Principal Computational Biologist — Target Discovery
gordian-biotechnology
Gordian Biotechnology in South San Francisco is seeking a Principal Computational Biologist to shape how large-scale perturbation data informs target prioritization and MOA exploration. You will define standardized analytical frameworks, work with disease experts on forward planning, and push methodological advances across the computational team. You will apply deep ML and single-cell analytics, integrate multi-omics data, and collaborate with wet-lab groups to ensure rigorous, translatable #J-18808-Ljbffr gordian-biotechnology
- ...Principal Computational Biologist Are you ready to own the strategy behind how Gordian turns large-scale... ...pipeline of therapeutic targets across chronic and age-related disease... ...transcriptomic data is at the heart of Gordian's discovery efforts. In this role, you'll set...PrincipalTargetDay shift
- Gordian Biotechnology is seeking a Principal Computational Biologist to shape how large-scale in vivo perturbation screens are analyzed and translated into therapeutic targets. You will define methods for perturbation data, partner with disease experts for forward screen...Target
- ...transcriptomic data is at the heart of Gordian's discovery efforts, and the company will succeed... ...us to confidently prioritize the best targets and interventions. The Destination... ...disease areas. Your mission as a Computational Biologist at Gordian is to leverage our in vivo...TargetAgency workDay shift
- ...scale transcriptomic data is at the heart of Gordian’s discovery platform. As a Senior Computational Biologist, you’ll analyze and help evolve our large-scale in... ...high-dimensional perturbational data into robust targeted hypotheses. You’ll bring creativity and technical...TargetAgency workDay shift3 days per week
- ...tissue to discover therapeutic targets in immunological and... ...in several areas including computational biology, immunobiology, in vitro... ...individual to join our team as a Principal Computational Scientist .... ...tissue model as Singleton’s core discovery platform. As the company’s...PrincipalTarget
$196k - $242k
...oncology company committed to the discovery, development, and commercialization... ..., potentially first‑in‑class targeted therapies aligned to the genetic drivers... ...seeking an accomplished Senior Principal Research Scientist in Computational Chemistry with significant pharmaceutical...PrincipalTargetTemporary workWork at officeLocal areaWork from home1 day per week$141.5k - $262.9k
...development and marketed products. This Principal Scientist role is intended for an entry... ...program advancement and decision-making from discovery and candidate selection through... ...program decisions. Anticipate potential target-, modality-, or mechanism-related safety...PrincipalTargetLocal areaRelocation package3 days per week- ...South San Francisco seeks a Senior Principal Research Scientist in Computational Chemistry with a strong industry... ...record to advance small-molecule discovery programs. You will lead design efforts... ...to drive decision-making across target identification, hit discovery, and...PrincipalTarget
$131.33k - $189.53k
...At Freenome, we are seeking a Computational Biologist to help grow the Freenome Computational Biology... ...DNA methylation data for biomarker discovery research. Experience in developing, applying... ...and additional information: The US target range of our base salary rate for new...TargetLocal areaRemote work$141.5k - $262.9k
...therapeutics spanning from drug discovery through clinical... ...solutions to address target safety assessments,... ...Systems (CIS) and Computational Toxicology—to... ...environments.Senior Principal Scientist: Ph.D. with... ...collaborating with computational biologists and predictive...PrincipalTargetFull timeLocal areaRelocation package$144.9k - $269.1k
...Roche.Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research... ...entries to Neuroscience department Target Assessment Portfolio and... ...equivalent experience after PhD (Principal Scientist). The ideal candidate will...PrincipalTargetFull timeLocal areaWorldwideRelocation package3 days per week$201.3k - $373.8k
...That’s what makes us Roche.Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early... ...learning into every stage of antibody discovery—from target assessment and design optimization to developability...PrincipalTargetFull timeLocal areaWorldwideShift work$188.28k - $270.38k
...Staff Computational Biologist Remote At Freenome, we are seeking a seasoned Staff Computational... ..., whole genome bisulfite sequencing, targeted sequencing, RNA sequencing, and... ...computational techniques for biological discovery and product development, preferably in...TargetLocal areaRemote work$164k - $205k
...Principal Scientist, Protein Engineering South San Francisco,... ...leveraging AI to transform drug discovery and development. The company... ...hard-to-drug molecular targets. It is also developing foundation... ...protein engineering with computational design. As a Principal Scientist...PrincipalTargetFlexible hours$35 - $39 per hour
