Senior Medical Director, Clinical Development, Oncology (Remote)

Job Description

If you are a current Jazz employee please apply via the Internal Career site.

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Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit for more information.

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• Senior Medical Director, Solid Tumor Oncology
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• Position Summary
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• The Senior Medical Director, Solid Tumor Oncology , is a senior clinical leader responsible for shaping and executing the medical and clinical strategy for solid tumor programs across the drug development lifecycle. This role provides deep scientific and medical leadership, drives high‑quality evidence generation, partners cross‑functionally to advance pipeline assets, and represents the organization to external stakeholders, including regulatory agencies, investigators, and key opinion leaders.
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• The Senior Medical Director is accountable for ensuring robust clinical development plans, patient‑centric trial designs, and scientifically rigorous decision‑making aligned with the company’s oncology strategy.
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• Key Responsibilities
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• Clinical & Medical Leadership
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• Provide strategic medical oversight for solid tumor oncology programs from early development through registration and post‑approval.
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• Serve as the medical authority for assigned assets, ensuring scientific integrity, patient safety, and regulatory compliance.
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• Guide clinical trial design, endpoint selection, biomarker strategy, and translational integration.
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• Oversee medical monitoring and contribute to safety governance committees, including SMCs and DMCs as needed.
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• Development Strategy & Execution
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• Lead the development and execution of integrated clinical development plans aligned with unmet medical needs and competitive landscape.
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• Collaborate with Clinical Development, Regulatory Affairs, Biostatistics, Clinical Operations, and Translational Medicine to drive timely and high‑quality trial delivery.
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• Contribute to portfolio strategy, asset prioritization, and lifecycle management decisions.
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• Regulatory & External Engagement
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• Act as a key medical contributor in regulatory interactions with global health authorities (e.g., FDA, EMA).
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• Support preparation and review of regulatory documents, including protocols, CSRs, IBs, IND/CTA submissions, and briefing packages.
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• Build and maintain strong relationships with investigators, academic collaborators, and external experts.
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• Medical Affairs & Scientific Communication
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• Partner with Medical Affairs to ensure seamless transition from development to launch and post‑marketing activities.
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• Contribute to publication strategy, abstract development, congress presentations, and scientific exchange.
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• Serve as a credible scientific spokesperson for solid tumor programs, internally and externally.
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• Leadership & Talent Development
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• Provide mentorship and leadership to medical directors and physicians within the oncology organization.
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• Foster a culture of scientific excellence, collaboration, accountability, and patient focus.
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• Influence cross‑functional teams through thought leadership rather than authority alone.
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• Qualifications
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• Education & Training
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• MD or MD/PhD required; board certification in Oncology, Hematology‑Oncology, or a related specialty required.
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• Advanced clinical training and experience in solid tumor oncology required.
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• Experience
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• 10+ years of clinical and/or pharmaceutical industry experience in oncology, with significant solid tumor focus ( thoracic oncology experience preferred ).
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• Demonstrated leadership in global clinical development and late‑phase programs.
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• Proven experience with regulatory interactions and contribution to successful filings.
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• Track record of strategic leadership across complex, matrixed organizations.
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• Skills & Competencies
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• Strong strategic thinking combined with operational execution skills.
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• Excellent communication, influencing, and stakeholder‑management capabilities.
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• High ethical standards, sound medical judgment, and strong patient‑centric mindset.
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• Preferred Attributes
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• Experience leading registrational or practice‑changing Thoracic oncology studies .
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• Familiarity with biomarker‑driven development and precision oncology approaches.
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• Comfort operating in fast‑paced, evolving pipeline environments.
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Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law.

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FOR US BASED CANDIDATES ONLY

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Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is: $308,000.00 - $462,000.00

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Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis.

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At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz's Long Term Equity Incentive Plan.

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The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: