Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Scientist, Integrated Computational and Experimental Inflammation Discovery

BioSpace

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Scientist, Integrated Computational and Experimental Inflammation Discovery What you will do Lets do this. Lets change the world. In this vital role, you will contribute to Inflammation discovery programs by personally designing and executing wet-lab studies and applying computational and AI-enabled approaches to analyze and integrate omics data. You will connect these insights with experimental findings to deepen our understanding of disease biology, prioritize therapeutic targets, and develop and test mechanistic hypotheses in the laboratory. Working with minimal supervision, you will manage defined program components, develop an area of scientific expertise, and communicate data-driven insights that help advance project decisions. Key Responsibilities Plan and coordinate defined project tasks and activities that support target identification, validation, and progression of Inflammation discovery programs. Design, execute, analyze, and interpret bench/wet lab studies to investigate disease mechanisms and test therapeutic hypotheses with scientific rigor and appropriate urgency. Apply computational, AI-enabled, and data-analytic approaches to generate mechanistic insights, refine experimental design, and integrate findings across data sources. Integrate experimental results with published literature, human genetics, clinical observations, and internal or external datasets to inform ongoing project design. Develop and optimize solutions to technical problems of advanced scope and complexity within an emerging area of expertise. Collaborate across functions and departments, contributing at the project-team level and building constructive relationships with wet-lab, computational, translational, and drug-discovery partners. Organize, interpret, document, and present project data and scientific recommendations within work groups, project teams, and internal scientific forums. Coach or guide others within the work group or project team where appropriate, and contribute to a collaborative culture of scientific curiosity, knowledge sharing, and operational excellence. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The researcher we seek is a Scientist with these qualifications. Basic Qualifications Doctorate degree OR Masters degree and 2 years of experience in Immunology, Cell Biology, Molecular Biology, Pharmacology, Biomedical Sciences, Computational Biology, Bioengineering OR Bachelors degree and 4 years of experience in Immunology, Cell Biology, Molecular Biology, Pharmacology, Biomedical Sciences, Computational Biology, Bioengineering Preferred Qualifications Demonstrated hands-on experience independently designing, executing, troubleshooting, and interpreting wet-lab experiments to investigate inflammation biology and validate therapeutic hypotheses. Strong grounding in inflammation and immunology, with the ability to translate computational insights into testable hypotheses and follow-up laboratory studies. Experience analyzing spatial transcriptomics data and/or integrating multimodal omics datasets to investigate disease mechanisms and inform target discovery. Hands-on proficiency in Python or R for omics data analysis and visualization, including the ability to critically evaluate analytical methods and outputs from AI-enabled tools and computational workflows. Ability to work independently and manage defined project components. Strong scientific communication and cross-functional collaboration skills. What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In Addition To The Base Salary, Amgen Offers a Total Rewards Plan, Based On Eligibility, Comprising Of Health And Welfare Plans For Staff And Eligible Dependents, Financial Plans With Opportunities To Save Towards Retirement Or Other Goals, Work/life Balance, And Career Development Opportunities That May Include A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. careers.amgen.com #J-18808-Ljbffr BioSpace

Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Scientist, Integrated Computational and Experimental Inflammation Discovery in South San Francisco, CA vacancy
  • $131.03k - $177.27k

    Senior Scientist, Integrated Computational and Experimental Inflammation Discovery Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses... 
    Suggested
    Flexible hours

    Amgen Inc.

    South San Francisco, CA
    3 days ago
  • Amgen seeks a Senior Scientist to advance Inflammation discovery by leading experimental and computational activities within project teams. You will iterate between bench work and computational workflows, coordinating efforts across disciplines to deliver data-driven recommendations... 
    Suggested

    BioSpace

    South San Francisco, CA
    3 days ago
  • Amgen is seeking a Scientist for Integrated Computational and Experimental Inflammation Discovery. The role focuses on planning and coordinating inflammation discovery tasks, performing bench and computational studies, and applying AI-enabled analyses to refine therapeutic... 
    Suggested

    Amgen

    South San Francisco, CA
    2 days ago
  • Amgen in South San Francisco is seeking a Scientist, Integrated Computational and Experimental Inflammation Discovery. In this role you will design and execute wet-lab studies and apply computational and AI-enabled approaches to analyze omics data, advancing inflammation... 
    Suggested

    BioSpace

    South San Francisco, CA
    2 days ago
  • Amgen seeks a Senior Scientist to lead integrated computational and experimental inflammation discovery. You will advance inflammation programs by generating rigorous evidence, coordinating teams, and applying AI-enabled analytics to deepen disease understanding and guide... 
    Suggested

    Amgen Inc.

