VP, Clinical Systems and Process Enablement

Vice President, Pipeline Delivery Systems & Process Enablement

Pipeline Delivery Systems & Process Enablement is a strategic leadership role responsible for building and scaling a seamless, integrated ecosystem of systems, data, and operational processes that enable efficient and predictable delivery of Alnylam's development pipeline. This leader will drive operational excellence across Clinical Operations, Data Management, and Program Management, ensuring that systems and processes are standardized, user-centric, and enable real-time, data-driven decision-making. Through strong leadership in process design, training, and change management, this role ensures consistent adoption and sustained performance, accelerating the delivery of RNAi therapeutics to patients.

Key Responsibilities

• Systems & Digital Enablement Strategy
• Process Excellence & Standardization
• Operational Performance & Continuous Improvement
• Training & Capability Building
• Change Management & Adoption
• Cross-Functional Integration
• Organizational Leadership

Qualifications

• BS/MS in Life Sciences, Engineering, Information Systems, Business, or a related field.
• 20+ years of experience in biotech/pharma, with leadership roles in clinical systems, operations, process excellence, or digital enablement.
• Demonstrated experience operating at the enterprise or portfolio level, supporting complex, multi program clinical pipelines.
• Proven track record implementing enterprise systems and process transformations in R&D or Clinical Development (e.g., CTMS, eTMF, data platforms, reporting and analytics).
• Experience driving large-scale change management and adoption initiatives.
• Experience partnering closely with IT, Digital, and Data organizations to deliver scalable, user-centric solutions.
• Expertise establishing performance management frameworks, including KPIs, dashboards, and operational metrics to support portfolio and program decision-making.
• Strong continuous improvement mindset, with experience leading initiatives that improve cycle times, data quality, and execution predictability.
• Strong understanding of clinical development processes, data flows, and regulatory requirements.
• Strong capability in organizational change management, including stakeholder engagement, communication planning, and adoption measurement.

U.S. Pay Range $301,800.00 - $408,200.00