Clinical Scientist

About Outpace Bio Outpace Bio is pioneering the future of cell therapy for solid tumors by harnessing unrivaled AI-powered protein design. Our mission is to program immune cells for enhanced function inside patients, overcoming key barriers such as poor tumor access, weak survival, antigen escape, and dose-related toxicity. By creating and integrating modular, plug-and-play technology assets, we are developing cell therapies with unprecedented efficacy, transforming how engineered T cells interact with cancer and the immune system to deliver life-changing outcomes. Our multidisciplinary team of scientists, engineers, coders, and cell therapy developers works at the cutting edge of computational protein design, synthetic biology, and immunology. Together, we are reimagining how cells function to unlock novel therapeutic possibilities. Located in Seattle’s vibrant biotech hub overlooking scenic South Lake Union, Outpace Bio is led by pioneers in computational protein design and engineered cell therapies. Our culture is built on a foundation of respect and inclusion, which are fundamental to how we collaborate to revolutionize cell therapy through groundbreaking innovation rooted in rigorous science. Our Commitment to Diversity At Outpace Bio, we believe that the highest performing teams include people from a wide variety of backgrounds and experiences. We are committed to cultivating an open, diverse, and inclusive culture for all employees. Recognizing that the best candidates do not always match all criteria of the job description, we encourage you to apply if you think you would be a good fit for the role and are inspired by our mission to cure disease by pushing the boundaries of biology. Our Momentum In August 2024, Outpace Bio secured an oversubscribed $144 million Series B financing, led by RA Capital Management and supported by a premier syndicate of life science investors. This funding accelerates our pipeline of programmed T cell therapies, including our lead candidate OPB-101, a mesothelin-specific chimeric antigen receptor (CAR) T cell enhanced by Outpace’s proprietary OUTSMART™, OUTLAST™, OUTSPACER™, and OUTSAFE™ technologies. OPB-101 is advancing toward IND clearance and first dosing in 2025 for patients with advanced platinum-resistant ovarian cancers. The Series B investment also supports the expansion of our pipeline, enabling us to develop additional transformative therapies leveraging our innovative plug-and-play technology platform. We are seeking a highly motivated and experienced Clinical Scientist to help lead our cross-functional teams designing and advancing programmed T cell therapies into the clinic. Reporting to the Senior Medical Director, the Clinical Scientist will be an essential contributor to the scientific, clinical, and operational scope of clinical development programs with an emphasis on study and program-specific activities. We’re looking for a scientist who thrives in dynamic environments and is passionate about Outpace’s mission to revolutionize cell therapy. If you’re a clinical scientist and clinical development professional eager to work on cutting-edge science with a collaborative team and grow your career, this could be the role for you. Key Responsibilities Serve as the study clinical scientist on oncology cell therapy trials to partner closely with the Senior Medical Director in the execution of the clinical development strategy for assigned asset(s), actively participating in study start-up activities, asset team meetings, safety monitoring committees, and coordination of patient enrollment and dosing with product manufacturing/delivery managed by technical operations and clinical operations. Conduct review of emerging clinical and medical data to ensure quality data; review and query data; present and discuss relevant data to appropriate teams and stakeholders. Collaborate on the preparation and review of clinical protocols and amendments and support the development of other critical study and regulatory documents including informed consent forms, investigator brochures, statistical analysis plans, regulatory documents, annual reports, and clinical study reports (CSRs). Support clinical development activities during implementation of the clinical database with CRO. Review risks, query resolution, and protocol deviations; support and assist in the development of publications, abstracts, and presentations. Develop effective collaborations with key internal and external partners, such as cross-functional team members, consultants, asset team leaders, and clinical trial site staff. Serve as a technical resource for clinical issues raised by internal and external collaborators, investigators, consultants and contractors. Participate in project teams to help implement clinical development and contribute to key milestones (e.g., start-up and delivery of POC trials). Required Qualifications Bachelor's degree or advanced degree (MSc, PharmD, MD, PhD) in Life Sciences, Pharmacology, or related field. Minimum of 3 years’ experience in conducting or supporting oncology/hematology clinical studies; experience in early phase development and/or cell therapy preferred. Excellent written and verbal communication skills. Experience with interpretation of clinical research results including safety and efficacy; familiarity with statistical principles desirable. Ability to think strategically and tactically with an interest in clinical research and drug development with a focus on delivering results and driving innovation. Ability to adapt and problem-solve in an agile, fast-paced, start-up, team-based matrix environment and function independently as appropriate; flexible to accommodate changes in team and project needs. Ability to handle multiple projects at a time and maintain strong attention to detail while understanding the higher-level strategy. Passion for developing complex, innovative medicines for solid tumors. Salary: $226,000 - $267,000 a year. Actual compensation is dependent upon current market data, experience, and pay parity at Outpace. Location: Remote - candidates based in CA, OR, or WA will be considered. Outpace Bio Total Rewards Full time employees and their eligible dependents may enroll in Outpace’s medical, dental, vision, life insurance, disability, flexible spending account, health savings account, commuter benefits, legal benefits, and 401k plan including an employer match. Employees may receive stock option grants outlined in the offer of employment and a performance bonus. Outpace offers flexible PTO, paid sick leave compliant with local requirements, fifteen paid holidays plus a winter shutdown, and a generous paid parental leave policy to all regular full‑time employees. Outpace Bio is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information, gender identity and expression, veteran status, or other non‑job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. Applicants must be authorized to work in the United States. If you are legally authorized to work in the United States now or in the future without any form of sponsorship, we encourage you to apply. #J-18808-Ljbffr Outpace Bio