    South San Francisco, CA
    3 days ago
  • $201.3k - $373.8k

     ...Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche...  ...(AI) to assist our scientists in both pRED and gRED...  ...machine learning methods integrate seamlessly into...  ...computational methods and experimental biologyUnderstanding of... 
    Local area
    Worldwide

    Genentech

    South San Francisco, CA
    2 days ago
  • $167.4k - $310.8k

     ...Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche...  ...(AI) to assist our scientists in both pRED and gRED...  ...conducted. Our vision is to integrate artificial...  ...with computational and experimental scientists and researchers... 
    Full time
    Local area
    Worldwide
    Relocation package
    Shift work

    Genentech

    South San Francisco, CA
    4 days ago
  • $167.4k - $310.8k

     ...Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche...  ...(AI) to assist our scientists in both pRED and gRED...  ...You own the end-to-end integrity of large-scale...  ...excellence and rapid experimentation.As a Principal ML Scientist... 
    Full time
    Local area
    Worldwide
    Relocation package

    Genentech

    South San Francisco, CA
    4 days ago
  •  ...areas –Oncology, Inflammation, General Medicine,...  ...your career. Sr. Scientist – Bioinformatics, Computational Biology,...  ...infrastructure to support the Discovery Proteomics Group....  ...to understand experimental and discovery needs...  ...platforms for data integration and mining, and utilize... 
    Flexible hours

    Amgen SA

    San Francisco, CA
    1 day ago
  • $170k - $230k

     ...heart of Gordian's discovery efforts. In this role...  ...frameworks the rest of the computational team builds on....  ...through hands‑on experimentation and "pre-mortem" discussions...  ...of AI in the space, integrating the best tools into...  ...and experimental scientists as you are... 
    Agency work
    Remote work
    Day shift
    3 days per week

    Gordian Biotechnology

    South San Francisco, CA
    1 day ago
  •  ...several areas including computational biology,...  ...and are looking for scientists to join us on this mission...  ...as Singleton’s core discovery platform. As the company...  ...tissue-based validation experimental approaches; use experimental...  ...correction, and integration across platforms... 

    Singleton Bio

    South San Francisco, CA
    1 day ago
  •  ...Gordian Biotechnology is seeking a Principal Computational Biologist to shape how large-scale in vivo perturbation screens are analyzed...  ...field, 2+ years in industry, and deep experience in single-cell transcriptomics, ML, and data integration, with a track #J-18808-Ljbffr... 

    Gordian Biotechnology

    South San Francisco, CA
    1 day ago
  •  ...experienced and accomplished scientists and clinicians, a...  ...Associate Scientist, Computational Biology, to join our...  ..., and supporting the discovery of new therapeutic...  ...samples. Evaluate and integrate deep-learning...  ...questions and inform experimental design.   ~ Make scientific... 
    Local area
    Flexible hours

    Alector

    South San Francisco, CA
    24 days ago
  • $150.7k - $180.8k

    Senior Computational Scientist, AI for Protein Design and DiscoveryAbout the...  ...solutions for protein design, discovery, and characterization.You...  ..., machine learning, and experimental science, collaborating...  ...doDevelop algorithms that integrate protein sequences with NGS... 

    Twist Bioscience

    San Francisco, CA
    4 days ago
  •  ...Computational Biologist, Contractor/Consultant About...  ...closely with our wet-lab scientists to establish...  ...recommend improvements to experimental design and assay development...  ...including off-target discovery, validation, and...  ..., low-VAF mosaicism, integration sites, or other... 
    For contractors

    Preventive Services

    South San Francisco, CA
    1 day ago
  •  ...data is at the heart of Gordian’s discovery platform. As a Senior Computational Biologist, you’ll analyze and...  ...approaches - from multimodal reference integration to emerging foundation-model...  ...collaboration through hands‑on experimentation and “pre‑mortem” discussions... 
    Agency work
    Day shift
    3 days per week

    Gordian Biotechnology

    South San Francisco, CA
    2 days ago
  •  ...Biosciences, a precision oncology company in South San Francisco, seeks a Senior Principal Research Scientist in Computational Chemistry to advance small molecule discovery. You will lead design efforts, partner with medicinal chemists, and apply advanced computational... 

    IDEAYA Biosciences

    South San Francisco, CA
    5 days ago
  •  ...Associate Director, Human Disease Biology, Inflammation Research to advance disease biology with multi-omics and computational analyses. You will integrate human genetics, transcriptomics,...  ..., and contribute to target discovery and program prioritization within inflammation... 

