Senior Scientist, Targeted Protein Degradation
Amgen Inc. (IR)
Amgen Inc. in Thousand Oaks, CA seeks a Senior Scientist to advance E3 ligase biology and molecular glue screening, translating hits into targets with therapeutic potential. You will design assays, validate hits, and collaborate across IPP teams to explore disease-relevant targets in oncology and related fields. The role requires strong biochemistry and molecular biology expertise, experience with high-throughput screening and mass spectrometry, and a track record of contributing to publications #J-18808-Ljbffr Amgen Inc. (IR)
$127.12k - $171.99k
...transform the lives of patients while transforming your career.Senior Scientist - Targeted Protein DegradationWhat you will doLet’s do this. Let’s change... ...disease areas.Within IPP, the Targeted Protein Degradation function integrates E3 ligase biology, chemical biology...SeniorFull timeFlexible hours$140.12k - $189.58k
...of the Amgen team. Join us and transform the lives of patients while transforming your career.Principal Scientist - Lead Discovery and Targeted Protein Degradation BiochemistryWhat you will doLet’s do this. Let’s change the world. In this role, you will lead protein reagent...SuggestedFull timeFlexible hours- Amgen seeks a Senior Scientist to advance E3 ligase biology and molecular glue discoveries within the IPP program in Thousand Oaks, CA. You... ...drive screening and validation of degraders, identify novel targets, and translate findings into therapeutic opportunities. You will...Senior
- ...This principal scientist role leads protein reagent generation and biochemical assay development for drug discovery campaigns, with emphasis on targeted protein degradation programs. The successful candidate will oversee a small team, design protein production and characterization...Suggested
$134.14k - $181.48k
...transform the lives of patients while transforming your career.Senior Scientist - Protein BiochemistWhat you will doLet’s do this. Let’s change the... ...reagents that support the structure determination of target molecules via X-ray crystallography and/or cryo-electron microscopy...SeniorFull timeFlexible hours- Amgen in Thousand Oaks, CA is seeking a Process Development Senior Scientist to lead analytical and biochemical characterization for pre-clinical biotherapeutic protein development, including mass spectrometry and LC-MS workflows. You will develop methods to assess biochemical...Senior
- Amgen is seeking a Principal Scientist to lead initiatives in Lead Discovery and Targeted Protein Degradation Biochemistry in Thousand Oaks, California. You will take charge of protein reagent generation and biochemical assay development aimed at advancing drug discovery...
$127.12k - $171.99k
...Amgen team. Join us and transform the lives of patients while transforming your career.Senior Scientist - Functional GenomicsWhat you will doThe Functional Genomics group within Target Discovery and Biology (TD&B) is seeking a highly motivated Senior Scientist to develop...SeniorFull timeFlexible hours$127.12k - $171.99k
...ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.Senior Scientist, Automation and HTS - Target Discovery & Biology (TD&B)What you will doLet’s do this. Let’s change the world. In this vital role you will leverage...SeniorFull timeRemote workFlexible hours- Amgen in Thousand Oaks, CA is seeking a Senior Scientist in Functional Genomics to drive genome engineering for target discovery and validation. You will design and apply viral vector technologies (AAV, lentiviral) in multidisciplinary discovery teams, translating complex...Senior
- Amgen Inc. (IR) in Thousand Oaks recruiting a Senior Scientist to lead automation for functional genomics screens and multi-omics integration... ...therapeutic areas, optimize imaging assays, and advance target discovery strategies in a fast-paced, science-driven environment...Senior
- Amgen in Thousand Oaks, CA, is seeking a Senior Scientist in mass spectrometry-based proteomics to join a collaborative team. You will deliver insights to support target identification and drug discovery, while advancing proteomics platforms. The role includes developing...Senior
- Amgen Inc. (IR) in Thousand Oaks seeks a Senior Scientist to drive automation and HTS for target discovery and biology. You will lead automation pipelines, translate manual protocols to 96- and 384-well formats, and optimize imaging and data analysis in state-of-the-art...Senior
- Target PR Range: 22-32/hr DOE Job Details Onsite Education/Experience: Bachelor’s degree with approximately 5 years of relevant laboratory experience. Position Summary Perform GMP analytical testing in support of synthetic drug substance, drug product, raw material, stability...Senior
$127.12k - $171.99k
...the world. We are seeking a motivated Senior Scientist in mass spectrometry-based proteomics... ...deliver critical insights to support target identification and drug discovery,... ...reproducible results. Knowledge of targeted protein degradation or E3 ligase biology is a plus What...SeniorFull timeFlexible hours- Amgen, based in Thousand Oaks, seeks a Principal Scientist to lead early validation efforts for membrane protein targets. You will guide cell-based and quantitative assays, partner with cross-functional teams, and drive robust, scalable workflows across discovery programs...
