Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Python Backend Engineer

$85 - $95 per hour

3Pillar Global

Accomplished Tech Visionary

Elevate your expertise to new heights at 3Pillar, the premier destination for trailblazing senior engineers like yourself. Picture collaborating with industry leaders and spearheading transformative projects that directly impact global clinical trial outcomes. Our mission is to revolutionize healthcare technology, and your skills are integral to achieving this ambitious goal.

Your role extends beyond writing code; you will architect scalable backend services for the BX platform and guide a team of engineers in delivering cloud-native, Python-based systems built for the demands of clinical research. Join us and spearhead the charge toward a tech future that transcends the ordinary.

You will be focused on leading the development of Python backend services running on AWS, managing PostgreSQL databases, architecting Kubernetes-based infrastructure, and ensuring seamless cloud-to-cloud integrations critical to the BX platform.

Key Responsibilities

  • Facilitate effective communication with client project stakeholders regarding project status and technical recommendations.
  • Lead the design and development of backend services and APIs using Python and the Pyramid framework on AWS.
  • Architect and manage PostgreSQL schemas, queries, and performance optimizations for clinical-grade data.
  • Build and maintain AWS infrastructure including Kubernetes (EKS), Lambda, API Gateway, and cloud-to-cloud integration patterns.
  • Define backend coding standards, API design patterns, security best practices, and testing strategies.
  • Mentor and guide backend engineers, driving engineering excellence across the team.
  • Engage in agile software development including stand-ups, sprint planning, retrospectives, and estimation.
  • Independently drive project delivery within defined architecture, demonstrating autonomy from conceptualization to deployment.

Minimum Qualifications

  • Experience/expertise in the following areas specified below:
    • Design and implement scalable backend services and APIs using Python
    • Architect PostgreSQL databases with strong skills in schema design, query optimization, and data integrity
    • Utilize AWS services: Kubernetes (EKS), Lambda, API Gateway, RDS, S3, IAM, and cloud-to-cloud integrations
    • Mentor engineers, conduct code reviews, and enforce engineering standards across the team
    • Deliver production systems with high reliability, observability, and security
  • Must-Have Skills & Tools:
    • Languages: Python, JavaScript, SQL, REST API
    • OAUTH 2
    • Docker
    • Database: PostgreSQL (advanced — schema design, performance tuning, stored procedures)
    • Cloud: AWS – Kubernetes (EKS), Lambda
    • Tools: Jira, Bitbucket/GitHub, Slack/Teams
  • Good to Have Skills:
    • Framework: Pyramid (Python web framework)
    • VsCode
    • Typescript
    • Snowflake
    • SQL Alchemy (ORM)
    • 6+ years of backend engineering experience, including 2+ years in a lead or tech lead role.
    • Strong understanding of SOLID principles, OOP, and clean architecture patterns.
    • Familiarity with OWASP security practices.
    • English proficiency.

Additional Experience Desired

  • Experience with clinical or healthcare data systems (HL7, FHIR, GxP, 21 CFR Part 11).
  • Knowledge of microservices and serverless architectural patterns.
  • Experience with Docker, container orchestration, and modern CI/CD tooling.
  • Proficiency with unit testing, integration testing, and TDD practices.

What is it like working for 3Pillar Global?

At 3Pillar, we offer a world of opportunity:

  • Imagine a flexible work environment – whether it's the office, your home, or a blend of both. From interviews to onboarding, we embody a remote-first approach.
  • You will be part of a global team, learning from top talent around the world and across cultures, speaking English everyday.
  • We're big on your well-being – as a company, we spend a whole trimester in our annual cycle focused on wellbeing. Whether it is taking advantage of fitness offerings, mental health plans (country-dependent), or simply leveraging generous time off, we want all of our team members operating at their best.
  • Our professional services model enables us to accelerate career growth and development opportunities – across projects, offerings, and industries.
  • We are an equal opportunity employer. It goes without saying that we live by values like Intrinsic Dignity and Open Collaboration to create cutting-edge technology AND reinforce our commitment to diversity – globally and locally.

Join us and be a part of a global tech community! Check out our Careers page to learn more about what it's like to be part of our #oneteam!

Benefits

  • Medical Insurance benefits as per company policy.
  • Dental insurance as per company policy.
  • Vision insurance as per company policy.
  • Employer paid Disability, Life, and AD&D insurance
  • Unlimited PTO
  • Paid parental leave
  • 401K
  • Flexible work policy
  • 12 Paid Holidays

$85 - $95 an hour

Vacancy posted 3 days ago
Similar jobs that could be interesting for youBased on the Senior Python Backend Engineer in United States vacancy
  •  ...headquartered in the San Francisco Bay Area, and we’re looking for a Senior Backend Engineer to work closely with the founders on both product...  ...years building production web applications 3+ years with Python and Django Celery, RabbitMQ, and Redis in production (day... 
    Senior
    Full time
    Remote work

    Commit

    San Francisco, CA
    4 hours ago
  •  ...they are expanding their technology team and are hiring a Senior Backend Software Engineer. The Senior Backend Software Engineer with at least...  ...specific hands-on experience and expertise with the following: Python, PostreSQL, AWS, and any additional experience with AI... 
    Senior
    Work at office
    Immediate start

    The Cypress Group

    White Plains, NY
    5 days ago
  • $36k - $96k

    Join to apply for the Senior Backend Engineer - Python role at Lumenalta This range is provided by Lumenalta. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more. Base pay range $36,000.00/yr - $96,000.00/yr What We’re Working... 
    Senior
    Full time
    Contract work
    Remote work
    Monday to Friday
    Flexible hours

