ADP Payroll Manager - Multi-State & 401(k) Expert

The Payroll Manager will oversee and manage the company’s end-to-end payroll operations while serving as the internal subject matter expert on ADP Workforce Now, the organization’s enterprise payroll platform. This role ensures accurate payroll processing, oversees payroll tax compliance, time and attendance administration, reporting, and payroll-related system improvements in ADP Workforce Now. Payroll Processing Manage the full payroll cycle including preparation, processing, review, and reconciliation of payroll. Perform payroll pre-processing activities in collaboration with HR including employee data updates, prorations, compensation changes, deductions, garnishments, and tax levies. Process supplemental earnings such as bonuses and commissions. Calculate manual checks and process off-cycle payroll runs when required. Review, audit and approve time & attendance hours within the payroll system Prepare and distribute payroll post-processing reports. Payroll Tax & Compliance Manage payroll tax setup and maintenance across federal, state, and local jurisdictions. Establish tax accounts when employees are hired in new states or municipalities. Review and respond to payroll tax notices, amendments, and agency inquiries. Support monthly payroll reconciliations and quarterly tax reporting adjustments. Benefits & Retirement Plan Administration Administer payroll-related aspects of the company’s 401(k) plan in Paychex, including employee onboarding, contribution updates and coordination with plan providers. Ensure proper handling of payroll deductions, including benefits and wage garnishments. Systems & Process Improvement Serve as the primary administrator of payroll systems. Evaluate payroll providers and recommend improvements to payroll processes and systems. Lead or support payroll-related system implementations and integrations. Employee & Cross-Functional Support Assist with payroll-related aspects of employee onboarding, including tax forms and direct deposit setup. Maintain employee payroll records and updates. Partner with HR and Finance to ensure payroll accuracy and compliance. Qualifications 4–8+ years of payroll processing experience in a multi-state environment. Strong knowledge of payroll taxes, compliance, and reporting requirements. Experience processing payroll for salaried and hourly employees. Demonstrated expertise in ADP Workforce Now is required. Experience with 401(k) payroll administration and payroll tax notice resolution is a plus. Strong attention to detail, organizational skills, and ability to manage strictly confidential information. Possesses a proactive, hands-on mindset with a willingness to contribute beyond core responsibilities and support additional projects and operational priorities as they arise. Comprehensive Medical, Vision and Dental benefits Generous Paid Time Off and Holiday Schedule LifeSci Partners is proud to be an Equal Opportunity Employer. We do not discriminate based on race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), national origin, age, disability, veteran status, or any other protected status under federal and law. We provide reasonable accommodation for applicants with disabilities or sincerely held religious beliefs, as required by law. #J-18808-Ljbffr LifeSci Partners LLC