Senior Principal Computational Chemist - Drug Design Hybrid
IDEAYA Inc
IDEAYA Biosciences in South San Francisco seeks a Senior Principal Research Scientist in Computational Chemistry with a strong industry track record to advance small-molecule discovery programs. You will lead design efforts, run structure- and fragment-based modeling, and mentor teams to develop potent, selective drug candidates. The role requires independence, deep technical depth, and a collaborative mindset to drive decision-making across target identification, hit discovery, and lead #J-18808-Ljbffr IDEAYA Inc
$196k - $242k
...in small-molecule drug discovery, structural... ...an accomplished Senior Principal Research Scientist in Computational Chemistry with significant... ...computational chemist with a strong track... ...medicinal chemistry design and project... ...status. EOE/AA/Vets. Hybrid Working Policy At IDEAYA...PrincipalSeniorTemporary workWork at officeLocal areaWork from home1 day per week$177k - $235k
...and industry partners, its vibrant drug-development pipeline, together create... ...:We are seeking an innovative Senior Scientist / Principal Scientist to bridge the gap between... ...antibody discovery and cutting-edge computational design. In this role, you will serve as the...PrincipalSenior$144.9k - $269.1k
...us Roche.Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s... ...methods to study these pathways (Senior Scientist). Additionally, successful... ...equivalent experience after PhD (Principal Scientist). The ideal candidate...PrincipalSeniorFull timeLocal areaWorldwideRelocation package3 days per week$167.4k - $310.8k
...Roche.Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’... ...Discovery (AIDD) group (Prescient Design), we are revolutionizing drug discovery... ...ML) techniques. We are seeking a Senior or Principal Machine Learning Scientist to...PrincipalSeniorFull timeLocal areaWorldwideRelocation package- Alector, Inc. in South San Francisco is seeking a Senior Associate Scientist, Computational Biology to advance our understanding of neurodegenerative disease... ...imaging and multi-omics data, collaborate with R&D to design experiments and translate results into actionable...Senior
- ...Principal Computational Biologist Are you ready to own the strategy behind how Gordian turns large... ...disease, and move validated targets into drug development. We are running this... ...discussions that strengthen experimental design, and make time to connect over weekly team...PrincipalDay shift
- ...oncology company in South San Francisco, is seeking a Principal Research Scientist in Medicinal Chemistry to lead discovery... ...and deliver clinical candidates. You will drive design, synthesis, and optimization of drug-like molecules within cross-functional teams, contributing...Senior
$144.9k - $269.1k
...OpportunityWe are seeking an exceptional computational chemist to apply cutting-edge computational... ...validation and optimization.AI/ML for Drug Discovery: In collaboration with our internal... ...of induced proximity discovery or design projects.Deep knowledge of computational...PrincipalFull timeLocal areaRelocation package$143.2k - $266k
...organization at Genentech is responsible for the design and generation of new therapeutic... ...oligonucleotide experience to join our team as a Principal Scientist (Group Leader), and support our... ...synthesis of novel oligonucleotides for drug discovery programs. The successful...PrincipalFull timeLocal areaRelocation package- A leading design consultancy in South San Francisco is seeking a Principal Experience Designer to lead strategies in the Customer Experience Suite. This role involves... ...skills, and the ability to innovate in a hybrid work setting. A bachelor's degree is required, and...Principal
- ...Therapeutic Modalities and Technologies group in Protein Sciences is seeking a Principal Scientist (Group Leader) to lead the design and synthesis of novel oligonucleotide modalities for drug discovery. You will guide a multidisciplinary team, mentor scientists, and...Principal
- ...disease, and move validated targets into drug development. We are running this... ...discussions that strengthen experimental design, and make time to connect over weekly team... ...these disease areas. Your mission as a Computational Biologist at Gordian is to leverage our...SeniorAgency workDay shift
$160k - $195k
...A biotechnology company in South San Francisco seeks a qualified professional to design synthetic strategies and develop drug candidates. Candidates must have a PhD in Chemistry and at least 5 years of experience. The role involves collaboration within multidisciplinary...SeniorFull time- ...Role We are seeking a Principal/AD Medicinal Chemist to lead and advance small molecule drug discovery programs... ...enabling studies. This is a senior, hands-on scientific... ...can independently design and execute medicinal... ...the integration of computational and AI-driven approaches...PrincipalRemote workWork visaFlexible hours
- ...of Gordian’s discovery platform. As a Senior Computational Biologist, you’ll analyze and help evolve... ..., and move validated targets into drug development. (more info on our website,... ...discussions that strengthen experimental design, and make time to connect over weekly team...SeniorAgency workDay shift3 days per week