JSG is seeking a Biologist (ARA) - II (Associate) for our client in... ...science, supporting target identification and validation... ...metabolic disorders, driving the discovery pipeline forward.Pay $35/hour... ...and disease mechanismsBasic computational skills and data analysis proficiencyPreferred...TargetWeekly payTemporary workWeekend work- ...About the role Preventive is seeking a computational biologist contractor to develop rigorous,... ...for these datasets. Safety and off-target profiling - Analyze WGS data from gene... ...-edited samples, including off-target discovery, validation, and analysis of SNVs/indels...TargetFull timeFor contractors
$198.9k - $369.3k
...marketed products. This Senior Principal (SE8) role is intended for... ...pathology strategy from discovery and candidate selection through... ...decisions. Anticipate potential target-, modality-, or mechanism-... ..., diagnostics, digital/computational pathology approaches, and new...PrincipalTargetLocal areaImmediate startRelocation package3 days per week$177k - $218k
...oncology company committed to the discovery, development, and... ...potentially first-in-class, targeted therapies aligned to the genetic... ...based design skills and modern computational tools to design targets with... ...range for the role of Principal Research Scientist, Medicinal...PrincipalTargetTemporary workWork at officeLocal areaWork from home1 day per week- ...Scientist or Senior Scientist to lead computational genomic analysis for low-input and single... ...considerations. Safety and off‑target profiling: Genome‑wide assessment of edited... ...of the following: End‑to‑end off‑target discovery/validation for gene‑edited samples in preclinical...Target
- ...South San Francisco seeks a Scientist to advance rare disease biology. You will contribute to discovery and translational studies, working across disease biology, computational science, and translational teams to generate mechanistic insights. The role emphasizes...Target
- Genentech is seeking a Scientist 3 within the CTG to advance target discovery through state-of-the-art genomics, functional readouts, and... ..., requiring collaboration across immunology, genomics, and computational biology. A strong publication and/or patent record is...TargetRelocation package
- ...****@*****.*** Research Associate - Scientist I, Discovery Biology The OpportunityPlan, execute, and analyze in vitro cell... ...in cancer oncology, including mechanistic studies and new target identificationPerform routine and specialized cell culture (...Target
- ...involves planning and executing inflammation discovery research by designing experimental studies, applying computational and AI-driven approaches to disease biology, and... ..., collaborating across functions to support target identification and therapeutic hypothesis refinement...Target
- Merck is seeking a Senior Scientist to join the Respiratory Biology Discovery group. The role focuses on target identification, validation, translational biology, and mechanism-of-action studies for chronic lung diseases, using primary airway/alveolar epithelial biology...Target
- IDEAYA Biosciences, Inc. seeks a discovery medicinal chemist to advance oncology programs with high productivity in the lab and strategic proposal of target molecules. You will work on cutting‑edge synthetic targets, collaborating across multidisciplinary teams to push...Target
- Amgen invites applications for a Senior Scientist, Target Discovery & Biology - Functional Genomics in South San Francisco. You will join the Target Discovery & Biology team to advance target discovery and validation across Amgen’s therapeutic areas using functional genomics...Target
- ...and Early Development seeks a Senior/Principal Machine Learning Scientist to develop... ...models for perturbation biology and target/drug discovery. You will design predictive algorithms... ...images and text, and collaborate with biologists, chemists, data scientists, and other...Target
- ...leader to develop the Foundational Data and Models strategy in Computational Neuroscience. You will advance data ecosystems, apply AI... ...genetics and single-cell atlases to inform neurodegenerative targets and biomarkers. The role requires onsite presence at least 3 days...PrincipalRelocation package3 days per week
$124k - $155k
...focused on leveraging AI to transform drug discovery and development. The company is leading... ...historically hard-to-drug molecular targets. It is also developing foundation... ...technical standards, and partnering with computational and engineering colleagues to scale data...TargetFlexible hours$147.8k - $274.4k
...Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’... ...collaborative Senior/Principal Machine Learning... ...perturbation experiments for target and drug discovery. This... ...teams including biologists, chemists, data scientists...PrincipalTargetFull timeLocal areaWorldwide
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