Principal System Administrator

Principal System AdministratorHistoSonics is a commercial-stage medtech company advancing the Edison® System, a novel non-invasive sonic beam therapy based on histotripsy. Since receiving FDA De Novo grant for the non-invasive destruction of liver tumors in 2023, the company has progressed beyond initial market entry into commercial expansion, reimbursement momentum, and ongoing clinical and pipeline development. In addition to its current liver tumor indication, HistoSonics is pursuing future indications across multiple applications including kidney, pancreas, prostate, neuro, women's health, and other significant underserved human health areas, to realize the broader potential histotripsy across multiple disease states and medical specialties.Location: Plymouth, MNPosition Summary (Why this role matters):The Principal System Administrator is the senior-most individual contributor within the HistoSonics System Administration function and is a member of a larger, multi-site IT team that supports HistoSonics as a whole. This is a hybrid position based out of the Plymouth, MN office. The role owns the design, operation, and reliability of the organization's cloud and on-premises infrastructure, enterprise identity and authentication services, backup and disaster recovery, and environments that support deployed systems in the field. The Principal System Administrator establishes the organization's observability practice and provides the primary technical execution behind the Information Systems relationship with the AI and R&D Infrastructure team within the CTO organization, a partnership owned by the Senior Director, Information Systems and Security. The role serves as the highest level of technical escalation for Information Systems infrastructure and sets technical direction and standards for the System Administration function.Key Responsibilities (What you'll do):Infrastructure and Cloud OperationsObservability and ReliabilityAutomation, Governance, and StandardsSecurity, Compliance, and ResilienceTechnical Leadership and CollaborationQualifications and Skills:Required:Bachelor's degree in Information Technology, Computer Science, or a related field, or equivalent experience10+ years of progressive experience in system administration, infrastructure engineering, or site reliability engineering, including experience above senior level.Expert-level administration experience with at least one major public cloud platform (AWS or Azure) and intermediate to advanced experience with another, including tenant-level governance such as resource hierarchy, subscription or account structure, management groups, policy-as-code, and landing zone design.Demonstrated experience operating customer-facing or product production environments that are mission critical, including service level objectives, change control, incident response, and root cause analysis.Intermediate to expert experience designing and administering observability platforms covering metrics, logs, traces, and alerting; experience with Prometheus, Grafana, OpenTelemetry, or comparable dynamic, service-discovery-based tooling is preferred.Demonstrated DevOps/SRE experience, including infrastructure-as-code (Terraform, CloudFormation, or similar), CI/CD pipeline construction, and configuration management, with advanced scripting ability in PowerShell, Python, and Bash.Experience defining infrastructure standards and reusable modules adopted and applied by teams across an organization.Advanced administration experience with Windows Server and at least one major Linux distribution, and with enterprise identity including Microsoft 365, Entra ID, SAML federation, conditional access, IGA tooling, and certificate-based authentication.Experience designing, administering, and testing enterprise backup and disaster recovery solutions; working knowledge of hybrid and cloud networking; and experience making changes within an environment compliant with ISO 27001 and SOC 2 standards.Preferred:Experience in a regulated industry such as medicaldevice, healthcare, or manufacturing.Experience with containerization and orchestration (Docker, Kubernetes, EKS, AKS), virtualization platforms (VMware vSphere, Hyper-V), incident escalation tooling such as PagerDuty.Experience with implementing workflows executed by AI agents for productivity purposes.Relevant industry certifications are a plus.Key Competencies:Strong problem-solving and troubleshooting skills, with sound judgment and composure when responding to incidents affecting production or product-facing systems, and a bias toward automation, standardization, and durable documentation.Excellent communication and interpersonal skills, with the ability to explain infrastructure decisions, risks, and trade-offs to technical and non-technical audiences, and to prioritize tasks and manage time effectively while working independently and as part of a team.Ability to set technical direction and influence outcomes across teams and departments without direct reporting authority.Physical Requirements:Reasonable accommodation may be made to enable individuals with disabilities to perform the essential functions.Ability to occasionally lift or move equipment weighing up to 50 pounds, with or without reasonable accommodation.Ability to work in server rooms, data closets, and other equipment areas, including bending, kneeling, and reaching to install and service equipment.Benefits: We offer a comprehensive benefits package for full-time employees. This includes health, dental, and vision insurance, life, short-term and long-term disability insurance, 401(k), paid time off, and more.We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.U.S. Work Authorization & Sponsorship: Employer will not sponsor visas for position.#LI-hybrid