Senior Scientist, Targeted Protein Degradation
Amgen Inc. (IR)
Amgen Inc. in Thousand Oaks, CA seeks a Senior Scientist to advance E3 ligase biology and molecular glue screening, translating hits into targets with therapeutic potential. You will design assays, validate hits, and collaborate across IPP teams to explore disease-relevant targets in oncology and related fields. The role requires strong biochemistry and molecular biology expertise, experience with high-throughput screening and mass spectrometry, and a track record of contributing to publications #J-18808-Ljbffr Amgen Inc. (IR)
$127.12k - $171.99k
...transform the lives of patients while transforming your career.Senior Scientist - Targeted Protein DegradationWhat you will doLet’s do this. Let’s change... ...disease areas.Within IPP, the Targeted Protein Degradation function integrates E3 ligase biology, chemical biology...SeniorFull timeFlexible hours- Amgen is seeking a Senior Scientist to advance targeted protein degradation through molecular glue screening, leveraging IPP to identify novel degradation targets. You will validate hits, characterize mechanisms, and translate findings into new therapeutic opportunities...Senior
$140.12k - $189.58k
...of the Amgen team. Join us and transform the lives of patients while transforming your career.Principal Scientist - Lead Discovery and Targeted Protein Degradation BiochemistryWhat you will doLet’s do this. Let’s change the world. In this role, you will lead protein reagent...SuggestedFull timeFlexible hours- Amgen in Thousand Oaks, CA is seeking a Process Development Senior Scientist to lead analytical and biochemical characterization for pre-clinical biotherapeutic protein development, including mass spectrometry and LC-MS workflows. You will develop methods to assess biochemical...Senior
$134.14k - $181.48k
...transform the lives of patients while transforming your career.Senior Scientist - Protein BiochemistWhat you will doLet’s do this. Let’s change the... ...reagents that support the structure determination of target molecules via X-ray crystallography and/or cryo-electron microscopy...SeniorFull timeFlexible hours$123.78k - $167.46k
...you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senoir Scientist, Protein Therapeutics - Mammalian Expression & Cell Line Engineering What you will do Let’s do this. Let’s change the world. In this vital...SeniorFlexible hours- Amgen in Thousand Oaks is seeking a Senior Scientist - Protein Biochemist to design and execute strategies for producing high-quality reagents for structural biology, including X-ray crystallography and cryo-EM. You will collaborate with structural biologists, optimize...Senior
- Amgen in Thousand Oaks seeks a Senior Scientist in Protein Biochemistry to drive design, expression, and purification of proteins for structural biology projects (X-ray, cryo-EM). You will collaborate with structural biologists to deliver high-quality samples for structural...SeniorFlexible hours
$127.12k - $171.99k
...Amgen team. Join us and transform the lives of patients while transforming your career.Senior Scientist - Functional GenomicsWhat you will doThe Functional Genomics group within Target Discovery and Biology (TD&B) is seeking a highly motivated Senior Scientist to develop...SeniorFull timeFlexible hours$127.12k - $171.99k
...the world. We are seeking a motivated Senior Scientist in mass spectrometry-based proteomics... ...deliver critical insights to support target identification and drug discovery,... ...reproducible results. Knowledge of targeted protein degradation or E3 ligase biology is a plus What...SeniorFull timeFlexible hours- Amgen in Thousand Oaks, CA is seeking a Senior Scientist in Functional Genomics to drive genome engineering for target discovery and validation. You will design and apply viral vector technologies (AAV, lentiviral) in multidisciplinary discovery teams, translating complex...Senior
- Amgen is seeking a Senior Scientist in Cardiometabolic Disorders to drive biology research, identify therapeutic targets, and guide drug discovery programs. The role combines bench science with leadership, focusing on osteoporosis and metabolic disease, with opportunities...Senior
- Amgen is seeking a Senior Scientist in Thousand Oaks, CA, to lead high-throughput mass spectrometry-based proteomics efforts. You will contribute to target identification, drug discovery and platform technology development, working with cross-functional teams to accelerate...Senior
- ...Amgen, based in Thousand Oaks, seeks a Principal Scientist to lead early validation efforts for membrane protein targets. You will guide cell-based and quantitative assays, partner with cross-functional teams, and drive robust, scalable workflows across discovery programs...
$127.12k - $171.99k
...Biology, In vitro Molecular Engineering & NGSThousand Oaks, CALet’s do this. Let’s change the world.Amgen Protein Therapeutics is seeking a highly motivated Scientist to join our multidisciplinary team in Thousand Oaks, CA. Our group integrates protein engineering and...SeniorFull timeFlexible hours$126.35k - $170.95k
...transform the lives of patients while transforming your career. Senior Scientist What You Will Do Let’s do this. Let’s change the world. Amgen... ...in collaboration with cross-functional partners, including protein therapeutics, medicinal chemistry, pharmacokinetics,...SeniorFlexible hours- ...CACompany: Planet Pharma GroupContact: ApplicationsEmail: ****@*****.*** PR Range: 19-26/hr DOEAssociate Scientist - Protein ChemistrySeeking a highly motivated Associate Scientist to join the Protein Therapeutics (PT) - Protein Chemistry team. PT is...
- Amgen Inc. is seeking a Process Development Senior Scientist to define quality attributes and advance analytical methods for protein therapeutics. You will develop LC-MS/MS based workflows, characterize modifications such as glycosylation and oxidation, and optimize chromatography...Senior
$165.5k - $223.91k
...transforming your career.Sr. Principal Scientist - Immunogenicity Bioanalytical SciencesWhat... ...ADAs & NAbs) for Amgen’s large molecule/protein therapeutics to support GLP preclinical... ...and clinical programs.Serve as a senior subject-matter expert for ADA, NAb, drug...SeniorFull timeFlexible hours$157.74k - $213.41k
...as part of the Amgen team. Join us and transform the lives of patients while transforming your career.Process Development Senior Principal Scientist BioconjugatesWhat you will doLet’s do this. Let’s change the world. In this vital role you will Amgen’s DSTS group within...SeniorFull timeFlexible hours$168.39k - $227.83k
...lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.Senior Principal ScientistWhat you will doLet’s do this. Let’s change the world! We are seeking an experienced toxicologist in the Product...SeniorFull timeWork at officeRemote workFlexible hours- Amgen is seeking a Process Development Senior Principal Scientist in Thousand Oaks, CA. You will lead formulation and process development for biologics, oversee tech transfer, and guide cross-functional teams to deliver scalable, stable drug products. The role emphasizes...Senior
- Amgen is seeking a Process Development Senior Principal Scientist in Thousand Oaks, CA to lead drug product design, formulation, and process development for biologics and ADCs. You will guide diverse teams through scale‑up, characterization, and regulatory readiness to...Senior
- Reference: 630597Posted: 2026-09-02Location: Thousand Oaks, CACompany: Planet Pharma GroupContact: ApplicationsEmail: ****@*****.*** PR Range: 35-45/hrJob Details: With minimal supervision, plans, conducts or monitors experiments, records and organizes...SeniorRelocation
- ...CACompany: Planet Pharma GroupContact: ApplicationsEmail: ****@*****.*** PR Range: 22-32/hr DOEAnalytical Scientist Senior Associate - Scope of duties includes small molecule analytical method development, routine testing, maintenance of...Senior
$127.12k - $171.99k
...transform the lives of patients while transforming your career.Senior Scientist - Cardiometabolic DisordersWhat you will doLet’s do this. Let... ...to conduct biology research and identify therapeutic targets in cardiometabolic disease that are tractable and offer the opportunity...SeniorFull timeFlexible hours$129.23k - $174.84k
...transform the lives of patients while transforming your career.Senior Scientist - Translational Safety & Risk Sciences (TSRS)What you will... ...toxicology, and/or translational safety approaches Understanding of target discovery, translational biology, nonclinical safety, drug...SeniorFull timeRemote workFlexible hours$126.07k - $170.56k
...within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.Senior Scientist (Small Molecule, Synthetics)What you will doLet’s do this. Let’s change the world. In this vital role you will serve as part...SeniorFull timeContract workFlexible hours- Amgen in Thousand Oaks seeks a Senior Scientist in Protein Biochemistry to lead design, planning, and execution of reagents for structure determination by X-ray crystallography and cryo-EM. You will collaborate with structural biologists to advance drug discovery and apply...
- Amgen in Thousand Oaks, CA seeks a Process Development Senior Scientist to advance oral solid dosage forms, including PROTACs and beyond‑Ro5 compounds. You will design robust formulations, partner with CMOs, and drive NDA‑readiness through IND/CMC work. The role offers...Senior
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