target discovery through cutting-edge genomics and molecular engineering. You will design and apply functional genomics read-outs, model systems, and imaging to study immune-mediated diseases at scale. The role emphasizes technology...Senior
- Genentech is seeking a Scientist 3 to execute cutting-edge single-cell and functional genomic... ...study cancer biology. You'll perform high-throughput screens, deploy single-cell profiling... ...to reveal molecular mechanisms and targets for therapy. The role requires a PhD in...Senior
- A bio-innovation firm in San Francisco is seeking a Machine Learning Scientist to lead research initiatives and innovate protein design methodologies. The ideal candidate will drive research on AI applications in protein design, with responsibilities including project...Senior
- ...Innovation Group is seeking a Senior Scientist I to join a talented... ...from experimental design through execution and... ...of recombinant protein expression to improve... ...out at the bench with a high degree of independence... ...engineering to knock in/out target genes, and in vitro...SeniorTemporary work
$142.52k - $192.82k
Senior Scientist, Membrane Protein Biochemistry page is loaded## Senior Scientist, Membrane... ...(but not limited to) the design of strategies for... ...polytopic membrane protein (MP) targets and their purification with... ..., ethical, committed and highly accomplished people who respect...SeniorFlexible hours$129k - $203.1k
...a curious and collaborative Senior Scientist for our growing Translational... ...modeler and scientist who designs and executes analyses, with... ...with a focus on biologics, protein therapeutics, and peptides.... ...established and novel therapeutic targets; Collaborate across our...SeniorFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work- ...development, and commercialization of targeted protein degradation medicines, the... ...frontier in innovative drug design aimed at improving treatment... ...Therapeutics is seeking a Scientist to lead bioanalytical... ...species, and catabolites Apply high-resolution mass spectrometry...Contract work
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Scientist: High-Throughput Protein Design for Targets. Be the first to apply!
- scientist ii South San Francisco, CA
- scientist 1 South San Francisco, CA
- image scientist South San Francisco, CA
- downstream processing scientist South San Francisco, CA
- qc scientist South San Francisco, CA
- research scientist South San Francisco, CA
- analytical scientist South San Francisco, CA
- research scientist - biology South San Francisco, CA
- genomics scientist South San Francisco, CA
- quality control scientist South San Francisco, CA

