Lead Computational Biologist: Target Discovery & MOA
Gordian Biotechnology
Gordian Biotechnology is seeking a Principal Computational Biologist to shape how large-scale in vivo perturbation screens are analyzed and translated into therapeutic targets. You will define methods for perturbation data, partner with disease experts for forward screen planning, and drive cross-team standardization in analytics. You should bring a Ph.D. in a quantitative field, 2+ years in industry, and deep experience in single-cell transcriptomics, ML, and data integration, with a track #J-18808-Ljbffr Gordian Biotechnology
- ...pipeline of therapeutic targets across chronic and... ...of Gordian's discovery efforts. In this... ...frameworks the rest of the computational team builds on.... ...Computational Biologist, you go beyond... ...person a disease lead relies on to make... ...deeper insights into MOA and target prioritization...TargetAgency workRemote workDay shift3 days per week
- ...transcriptomic data is at the heart of Gordian's discovery efforts, and the company will succeed... ...us to confidently prioritize the best targets and interventions. The Destination... ...disease areas. Your mission as a Computational Biologist at Gordian is to leverage our in vivo...TargetAgency workDay shift
- ...data is at the heart of Gordian’s discovery platform. As a Senior Computational Biologist, you’ll analyze and help evolve... ...perturbational data into robust targeted hypotheses. You’ll bring creativity... ...work directly with disease‑area leads, bringing Perturb‑seq or pooled perturbation...TargetAgency workDay shift3 days per week
- ...hiring a Scientist or Senior Scientist to lead computational genomic analysis for low-input and... ...specific considerations. Safety and off‑target profiling: Genome‑wide assessment of edited... ...the following: End‑to‑end off‑target discovery/validation for gene‑edited samples in...Target
$131.33k - $189.53k
...Freenome, we are seeking a Computational Biologist to help grow the Freenome Computational... ...role. What you’ll do: Lead the analysis and... ...methylation data for biomarker discovery research. Experience in developing... ...information: The US target range of our base salary rate...TargetLocal areaRemote work$188.28k - $270.38k
...are seeking a seasoned Staff Computational Biologist to help grow the Freenome... ...Staff Computational Biologist leading genomics modeling within... ...genome bisulfite sequencing, targeted sequencing, RNA sequencing,... ...techniques for biological discovery and product development,...TargetContract workFor contractorsFor subcontractorWork at officeLocal areaRemote work- Genentech is seeking a Scientist 3 within the CTG to advance target discovery through state-of-the-art genomics, functional readouts, and... ..., requiring collaboration across immunology, genomics, and computational biology. A strong publication and/or patent record is...TargetRelocation package
- ...Bioinformatics Engineer - Oligonucleotide Drug Discovery As molecular data generation and... ...part of a team of software engineers, biologists, and drug hunters building datasets to... ...to reason better across: Genetic target and MoA selection ASO/siRNA drug design Screening...TargetFull timeContract workWork at officeRemote workFlexible hoursNight shift
- Amgen is seeking a Scientist in Integrated Computational and Experimental Inflammation Discovery to advance inflammation programs through planning and coordinating... ...our understanding of disease biology and inform target discovery. You will manage program components with...Target
- insitro is seeking a computational biologist in South San Francisco to lead multimodal analyses and target discovery for drug development. You will work with life scientists, data scientists, and ML engineers to translate omics or imaging data into therapeutic hypotheses...Target3 days per week
- ...comSenior Research Associate - Scientist I, Discovery Biology The OpportunityPlan, execute, and... ..., including mechanistic studies and new target identificationPerform routine and... ...cell lines and/or primary cells) to support lead progression and follow-up studiesIndependently...Target
- ...while transforming your career. Scientist, Integrated Computational and Experimental Inflammation Discovery What You Will Do Let’s do this. Let’s change the... ...biology, refine therapeutic hypotheses and support target discovery. Working with minimal supervision, you will...TargetFlexible hours
- ...Scientist Experimental Protein Design for Target Discovery What You Will Do Lets do this. Lets change... ...world. In this vital role you will build and lead high-throughput platforms for binder generation, translating computational protein designs into experimentally validated...TargetFlexible hours
- Amgen is seeking a Senior Director of Small Molecule Drug Discovery in Inflammation to lead early discovery inflammation programs from target ID through preclinical assessment. You will shape strategy across modalities and manage matrixed teams, driving high-impact programs...Target
