Sr-Scientist, Proteomics | South San Francisco, CA
$60 - $70 per hourHydrogen Group
Scientist - Proteomics & Mass Spectrometry
South San Francisco, CA | 12-month contract | Onsite | $60-70/hour
We are seeking an experienced Scientist to join a highly collaborative proteomics and mass spectrometry team within a cutting-edge R&D environment.
This is a hands-on laboratory role for someone who thrives in complex, multi-disciplinary research settings and enjoys solving challenging biological and analytical problems. The successful candidate will bring strong expertise in proteomics, biochemistry, and mass spectrometry-based workflows, alongside a detail-driven and organised approach to experimental work.
You will be involved in both standard and advanced proteomics techniques, including protein affinity workflows, immunoprecipitation, and enrichment strategies for post-translational modifications. The team works across a broad range of biological research areas including disease biology, immune pathways, and technology development, supporting translational and early discovery programmes.
Key Responsibilities
- Prepare and process biological samples from tissues, cells, and biofluids for proteomics analysis
- Develop, optimise, and refine sample preparation workflows for protein profiling and biomarker discovery
- Operate, maintain, and troubleshoot HPLC systems, mass spectrometers, and associated bioanalytical instrumentation
- Analyse proteomics datasets and communicate findings to internal collaborators
- Present experimental results in group meetings and cross-functional scientific discussions
- Support ongoing assay development and research initiatives across multiple disease areas
Requirements
- PhD in proteomics, biochemistry, chemistry, molecular biology, chemical engineering, or a related discipline
- Strong hands-on experience in mass spectrometry-based proteomics
- Demonstrated experience in HPLC and/or LC-MS method development and optimisation
- Experience maintaining and troubleshooting analytical instrumentation (HPLC and mass spectrometers)
- Practical experience in proteomics sample preparation workflows
- Proficiency in data analysis using R and/or Python
- Strong attention to detail with excellent organisational skills
Desirable Experience
- Protein affinity workflows including immunoprecipitation
- Post-translational modification enrichment and analysis
- Laser capture microdissection (LCM)
- Histology-related sample handling (e.g. FFPE, cryosectioning)
Please apply with an updated copy of your resume to be considered.
Vacancy posted 10 hours ago
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