Synthetic Chemist
$150k - $200kApproach Venture
Synthetic Chemist - Develop the Chemistry Behind Next-Generation Energetics ManufacturingWaltham, Massachusetts | On-siteOpportunity SummaryJoin an early-stage defense technology company developing advanced chemical manufacturing systems for critical energetic materials. The company is combining chemistry, automation, and continuous processing to increase domestic production capacity for materials used across defense applications. As a Synthetic Chemist, you will own hands-on chemistry development at the front end of the technical pipeline. You will design and execute experiments, develop and optimize synthetic routes, investigate reaction mechanisms, and build the technical understanding required before chemistry moves into pilot-scale production. This is a highly experimental role centered on synthesis, reaction development, and problem solving at the bench. You will work closely with process development engineers and chemists to ensure laboratory discoveries can ultimately translate into safe, repeatable, and scalable manufacturing processes.About UsWe are a venture-backed defense manufacturing startup developing modular, highly automated production systems for energetic materials. The team is building new approaches to chemical manufacturing that combine continuous processing, advanced chemistry, and automation to improve production speed, safety, consistency, and scalability.Job DutiesDesign and execute laboratory experiments to develop and characterize chemical reactionsDevelop, evaluate, and optimize synthetic routes and reaction conditionsUse structured experimental approaches, including DoE and parametric studies, to understand key reaction variablesInvestigate reaction mechanisms, impurities, failure modes, and competing chemical pathwaysGenerate reliable experimental data that informs reaction design and future scale-upDevelop and apply analytical methods to evaluate reaction performance and product characteristicsUse tools such as NMR, HPLC, GC-MS, FTIR, and related techniques to support chemistry developmentWork closely with process development teams as chemistry transitions from flask and small-reactor experiments toward pilot-scale systemsEvaluate thermal behavior, chemical stability, and process hazards throughout developmentTroubleshoot reactions, laboratory equipment, and experimental systemsIdentify opportunities to simplify chemistry, processing steps, and experimental workflowsClearly document results and communicate technical recommendations across chemistry and engineering teamsQualificationsBachelor's, Master's, or PhD in Chemistry, Organic Chemistry, Synthetic Chemistry, Catalysis, or a related field5+ years of professional experience in synthetic chemistry, reaction development, or closely related experimental R&DStrong hands-on experience with benchtop chemical synthesisExperience designing and optimizing reactions rather than primarily executing established proceduresStrong understanding of reaction chemistry, experimental design, and laboratory practicesWorking knowledge of analytical techniques such as NMR, HPLC, GC-MS, or FTIRStrong experimental troubleshooting and problem-solving skillsAbility to operate independently in a hands-on laboratory environmentAbility to lift up to 50 poundsAbility to work on-site and travel as neededMust meet applicable U.S. export-control requirements and be eligible to obtain a U.S. security clearancePreferred ExperienceContinuous-flow chemistry or flow reactor developmentReaction scale-up from benchtop experiments into larger laboratory or pilot systemsProcess chemistry or chemical process developmentNitration chemistry or other highly exothermic reactionsExperience working with energetic, hazardous, reactive, or toxic materialsAnalytical method development using HPLC, IC, NMR, ICP-OES/MS, DSC/TGA, or related techniquesExperience within pharmaceuticals, specialty chemicals, fine chemicals, energetics, propellants, explosives, or other chemistry-intensive manufacturing environmentsExperience working closely with process development or chemical engineering teams to transition chemistry toward productionWhy Join UsThis role offers significant ownership over chemistry that is intended to move beyond laboratory research and into real-world production.You will work at the point where fundamental chemistry decisions are made, with direct visibility into how your experimental work influences process development, pilot-scale systems, and future manufacturing.The environment is hands-on and highly technical, with close collaboration across chemistry, process engineering, automation, and hardware development.Early-stage equity and competitive benefits.Compensation Details$150,000 - $200,000
