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Principal Scientist, Translational Science Program Lead, Immunology

Johnson & Johnson

Principal Scientist leading translational science strategy for immunology programs from discovery through clinical development. This role owns end-to-end translational planning, biomarker strategy, and cross-functional execution for assigned therapeutic assets at Johnson & Johnson.

Responsibilities

  • Develop and maintain integrated translational plans connecting disease biology, mechanism, biomarkers, and clinical endpoints
  • Lead precision medicine strategy including patient stratification, biomarker endpoints, and target product profile development
  • Anticipate program inflection points and define critical evidence requirements, decision criteria, and risk mitigation
  • Represent translational science across discovery and clinical teams, aligning partners around integrated recommendations
  • Interpret preclinical and clinical data to generate actionable insights and communicate findings to governance bodies

Requirements

  • Deep expertise in immunology and translational medicine
  • Proven ability to develop integrated translational strategies and stage-appropriate evidence plans
  • Strong proficiency analyzing multidimensional biomarker data and high-dimensional datasets
  • Experience leading in matrixed environments and influencing cross-functional teams
  • Track record translating disease biology and therapeutic mechanisms into clinical development decisions
  • Demonstrated scientific credibility and external collaboration experience
Vacancy posted 1 day ago
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