- IDEAYA Biosciences, Inc. seeks a discovery medicinal chemist to advance oncology programs with high productivity in the lab and strategic proposal of target molecules. You will work on cutting‑edge synthetic targets, collaborating across multidisciplinary teams to push...Senior
$173.1k - $321.5k
...more time with the people we love.The Senior Principal Scientist serves as the scientific leader... ...Development, CMC, Regulatory, and Computational Sciences to identify and prioritize the... ...of 7 years’ experience in the field of drug discovery or development with extensive...PrincipalSeniorFull timeLocal areaRelocation package$147.8k - $274.4k
...Advances in AI, data, and computational sciences are transforming drug discovery and... ...motivated and collaborative Senior/Principal Machine Learning Scientist... ....In this role, you will:Design and apply predictive machine... ...including biologists, chemists, data scientists, and other...PrincipalSeniorFull timeLocal areaWorldwide$141.5k - $262.9k
...therapeutics spanning from drug discovery through... ...responsibilities of this Senior Scientist position... ...technological gaps and designing innovative solutions to... ...Systems (CIS) and Computational Toxicology—to establish... ...CRO environments.Senior Principal Scientist: Ph.D. with...PrincipalSeniorFull timeLocal areaRelocation package- ...Atlassian uses to ship. We are hiring a Senior Principal Engineer for our AI Foundations team,... ...measure it, the context we feed it, and the compute it runs on.The reach of this work is... ...At Atlassian, we strive to design equitable, explainable, and competitive...PrincipalSeniorWork at officeLocal area
$177k - $218k
...in small-molecule drug discovery, structural... ...medicinal chemist. The successful candidate... ...productive rate Design high-confidence reaction... ...skills and modern computational tools to design... ...for the role of Principal Research Scientist... .... Our hybrid approach to work at...PrincipalTemporary workWork at officeLocal areaWork from home1 day per week$278.53k - $345.04k
...thrive on solving complex challenges and designing scalable, ground breaking solutions.... ...for Roblox.You have:You have 7+ (for principal) or 4+ (for senior) years of experience designing and... ...a plus.You have a BS, MS, or PhD in Computer Science or a related discipline or equivalent...PrincipalSeniorFull timeWork experience placementH1bWork at officeLocal areaVisa sponsorshipMonday to Friday- ...South San Francisco, CA, invites a Principal Scientist in Structural Biology... ..., X-ray crystallography and computational modeling to reveal protein dynamics... ...You will guide discovery teams, design constructs, and translate insights into drug discovery strategies. The role...Principal
$198.9k - $369.3k
...scientific leadership across drug development, from early... ...and marketed products. This Senior Principal (SE8) role is intended for an... ...and regulatory colleagues to design fit-for-purpose GLP and non-... ...biomarkers, diagnostics, digital/computational pathology approaches, and...PrincipalSeniorFull timeLocal areaImmediate startRelocation package3 days per week- Genentech, part of Roche, is seeking a Senior Scientist to advance AI-driven antibody design and developability assessment within gRED/pRED collaborations. You will translate computational predictions into actionable insights for portfolio projects and help scale models...Senior
$135k - $145k
...patients using advanced structure‐based and computational drug discovery technology. The company’s... ...chemistry, and data integration to design orally available, superior small molecule... ...report to a Sr. CTM or Associate Director. Hybrid SSF preferred with remote considered....SeniorContract workWork at officeRemote work$168.6k - $313k
...and experienced Medicinal Chemist (Senior Principal Scientist) to join our innovative... ...expertise to solve complex drug discovery challenges and... ...therapeutics. Govern the design and synthesis of innovative... ...conformational analysis, and computational methods to implement...PrincipalSeniorLocal areaRelocation package- ...Sciences in South San Francisco seeks a Principal Scientist in Structural Biology to drive drug discovery by integrating structural data, computational modeling, and biophysical insights. You will oversee protein construct design, expression, purification, and high‑resolution...Principal
- ...Research and Early Development seeks a Senior/Principal Machine Learning Scientist to... ...for perturbation biology and target/drug discovery. You will design predictive algorithms, integrate molecular... ..., and collaborate with biologists, chemists, data scientists, and other...Senior
- ...Senior Research Statistician providing statistical support for drug discovery and clinical development programs, with focus on biomarker analysis and precision medicine... ...discovery, translational, and clinical teams to design, analyze, and report multi-dimensional biomarker...Senior
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