    Amgen Inc. (IR)

    South San Francisco, CA
    5 days ago
  •  ...Biotechnology in South San Francisco is seeking a Principal Computational Biologist to shape how large-scale perturbation data informs...  ...computational team. You will apply deep ML and single-cell analytics, integrate multi-omics data, and collaborate with wet-lab groups to... 

    gordian-biotechnology

    South San Francisco, CA
    3 days ago
  • $144.9k - $269.1k

     ...Roche.Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research...  ...Intelligence (AI) to assist our scientists in delivering more innovative...  ...automation and AI agents.Analysis and integration of human genetic, single-cell... 
    Full time
    Local area
    Worldwide
    Relocation package
    3 days per week

    Genentech

    South San Francisco, CA
    5 days ago
  • $168.1k - $312.3k

     ...Roche.Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s...  ...Intelligence (AI) to assist our scientists in both pRED and gRED to deliver...  ...bridge computational methods and experimental reality—who understand both the... 
    Full time
    Local area
    Worldwide

    Genentech

    South San Francisco, CA
    2 days ago
  • $201.3k - $373.8k

     ...Roche.Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research...  ...Intelligence (AI) to assist our scientists in both pRED and gRED to deliver...  ...is conducted. Our vision is to integrate artificial intelligence and machine... 
    Full time
    Local area
    Worldwide
    Shift work

    Genentech

    South San Francisco, CA
    2 days ago
  • $201.3k - $373.8k

     ...Roche.Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s...  ...Intelligence (AI) to assist our scientists in both pRED and gRED to deliver...  ...experiments, including designing experimental details, writing reusable code,... 
    Full time
    Work experience placement
    Local area
    Worldwide
    Relocation package

    Genentech

    South San Francisco, CA
    5 days ago
  • $146.54k - $189.64k

     ...critical role in the discovery and development of life...  ...an Imaging Data Scientist to apply AI, machine...  ...requires strong Python, computer vision, and deep learning...  ..., fibrosis, and inflammation. This role partners closely...  ...each employee as an integral member of our company... 
    Full time
    For contractors
    Local area

    GILEAD Sciences

    San Mateo, CA
    3 days ago
  • $63.5k - $194.8k

    Computational Scientist, Lung Transplant Immunology — Lung Transplant Research...  ...potential for high-impact discovery with immediate...  ...lab studies innate immune inflammation, NK cell biology, airway epithelial...  ...air-liquid interface data • Integration of these data with... 
    Traineeship
    Immediate start

    University of California, San Francisco

    San Francisco, CA
    2 days ago
  •  ...deployed into pharma's drug discovery workflows, where scientists use them to solve the...  ...liver injury through an integrated data and agentic system...  ...major parts of Axiom’s computational mass spectrometry stack....  ...lab scientists to improve experimental design and debug assays.... 

    Axiom company

    San Francisco, CA
    1 day ago
  •  ...Senior Machine Learning Scientist, AI for Drug Discovery (Frontier Research) Aug 6, 2025 Link to job posting: Advances in AI, data, and computational sciences are transforming drug discovery...  ...experiments, including designing experimental details, writing reusable code,... 
    Worldwide
    Relocation package

    The International Society for Bayesian Analysis

    South San Francisco, CA
    5 days ago
  • $147.6k - $274k

     ...Roche. Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s...  ...Intelligence (AI) to assist our scientists in both pRED and gRED to deliver...  ...widely with computational and experimental researchers at Roche and with academic... 
    Local area
    Worldwide
    Relocation package

    F. Hoffmann-La Roche AG

    South San Francisco, CA
    1 hour ago
  • $165.3k - $206.6k

     ...programs. As a Principal Scientist at BeOne Institute,...  ...in the future Computer Skills Candidates are...  ...preferably in a drug discovery or pharmaceutical research...  ...ability to integrate chemistry with biological data and use experimental results to inform compound... 
    Hourly pay
    Local area
    Worldwide

    BeiGene

    San Carlos, CA
    4 days ago
  • $159.6k - $251.2k

     ...recruiting an Associate Principal Scientist to support our Molecular Discovery group located in South San...  ...workflow automation, or instrument integration. Strong experience with binding and...  ...into scalable workflows, define experimental plans, resolve complex technical... 
    For contractors
    Local area
    Relocation
    Visa sponsorship
    Flexible hours
    Shift work

    Merck & Co. Inc

    South San Francisco, CA
    13 hours ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Scientist, Integrated Computational and Experimental Inflammation Discovery. Be the first to apply!