- IDEAYA Biosciences is seeking a discovery medicinal chemist to join our South San Francisco team. You will lead synthetic chemistry efforts, propose target molecules, and work in cross‑functional teams to advance oncology programs onsite five days a week. The role requires...Target
- Merck is seeking a Senior Scientist to join the Respiratory Biology Discovery group. The role focuses on target identification, validation, translational biology, and mechanism-of-action studies for chronic lung diseases, using primary airway/alveolar epithelial biology...Target
- ...based assays, including multiplex assays and digital image analysis, to support target expression studies, preclinical model development, pharmacodynamics, efficacy, and biomarker discovery. Responsibilities include developing and validating histopathology assays, using...Target
- Amgen invites applications for a Senior Scientist, Target Discovery & Biology - Functional Genomics in South San Francisco. You will join the Target Discovery & Biology team to advance target discovery and validation across Amgen’s therapeutic areas using functional genomics...Target
- Amgen in South San Francisco seeks an Associate Scientist Discovery Proteomics to expand LC-MS/MS-based workflows supporting the early discovery... ..., and bioinformatics teams to deliver high-quality data for target discovery and mechanism studies. The role emphasizes detailed...Target
$189k - $274k
...within the AIUX repertoire.Design targeted experiments around core... ...Bachelor's degree in Design, Human-Computer Interaction (HCI), Computer... ....4 years of experience leading design projects.3 years of experience... ...benefit and scientific discovery, ensuring safety and ethics are...Target- ...involves planning and executing inflammation discovery research by designing experimental studies, applying computational and AI-driven approaches to disease biology, and... ..., collaborating across functions to support target identification and therapeutic hypothesis refinement...Target
$210k - $250k
Lead, Oncology and Translational Medicine, is a key scientific... ...integral member of the drug discovery team accountable for all translational... ...-disciplinary team including computer scientists is required.... ...discovery research and new target ideation through the insights...Target$180k - $220k
...available AI Co-Scientist. It is a discovery engine that transforms messy... ...with analysis, novel targets, hypotheses, and patent-ready... ...growth ~ Trusted by leading biotechs and big pharma across... ...Strong experience in ML, computational biology, scientific computing...TargetWork at office- ...environment. Experience in one or more of the following areas: target identification & validation, adipose, liver, or muscle biology,... ...understand biology, mechanism of action and drive it through the discovery pipeline. Ability to work independently in executing tightly...TargetShift work
- ...of patients while transforming your career. Senior Scientist, Target Discovery & Biology - Functional Genomics What you will do Let’s do this... ...discover novel targets and address key biological questions Lead, support and execute projects from inception through target identification...TargetFlexible hours
- Amgen is seeking a Scientist for Integrated Computational and Experimental Inflammation Discovery in the United States. You will plan and coordinate tasks, generate... ...deepen understanding of disease biology and guide target discovery. Working with minimal supervision, you...Target
$163k - $203.8k
...Business Risk and Enablement team is hiring a Knowledge & Enablement Lead to own the frameworks and governance for how Mercury's risk... ...). It is a system design and framework role with real execution target behind it. You will set the requirements, standards, and review...TargetOdd jobFlexible hours$172.4k - $334.5k
...next-generation ideas. You will lead a team of engineers,... ...creator services, e.g., brand deal discovery, negotiation, storefront management... ...succeedBachelor's degree in computer science, engineering, or... ...salaries are expressed as total target compensation (TTC = base +...TargetFull timeTemporary workLocal areaWorldwide$152k - $221k
...Minimum qualifications:Bachelor's degree in Computer Science, Information Systems, Engineering... ...and/or product partners. You will lead cross-functional teams in Engineering, Sales... ...US: $152000 - $221000 (USD) + 15% bonus target + equity + benefitsLearn more about benefits...Target$153k - $210.1k
...frontier AI models, massive compute, and frontier experimental... ...system to accelerate scientific discovery, integrating frontier AI... ...seeking a Computational Biologist to help lead image analysis for our next... ...program. Bonus eligibility and targets are determined in...Work at officeRelocation package3 days per week
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