- ....) and experience with relevant analytical techniques (i.e. SEC, CEX, HIAC, MFI)* Understanding of physical/chemical stability of proteins and how process-related stresses impact molecule attributes and product quality. Familiarity with ADCs is preferred.* Proficiency...Senior
- Amgen in Thousand Oaks, CA is seeking a Senior Scientist to advance synthetic biology, molecular engineering and NGS within our Protein Therapeutics team. You will help develop and deploy novel workflows that enable rapid, scalable design of complex biologic molecules in...Senior
- ...This Senior Scientist role focuses on identifying therapeutic targets and conducting preclinical research in cardiometabolic disease, particularly osteoporosis and metabolic disorders. The position involves designing and executing in vitro and in vivo studies, analyzing...Senior
- ...patients while transforming your career. Process Development Senior Principal Scientist What You Will Do Let’s do this. Let’s change the world.... ...of linker‑payload attributes, stability/process‑relevant degradation pathways, and analytical strategies used to characterize...SeniorFlexible hours
- ...Senior Scientist role focused on developing automation strategies for functional genomics screening and high-throughput target discovery. The position involves integrating advanced in vitro models, multi-omics profiling, and automation platforms to accelerate biological...Senior
$34.76 per hour
...Job Description Aptask Global Workforce (AGW) is seeking a Scientist Senior Associate for a contract position with a Global Biotechnology... ...HIAC, MFI) Understanding of physical/chemical stability of proteins and how process-related stresses impact molecule attributes and...SeniorHourly payContract work$157.74k - $213.41k
...as part of the Amgen team. Join us and transform the lives of patients while transforming your career.Process Development Senior Principal Scientist BioconjugatesWhat you will doLet’s do this. Let’s change the world. In this vital role you will Amgen’s DSTS group within...SeniorFull timeFlexible hours- Aptask Global Workforce (AGW) is seeking an Associate Scientist - Onsite for a 12+ month contract in Thousand Oaks, CA. The role sits in a state-of-the-art Protein Chemistry team within a multidisciplinary Protein Therapeutics group, and requires a strong biochemistry background...Contract work
- Amgen in Thousand Oaks, CA or Cambridge, MA seeks a Process Development Senior Principal Scientist in Bioconjugates to lead a multidisciplinary team developing sustainable oligonucleotide manufacturing processes, driving capacity expansion, and guiding tech transfers....Senior
- Amgen, located at the Thousand Oaks, CA campus, seeks a Senior Principal Scientist to lead bioconjugate process development. You will guide a multidisciplinary team to develop scalable manufacturing processes for ADCs, driving innovation and ensuring regulatory readiness...Senior
$127.12k - $171.99k
...transform the lives of patients while transforming your career.Senior Scientist - Cardiometabolic DisordersWhat you will doLet’s do this. Let... ...to conduct biology research and identify therapeutic targets in cardiometabolic disease that are tractable and offer the opportunity...SeniorFull timeFlexible hours- Amgen is seeking a Process Development Senior Principal Scientist in Thousand Oaks, CA to lead drug product design, formulation, and process development for biologics and ADCs. You will guide diverse teams through scale‑up, characterization, and regulatory readiness to...Senior
$130.38k - $176.4k
...patients while transforming your career.Sr. Scientist- PKDM-BA (Immunoassay)What you will... ...motivated and scientifically rigorous Senior Scientist - Non-Regulated Immunoassays... ...immunoassays used for pharmacokinetic and soluble target protein measurements.The successful candidate...SeniorFull timeContract workFlexible hours- ..., youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior Principal Scientist What You Will Do Lets do this. Lets change the world! We are seeking an experienced toxicologist in the Product Stewardship...SeniorWork at officeRemote workFlexible hours
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