Senior Project Manager
$108.5k - $201.5kProduction / Manufacturing
Summary
What does it take to lead some of the most significant capital investments in pharmaceutical manufacturing? As a Senior Project Manager at Novartis, you will provide end-to-end leadership for large-scale GMP capital programs that support the growth and future of our Durham campus. This role is designed for an experienced project leader with a proven track record of successfully delivering multiple capital projects valued at approximately $400 million or more, from initial concept through operational handover. Working across Engineering, Construction, Manufacturing, Quality, Automation, EHS, and external partner organizations, you will drive complex facility expansions and strategic investments that strengthen our ability to deliver high-quality medicines to patients worldwide.
About the Role
Location:
- This position will be located in Durham, NC and will be an onsite role.
- Novartis is unable to offer relocation support for this role: please only apply if this location is accessible for you.
Key Responsibilities:
- Lead large-scale GMP capital projects supporting sterile manufacturing, packaging, and facility expansion initiatives.
- Direct projects from business case development through design, procurement, construction, CQV, turnover, and closeout.
- Serve as the primary engineering and project leadership representative for major capital investment programs.
- Partner across Engineering, Manufacturing, Quality, Automation, Procurement, EHS, and external contractor organizations.
- Develop and manage project scope, budget, schedule, governance, KPIs, and execution strategies.
- Drive proactive risk management, mitigation planning, and resolution of complex project challenges.
- Oversee A/E firms, construction partners, OEMs, vendors, and contractors to ensure successful project delivery.
- Ensure compliance with GMP requirements, site standards, quality expectations, and EHS requirements.
- Communicate project performance, financial status, risks, and key milestones to senior leadership.
- Mentor project teams and promote operational excellence through standardized capital project delivery practices.
Essential Requirements:
- Bachelor’s degree in Engineering, Construction Management, Project Management, or a related technical discipline.
- 9+ years leading large-scale capital projects within pharmaceutical, biotechnology, or other GMP-regulated manufacturing environments.
- Proven success managing multiple capital projects valued at approximately $400M+ from initiation through completion.
- Experience delivering complex projects across design, procurement, construction, CQV, operational readiness, turnover, and closeout.
- Strong knowledge of GMP, cGMP, FDA, validation, and regulatory requirements within regulated manufacturing facilities.
- Experience leading capital programs involving facilities, utilities, process equipment, automation, and cleanroom environments.
- Demonstrated ability to manage budgets, schedules, risks, change controls, and executive stakeholder communications.
- Exceptional leadership, influencing, and cross-functional collaboration skills within complex matrix organizations.
Novartis Compensation and Benefit Summary:
The salary for this position is expected to range between $108,500 and $201,500 Annually.
The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.
Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.
US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.
#LI-Onsite
Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together?
Benefits and Rewards: Learn about all the ways we’ll help you thrive personally and professionally.
