Research Scientist, Sr

Overview

GENERAL SUMMARY OF POSITION:

Under the general direction of the Principle Investigator, the Senior Research Scientist performs a variety of complex research experiments laboratory research on topics pertinent to the interests of the research programs of the laboratory. Work under limited supervision in carrying out complex research assignments, performance of experiments and recording of results: creation, amplification, maintenance and quality control of recombinant adenovirus and adeno-associated virus vector stocks, tissue histology, Western blots, qPCR, RT-PCR, PCR, work with recombinant DNA including mutagenesis and recording of experimental results, growth and maintenance of cell cultures, preparation of reagents for experiments, may also assist in procedures on experimental animals. Be proficient and independent in molecular methods and teach methods to technicians and trainees. Working with the P.I. and other lab members to interpret experiments. Utilize new and innovative research techniques, and adapting new assays for use in the lab, evaluate the adequacy of techniques and test new procedures. Perform lab management duties including ordering and maintaining supplies and equipment, maintaining records of grant expenditures and purchases, developing and implementing institution-required safety plans, other regulatory obligations of the laboratory and other necessary paperwork, and supervision of other lab technicians. Responsibilities

MAJOR RESPONSIBILITIES:

Design and implement experiments designed to further ongoing research projects, in consultation with the principal investigator. Organize and analyze data acquired in the course of research projects. Write manuscripts and grant applications. Design and implement research projects in the laboratory. Responsible for data acquisition, data analysis, and presentation of research results. Train and supervise junior lab personnel, ensuring staff is trained in current methodology and safety procedures in the laboratory. Prepare and present data for publication in public forums. Assist in the preparation of grant applications and other research proposals. Provide assistance in the general operation of the laboratory. Participate regularly in laboratory meetings. Stay current with the literature and regularly lead discussions of new reports pertinent to ongoing and proposed projects. Perform other duties as required. Qualifications

REQUIRED QUALIFICATIONS:

Bachelor’s degree in a Biological Science, or equivalent degree. 7 years of research experience. Familiarity with general laboratory procedures. Expertise in specific procedures and instrumentation necessary to complete specific research programs. Current knowledge of pertinent literature. Oral and written communication and presentation skills. Ability to travel to off-site locations.

SUPERVISION RECEIVED:

Under the general direction of the Principle Investigator.

SUPERVISION EXERCISED:

Supervises and trains new laboratory personnel and junior members of the laboratory.

ENVIRONMENTAL WORKING CONDITIONS:

Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens. #J-18808-Ljbffr University of Massachusetts Medical School