$140k - $200k
...production to meet the munitions demands of the US and Allies safely, rapidly, and cost effectively. Summary We are seeking a synthetic chemist to lead small-scale chemistry characterization and development. This role is the front end of ATP's technical pipeline: you...SuggestedPermanent employment$115k - $165k
...designing and building new organisms. Senior Engineer I, Computational Synthetic ChemistBoston, MassachusettsAbout Ginkgo DatapointsGinkgo... ....The Small Molecules team is looking for a synthetic organic chemist to support computationally enabled synthetic chemistry. This role...SuggestedWork at office- We are seeking a passionate PhD-level synthetic chemist to drive the discovery of small molecules for next-generation 3D printing resins . This position involves rapid exploration of chemical space through organic synthesis to develop photochemical and photophysical structure...Suggested
$120k - $145k
...munitions demands of the US and Allies safely, rapidly, and cost effectively. Summary We are seeking an experienced analytical chemist who will own the product characterization and testing function. This functions stands between process R&D and final product...SuggestedPermanent employment$120k - $160k
...Job Description Job Description Analytical Chemist - Build the Chemistry Behind Next-Generation Manufacturing Waltham, Massachusetts | On-site Opportunity Summary Join an early-stage advanced manufacturing company developing new chemical production processes...Suggested- ...Senior Chemist Osmoses Inc. is a technology company revolutionizing the way industrial separations are performed today! Industrial... ...the chemistry team. What We're Looking For ~ PhD in synthetic chemistry, polymer science, or a related field or equivalent experience...Contract workWork at officeWorldwide
$100.5k - $145.17k
Job title : Senior Analytical Chemist - Solid State Characterization Location: Cambridge, MA About the job Sanofi is seeking a highly... ...for Solid State Characterization. The group is part of the synthetic platform within Global CMC Development that is striving to become...$130k - $200k
...the munitions demands of the US and Allies safely, rapidly, and cost effectively. Summary We are seeking a process development chemist to own and execute the research, development, optimization, and piloting of our energetic materials synthesis. This position will...Permanent employment- The mission of the Advanced Materials and Microsystems Group in the Advanced Technology Division is to research and develop a broad array of electronic, electro-optic, and RF materials and devices to develop leap-ahead capability in support of national security. Our materials...
$110.51k - $141.56k
...Scientist for Chemistry to propose and characterize molecules as potential therapeutics for oncology. The role includes designing synthetic routes, solving purification challenges, and conducting data-driven decisions in drug discovery. Candidates should possess a PhD in...$94k - $115k
Job Description:Analytical Chemist - 2nd ShiftBurlington, MAABOUT THE COMPANY:QSA Global, a division of Illinois Tool Works (ITW), specializes in supplying state-of-the-art gamma radiography and portable X-ray systems used in non-destructive testing (NDT), as well as high...Work experience placementLocal areaAfternoon shift- ...Description PsiThera is seeking a talented and creative medicinal chemist with strong hands-on experience advancing discovery programs... ...nomination. This candidate will bring deep expertise in synthetic and medicinal chemistry, with a demonstrated track record optimizing...
- ...information on our technology and our vision. Verdox seeks a Polymer Chemist to join our R&D team. Key Responsibilities Design and... ...purification techniques Focus on developing and optimizing synthetic protocols for cost-effective polymer synthesis and...
$81.2k - $150.8k
Job Description SummaryWe are seeking a highly talented and motivated synthetic / medicinal chemist to join the Synthesis Technologies Team within Global Discovery Chemistry group at BioMedical Research (NIBR) at our Cambridge, MA site.Job DescriptionInternal Job Title:...Full time- ...scale, collaborate with global teams, and contribute to the discovery of transformative medicines. The role requires a BS or MS in synthetic organic chemistry with 2-5 years of postgrad experience, strong data management, and a mindset toward green synthesis practices....
- Wellesley College invites applications for a tenure-track Assistant Professor of Chemistry in synthetic organic chemistry, beginning Fall 2027. The candidate will teach introductory chemistry, organic chemistry courses and labs, and advanced seminars, while developing curricular...
