Postdoctoral Researcher Positions in Structural Biology / Biochemistry and Cell Biology
University of Cincinnati
Postdoctoral Researcher Positions in Structural Biology / Biochemistry and Cell Biology Posting Start Date: 8/24/26 Work Arrangement: Onsite Current UC employees must apply internally via SuccessFactors You are invited to apply to be considered for one of multiple vacancies of the same position. Next Lives at the University of Cincinnati Founded in 1819, the University of Cincinnati ranks among the nation's best urban public research universities. Home to more than 53,600 students, 12,000 faculty and staff, and over 360,000 living alumni, UC, a Carnegie 1 institution, combines research prowess with a physical setting The New York Times has called "the most ambitious campus design program in the country." UC's momentum has never been stronger as the anchor of the Cincinnati Innovation District, the oldest cooperative education (co-op) program in the country with students earning $94 million annually through paid experiences, an academic health system, and as a member of the Big 12 Conference. The university contributes $10.6 billion in economic impact to the city and $22.7 billion to the state of Ohio. At UC, next is all of us. Learn more at uc.edu. UC is a mission-driven organization where we are committed to student success and positively transforming the community through scholarship and service. We thrive on innovation, making an impact, and fostering an environment where staff and faculty are key contributors to UC's success. Job Overview Two postdoctoral researcher positions are available in the Joiner Lab at the University of Cincinnati ( We are seeking highly motivated candidates with expertise in either structural biology/biochemistry or cell/molecular biology to pursue independent and collaborative research addressing fundamental questions related to 1) the regulation of small GTPases in organelle homeostasis and neurodegenerative disease, and 2) the production of methane by anaerobic methanogens. Our laboratory integrates biochemical, structural, and cell-based approaches and we strive to maintain a highly collaborative research environment that values mentorship, intellectual exchange, and the professional development of all lab members. The lab is committed to mentoring postdoctoral researchers as they develop scientific independence and prepare for career paths . Postdocs will receive regular feedback, structured mentoring, and opportunities to build skills in experimental design, communication, and leadership. We expect active participation in collaborations, manuscript preparation, grant and fellowship applications, and the mentoring of junior trainees. These are full-time positions, each initially funded for 1-2 years, with the possibility of renewal contingent on performance and funding availability. Postdoctoral researchers will have access to state-of-the-art core facilities and institutional resources supporting professional development. This position is not eligible for H-1B sponsorship. Essential Functions Gather and analyze data and develop new ideas that promote current research. Prepare data summaries, reports, manuscripts and presentations of research results. Participate/assist in manuscript writing for publication in scientific journals and/or presentation; may assist in grant writing. Keep informed of developments in field to maintain and enhance professional expertise. Lab maintenance, including equipment maintenance and ordering of supplies, as needed. Teach techniques to others, train, and mentor junior research staff. This job description can be changed at any time. Minimum Requirements Position 1: Structural Biology / Biochemistry Research Focus This position will focus on illuminating the structural mechanics of these systems by using protein biochemistry, in vitro reconstitution, and structural biology approaches. Minimum Requirements
- PhD in Biochemistry, Structural Biology, Biophysics, or a related discipline
- Extensive experience in protein expression and purification
- Strong experimental design, data analysis, and problem-solving skills
- Experience with cryo-electron microscopy, including sample preparation and/or data processing pipelines
- Experience developing and performing in vitro biochemical or biophysical assays
- Familiarity with structure-function analysis of proteins or protein complexes
- PhD in Cell Biology, Molecular Biology, or a related discipline
- Strong experience with cell culture and cell-based assays
- Ability to independently design, execute, and interpret experiments
- Experience with gene editing approaches (e.g., CRISPR/Cas-based methods)
- Experience with fluorescence microscopy, including live-cell or quantitative imaging
- Familiarity with image analysis and data quantification workflows
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