Research Associate II

Title: Research Associate II
Location: Lexington, MA
Pay $48.37/hr on w2

TOP SKILLS PER MGR:

• mammalian cell culture;
• cell-based assays;
• real-time PCRquantitative rea

Purpose
To provide technical laboratory research effort in support of multiple projects focused on expedited evaluation and the clinical translation of therapies.

Essential Functions:
siRNA drug candidate screening, hit identification, and lead optimization
Cellular and molecular biology methodologies, e.g., mammalian cell culture; in vitro screening; cell-based assays; RNA extraction and RT-qPCR
Analyze data and present the results in group meetings
Maintain clear experimental records in laboratory notebooks; write SOPs and other technical reports as needed
Work closely with research team members to quickly and effectively address critical questions related to the efficacy of our drugs
Review literature and provide insights to research directions, while predominantly making hands-on contributions to the research

Qualifications:
Master's in Cell and Molecular Biology or Pharmaceutical Sciences
4+ years of relevant drug discovery laboratory experience in industrial or academic environment is preferred
Experience in cellular and molecular biology is essential (e.g., mammalian cell culture, cell-based assays, quantitative real-time PCR)
Experience with primary human adipocytes and hepatocytes culture is preferred
Experience with advanced in vitro model systems including organoids and other 3D culture systems is highly preferred
Experience with RNAi and in vitro screening is preferred
Candidate must have strong oral and written communication skills, strong work ethics and demonstrated to be an effective contributor to group projects in a team-oriented environment
The ability to perform and interpret experiments reliably, and to advance projects aggressively towards defined goals is expected