Read our handbook (PDF 30 MB)
EEO Statement:
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility & Reasonable Accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call View phone number on us.fitly.work and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
$78.7k - $196.8k
Senior Project Manager, Linguistic Validation & eCOAOverviewIQVIA is currently looking to expand our Translations Services team in the United States due to continued growth and demand for Linguistic Validation & eCOA services. We are currently seeking a Senior Project...SeniorFull timePart timeImmediate startWorldwide$108.5k - $201.5k
...Description SummaryWhat does it take to lead some of the most significant capital investments in pharmaceutical manufacturing? As a Senior Project Manager at Novartis, you will provide end-to-end leadership for large-scale GMP capital programs that support the growth and future...SeniorFull timeFor contractorsWorldwideRelocation package- ...Job Description Job Description Summary: Senior Project Scheduler is a leader and contributor in the organization within the scheduling function on multiple utility-scale solar and BESS projects ranging from $25MM to $300MM. This role requires full lifecycle project...SeniorWork experience placement
- The Sr Project Manager is expected to hit the ground running and must have the following:Experience with Data Warehouse environmentsExperience... ...onshore/offshore teamsHas extensive interaction with senior leadership Works with Business and Technical resource managers...Senior
- ...Job Description Job Description Are you an experienced Project Manager with a passion for bringing innovative medical and drug delivery... ...to life? At Gilero’s Durham's office, we’re looking for a Senior Project Manager to lead design and development projects in cutting...SeniorContract workTemporary workWork at office
- Sr. Project Manager - Permanent - Durham, USReady to lead transformative GMP capital projects that will shape the future of sterile manufacturing... ...and pharmaceutical innovation?Proclinical is seeking a Senior Project Manager to lead large-scale GMP capital projects...SeniorPermanent employmentFor contractors
- ...to improve health and improve lives.Labcorp is seeking a Senior IT Delivery Manager to join our team at Durham, NC office.Work ScheduleThis is... ...scope, schedule, cost, and quality targets are met.Develop project plans including scope definition, detailed activities, schedule...SeniorFull timeTemporary workCasual workInternshipWork at officeMonday to FridayFlexible hoursDay shift3 days per week
$163.1k
Role OverviewThe Solution Delivery Lead (SDL) Senior Director will serve as a strategic and scientific leader for Real World Evidence... ...of RWE account teams responsible for sales, solutioning, and project management across the RWE book of work with global and regional...SeniorFull timePart timeImmediate startWorldwide$107.9k - $172.64k
...The Senior Technical Project/Program Manager leads complex, technology-driven projects and initiatives from planning through delivery, release, and post-implementation transition. This role is responsible for and equally accountable for the successful completion of one...SeniorFull timeWork at officeLocal areaRemote workFlexible hours2 days per week- ...activities for the system implementation project Partner with internal business... ...user training sessions and support change management activities Provide regular project status... ...Proven experience of around 3–5 years as a Senior Business Analyst, Project Manager, or...SeniorFull timeContract workTemporary workWork at officeImmediate start
$140k - $160k
...Role This is a dual-capacity position: you will provide both project management leadership and business analysisexpertiseto support large-scale... ....This isnot two half-roles stitched together.It’sa senior-level position for a seasoned professional who can seamlessly...SeniorTemporary workImmediate startRemote workShift work- ...Job Description Job Description SummaryThe Senior Project Manager is responsible for all project administration including all contractual requirements, agreements with trade partners, purchase orders, and risk management. This individual also manages general work...SeniorContract workApprenticeshipFor subcontractorLocal areaImmediate start
$105k - $115k
...Job Description Job Description Senior Project Manager Location: Chapel Hill, NC (Onsite; relocating to Timberlake, NC in Q4 2026) Schedule: Full-Time | Exempt Compensation: $105,000 - $115,000 annually Position Overview We are seeking a seasoned...SeniorFull timeLocal areaRelocation- ...Survey Project Manager ESP Associates, Inc. (ESP) is seeking a Survey Project Manager for oversight of surveying projects to support the corporate office in Morrisville, NC. This is an excellent opportunity for a survey professional to continue to grow your career in...SeniorTemporary workWork at officeFlexible hours
- ...Job Description Job Description POSITION: Sr. EPC Project Manager WHO WE ARE: Heelstone Renewable Energy is a utility-scale solar, wind, and storage developer headquartered in Durham, NC, with expertise in developing, originating, financing, constructing...SeniorFull timeTemporary workFor contractorsImmediate startWork from homeFlexible hours
