R&D Solutions Architect, Senior Manager

Job Summary The Solutions Architect, Senior Manager defines and drives end‑to‑end solution architecture for cross‑functional R&D initiatives, with primary focus on clinical development, regulatory, and pharmacovigilance. You translate business needs into secure, scalable, and interoperable solution designs that enable study execution, evidence generation, submissions, and pharmacovigilance operations. Responsibilities Define and advocate target architecture, architecture vision, and ways of working for R&D solutions spanning clinical development, regulatory, and pharmacovigilance. Support solution evaluation and selection, including buy vs. build considerations, vendor/product fit assessments, and early‑phase sizing and estimation. Lead technical and solution design for assigned initiatives, from discovery through detailed design and delivery alignment. Produce high‑quality architecture artifacts such as target‑state and solution architecture, integration, and data flow designs, and support approval through enterprise and peer design reviews. Ensure solutions align with architecture standards and principles, leveraging common platforms, shared services, and reusable patterns. Provide architecture guidance to delivery teams and support organizations to help resolve design risks, technical debt, and alignment to IT and R&D strategies. Develop solution architecture grounded in R&D constraints, including regulated environments, validation needs, privacy, interoperability, and ecosystem dependencies. Architect information delivery, advanced analytics, and BI capabilities that enable R&D insights and reporting for clinical, regulatory, and safety outcomes. Stay current on emerging trends in clinical research and development, regulatory technology, pharmacovigilance, data, and AI/ML, and translate them into practical, compliant architecture recommendations. Ensure compliance with applicable privacy, security, and data protection requirements, and promote auditability and traceability by design. Qualifications Bachelor’s degree or equivalent experience (Master’s preferred). 5+ years in technology roles with progressive responsibility; experience in pharmaceutical/biotech or other regulated industries preferred. Track record of delivering technology and process change end‑to‑end, balancing speed, quality, and risk. Operates with high autonomy and sound judgment; able to lead through ambiguity and drive decisions without direct authority. Strong communication, facilitation, and mentoring skills; able to raise the technical bar across teams. Detail‑oriented and quality‑focused, with a bias toward pragmatic solutions that are secure, compliant, and supportable. Experience with regulatory compliance and data governance in a healthcare/pharmaceutical context (clinical, regulatory, and/or safety). Compensation & Benefits Location: Boston, MA, U.S. Base Salary Range: $137,000 – $215,270. U.S. based employees may be eligible for short‑term and/or long‑term incentives, medical, dental, vision insurance, a 401(k) plan with company match, short‑term and long‑term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well‑being benefits. Employees are eligible to receive up to 80 hours of sick time per calendar year and new hires accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. #J-18808-Ljbffr Takeda Pharmaceuticals International GmbH