- Yoh Life Sciences in Cambridge, MA, is hiring an Organic Chemist / Platform Chemistry Scientist for the Encoded Technologies team. This... .... The ideal candidate will independently plan and execute synthetic experiments, troubleshoot complex reactions, and collaborate across...Contract work
$100k - $120k
...Analytical Chemist Boston, MA ( Description Living Proof is seeking an experienced and hands-on Analytical Chemist to join the R&D Research team. Responsibilities include analytical method development and validation, investigating complex analytical problems, supporting...Full timeContract work$110.51k - $141.56k
...optimizing the potency, pharmacokinetics, safety and in vivo efficacy of potential oncology drugs. Responsibilities Design and improve synthetic routes to support SAR studies in a timely manner. Solve synthetic, characterization and purification challenges of complex...$66.8k - $124k
Medicinal Organic Chemist - Chemical Biology (BS or MS) Job ID REQ-10085277 Aug 13, 2026 USA Summary The Discovery Sciences team is seeking... ...synthesesof small molecules Analyze and interpret data,solve synthetic issues and design follow-up experiments Collaborate with peers...$45 - $49.5 per hour
Yoh Life Sciences is seeking an Organic Chemist / Platform Chemistry Scientist to support a leading pharmaceutical company's Encoded Technologies... ...experimental chemist who can independently plan and execute synthetic chemistry experiments, troubleshoot challenging reactions,...Contract workMonday to Friday$66.8k - $124k
...based on team or individual hypotheses and perform multi-step syntheses of small molecules. Analyze and interpret data; troubleshoot synthetic issues; design follow-up experiments. Collaborate effectively as part of a cross-functional team. Adhere to laboratory safety...- ...scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today. We are seeking a motivated Strain and Enzyme Scientist to help advance the development of natural BioAlternatives...Full timeFlexible hours
$50 per hour
...into an innovative lab environment in Cambridge, MA, with a top-tier global pharmaceutical leader. We are seeking a dedicated Organic Chemist to join the Encoded Technologies team onsite, playing a key role in advancing on-DNA binder confirmation platforms and driving...Hourly payContract workTemporary workWork experience placement$70k - $90k
...Compassion • Be Resourceful • Listen • Hustle Who We Are Looking For: Phoenix Tailings is looking for an R&D Analytical Chemist to help drive the analytical backbone of our clean metals production technology. This role is for someone who can operate with...Full time$91.5k - $95k
Shift: Monday through Friday, 8:00AM - 5:00PM Are you ready to work making the world a safer, healthier place? Join our mission to continuously move science forward; to innovate and advance all aspects of our business to improve the health and safety of our communities...Full timeWork at officeLocal areaImmediate startMonday to FridayFlexible hoursShift work$36 - $40 per hour
...Overview: Business Title: Chemist II - RNA Synthesis Position Title: Analyst II Division: Consumer Products Services Entity: Consumer Products Services/ATL Location: Boston, MA Reports to: Manager FLSA: Non-exempt Hours Worked:Typically,...Hourly payLive outWork at officeMonday to FridayFlexible hours- A Chemtek is seeking a detail-oriented Analytical Chemist to support the testing, characterization, and documentation of analytical reference materials. This role will play an important part in maintaining product quality and supporting our quality systems. The Analytical...Worldwide
- Mariana Oncology, Inc. seeks an experienced Radiochemist to advance personalized medicine and radiopharmaceuticals in a lab-based role. You will develop and optimize radiolabeling methods for new product candidates, address stability and PK questions, and support in vivo...
- Novartis Institutes for BioMedical Research, Inc. in Cambridge, MA seeks a Research Scientist II in Synthesis Technologies to join Global Discovery Chemistry. You will develop and characterize small molecules, collaborating across disciplines to advance drug discovery....
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Synthetic Chemist. Be the first to apply!


