Scientist, Rare Disease Biology

Amgen seeks a scientist to join its rare disease research team and contribute to discovery and advancement of innovative therapies. The role involves designing experiments, investigating disease mechanisms using cellular models, and collaborating across multidisciplinary teams to inform portfolio decisions.

Responsibilities

• Design, execute, and analyze in vitro and ex vivo studies investigating disease mechanisms and therapeutic hypotheses
• Generate high-quality experimental data supporting target identification and validation for rare disease programs
• Establish scalable experimental platforms supporting multiple rare disease research initiatives
• Integrate experimental findings with genetics, clinical observations, and literature to inform mechanistic insights
• Collaborate with disease biologists, computational scientists, and translational researchers; present findings to governance forums

Requirements

• PhD in Immunology, Neurology, Cell Biology, Molecular Biology, Pharmacology, or related field
• Master's degree with 3+ years scientific research experience, or Bachelor's with 5+ years experience
• Experience in neurobiology, genetic disease biology, or related therapeutic areas
• Expertise developing and utilizing iPSC-derived cellular models and advanced human cellular systems
• Familiarity with protein aggregation, RNA toxicity, cellular stress responses, or neurological disease mechanisms
• Experience in highly collaborative, matrixed research environments with scientific rigor and adaptability