Scientific Associate Director - Safety Pharmacology
Amgen Inc
Amgen seeks a Scientific Associate Director to lead safety pharmacology laboratory operations and serve as a subject matter expert for nonclinical safety evaluation. The role combines lab management, project team collaboration, and external scientific engagement to support drug candidate development across multiple therapeutic modalities.
Responsibilities
- Oversee cardiac safety and electrophysiology laboratory operations including ion channel, hiPSC-derived cardiomyocyte, and isolated heart assays
- Supervise scientific staff, promote their development, and ensure high-quality timely data generation and reporting
- Serve as Safety Pharmacology Subject Matter Expert on translational safety teams supporting discovery and development programs
- Guide study design, data interpretation, and safety risk evaluation for small molecules, biologics, and emerging therapeutic modalities
- Build external collaborations and develop scientific eminence through publications, presentations, and promotion of human-relevant in vitro safety models
Requirements
- Doctorate degree with 4+ years relevant scientific experience, or Master's with 7+ years, or Bachelor's with 9+ years
- PhD in Pharmacology, Neuroscience, Physiology, Biomedical Sciences, or related field preferred
- Broad experience in in vitro and/or in vivo safety pharmacology across cardiovascular, respiratory, and CNS domains
- Working knowledge of cardiac ion channel assays and hiPSC-derived cardiomyocyte and isolated heart assays
- Demonstrated people leadership and laboratory management experience
- Experience managing outsourced studies, CRO relationships, and GLP-compliant safety pharmacology packages
- Strong cross-functional communication, problem-solving skills, and track record of scientific publications
Vacancy posted 6 days ago
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