- ...Job Description Job Description The Senior Director of Project Architecture is our senior design authority for utility-scale solar and storage... ...and storage developments, to construction, O&M, and Asset Management. Our employees are empowered to drive our business in a...Senior
- ...Job Description Job Description Senior Estimator / Project Manager Position Summary This is an exciting time to join our team. With a focus on safety, continued growth, profitability, and investment in our future, we are seeking an experienced Estimator /...SeniorFull timeContract workFor contractorsFor subcontractorWork at officeLocal areaFlexible hoursNight shiftAfternoon shift
- ...Come build something with Shepley Bulfinch as a Senior Healthcare Project Manager! Shepley Bulfinch is seeking a well-rounded Senior Healthcare Project Manager who is creative and passionate about architecture, curious about solving complex problems, and looking to...SeniorFull timeFor contractorsFlexible hours
$40 - $45 per hour
DescriptionJob DescriptionWe are seeking a highly organized and technically proficient Project Manager to lead and coordinate projects involving structured cabling, audio/visual systems, and security infrastructure (including access control and surveillance) within the...Contract workTemporary workFor subcontractor- ...and help transform the future of healthcare, you’ll find your purpose here.Job DescriptionPrimary Function of Position The Project Manager / Senior Project Manager, Advanced Tissue Models will be responsible for a diverse set of products and activities for the Advanced...Local areaWorldwideFlexible hours
- At Perkins&Will, we are seeking a Project Manager with 8-10 years of experience to join our Healthcare practice. As a Project Manager - Healthcare on the Perkins&Will team, your skills and passion will come to life through the following responsibilities: managing project...Full timeContract workFor contractorsWork at office
- ...stability, innovation, and growth are more than just values—they are the pillars of our continued success.OverviewThe Senior Service Project Manager is responsible for overseeing Service Project Managers and all aspects of the project and be responsible for managing the...SeniorContract workFor contractorsFor subcontractorWork at officeLocal area
$88.1k - $220.2k
Ready to make an impact in clinical research? Join IQVIA as an eCOA Implementation Project Manager and help shape patient-centric trials for leading global sponsors. In this client-facing role, you’ll manage complex startup projects, collaborate with cross-functional teams...Full timePart timeImmediate startWorldwide- ...What You'll Do We are seeking a highly motivated Sr. Manager, Business Operations, to support our GTM Organization. This individual will... ...also have a total of 8 employee‑run resource groups, each with senior leadership and exec sponsorship. We’re An Equal Opportunity...Senior
- Abinitio Developer with Healthcare Domain knowledge and BCBSNC experience - Internal US transfer of SIVA PRASAD VISWANADHA (Portal id 101275)Posting Date:Department:Delivery - Multi Niche Skills - 1003210015Senior
- ...Project Manager Onsite | Durham, NC | Full-Time Position Summary – The Project Manager plays a critical role in leading and executing... ...will be working closely with): Technical Teams Senior/Executive Management Business Development Finance Travel...Full time
- We are seeking a Project Manager to lead the development and implementation of Wolfspeed's advanced packaging initiatives across high-performance computing (HPC), AI data center, and AR/VR applications. In this role, you will manage the full project lifecycle — from initiation...Full time
- ...Job Description Job Description The Project Manager (PM) serves as the principal contractor representative responsible for the overall management, supervision, and coordination of all tasks, activities, and issues relating to the EPA Facilities Operations, Maintenance...Contract workFor contractorsFor subcontractorWork at officeImmediate startMonday to Friday
$97.5k - $130k
...Job Description Description: As a regional construction management company, we don’t just build buildings; we also build communities... ...learning and mentoring through a diverse portfolio of challenging projects, including adaptive reuse, historic preservation, renovations,...Contract workFor subcontractorWork at officeLocal area- The Project /Program Manager is responsible for the coordination and completion of projects within budget, scope, and schedule requirements. Project will vary across multiple areas of the Manufacturing BU, including new product development, product upgrades, quality improvements...Full timeWork experience placementWork at officeVisa sponsorshipWork visa
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Project Manager. Be the first to apply!
- senior lead project manager Durham, NC
- sr project manager Durham, NC
- community development project manager Durham, NC
- power generation project manager Durham, NC
- office furniture project manager Durham, NC
- change management project manager Durham, NC
- civil project manager Durham, NC
- remote senior project manager Durham, NC
- automation project manager Durham, NC
- project manager life sciences Durham, NC