    Lumenalta

    Tulsa, OK
    2 days ago
  • $160k - $260k

     ...remote team as well. About the role We are looking for a Senior Backend engineer passionate about building robust, scalable distributed systems...  ...Expertise in Kubernetes (K8s) and Docker Proficiency in Python and Node.js for building and maintaining APIs and services... 
    Senior
    Full time
    Work at office
    Remote work

    Mathpix

    New York, NY
    5 days ago
  •  ...About the Role We are seeking a skilled and passionate Back-End Engineer with a strong background in data engineering to join our...  ...Responsibilities Design, develop, and maintain data pipelines using Spark, Python, Scala, and Java. Write efficient and optimized SQL queries... 
    Senior
    Hourly pay
    Permanent employment
    Contract work
    Local area

    Robotics Technologies LLC

    Elk Grove, CA
    1 day ago
  •  ...designed and constructed. If you enjoy solving "real-world" problems where code meets concrete, this is your spot. As a Senior Python Backend Engineer at AIAEC, you will be a key architect and builder of ChatAEC and our suite of AI-driven civil engineering tools. You... 
    Senior

    AIAEC LLC

    Phoenix, AZ
    5 days ago
  •  ...Science or a related field. ~Strong Python coding skills - 7+ years. ~2+ years of...  ...production LLM systems. ~Experience building backend APIs with FastAPI, async patterns, rate...  ..., AWS or GCP; ~Experience in data engineering in Big Data systems including: Large-... 
    Senior
    Full time
    Flexible hours

    Intellectsoft

    Remote
    8 hours ago
  • $1,000 - $2,030 per month

     ...What you'll do As a Software Engineer on the Otter Marketing/Boost team, you'll...  ...and goals into real orders. Build backend services for campaign management, budgeting...  ...purpose backend language (e.g., Java, Go, or Python). Solid foundation in distributed systems... 
    Senior
    Full time
    Temporary work
    Work at office
    Flexible hours

    Otter

    Seattle, WA
    1 day ago
  • $100k - $112k

     ...Senior Backend Engineer– Remote Bright Vision Technologies is a technology consulting and software development company delivering cloud, AI, data, and enterprise solutions across the United States. This is a fantastic opportunity to join an established and well-respected... 
    Senior
    Full time
    H1b
    Local area
    Immediate start
    Remote work
    Visa sponsorship

    Bright Vision Technologies

    United States
    2 days ago
  • $160k - $180k

     ...tech. Position Overview Scotch is hiring an experienced backend-leaning full stack engineer to own features end-to-end across our Rails + Hotwire...  ...architecture on top of standard feature delivery. It's a senior individual contributor role, not a management position,... 
    Senior
    Full time
    Flexible hours
    Shift work

    Scotch

    United States
    1 day ago
  • $140k - $160k

     ...Technology Fast 500 again in 2024, but we're just getting started. Location: Remote How You'll Make an Impact: As a Senior Backend Engineer on the Booking Engine squad, you'll implement new architectures, features, and best practices to scale the Cloudbeds platform... 
    Senior
    Full time
    Work at office
    Local area
    Remote work
    Work from home
    Worldwide
    Home office
    Weekend work

    Third-Party Job Posts

    United States
    2 days ago
  • $155k - $211k

     ...--------------------------------------- Job Application Deadline: 08/31/2026 The Opportunity DAT is hiring a Senior Backend Software Engineer to join the Broker Tech team building the Convoy Platform, a digital freight marketplace that connects brokers and carriers... 
    Senior
    Full time
    Temporary work
    For contractors
    Work experience placement
    Work at office
    Local area
    Immediate start
    Flexible hours

    DAT

    Seattle, WA
    1 day ago
  •  ...exceptional people. About the Role As a Senior Software Engineer at Mercor, you’ll take end-to-end...  ..., build, and scale production-grade backend APIs, services, and infrastructure....  ...For Strong coding fundamentals in Python (our primary backend), though interviews... 
    Senior
    Full time
    For contractors
    Immediate start

    Mercor

    San Francisco, CA
    8 hours ago
  • $126k - $248k

     ...developers and other end-users. Our senior engineers are typically specialists in a particular...  ...open source libraries for the Python ecosystem developers that use MongoDB....  ...libraries (PyMongo [ Django MongoDB Backend [ PyMongoArrow [ LangChain MongoDB [... 
    Senior
    Full time
    Local area
    Worldwide
    Flexible hours

    MongoDB

    San Francisco, CA
    3 days ago
  • $163k - $246.5k

     ...Dropbox. Learn more at semgrep.dev. About the role As a Backend Engineer, you'll work on our backend and infrastructure systems to...  ...Our stack utilizes Typescript and React on the Frontend, Python, Flask and SQLAlchemy on the Backend, is deployed via Kubernetes... 
    Senior
    Full time
    Currently hiring
    Local area
    Remote work
    Weekend work
    3 days per week

    Semgrep, Inc.

    San Francisco, CA
    8 hours ago
  •  ...improve society, and can demonstrate the right set of software engineering skills to effectively develop robust and scalable applications...  ...Minimum 6 years of demonstrable experience building intricate backend systems Solid SQL and noSQL database experience (Postgres,... 
    Senior
    Remote job
    Full time

    Entefy

    Remote
    8 hours ago
  •  ...Francisco-based 200 person venture. They are looking for a Python, Backend Engineer to join them in San Francisco on a hybrid basis. As an...  ...please apply & we'll reach out! *NOT a Data Scientist position Seniority level Mid-Senior level Employment type Full-time Job... 
    Full time

    Goliath Partners LP

    San Francisco, CA
    2 days ago
  • $165k - $195k

     ...SITE Technologies is seeking a thoughtful and versatile Senior Backend Software Engineer to help build and evolve SITE's platform and related customer...  ...maintain core backend APIs and services, primarily in Python and FastAPI ~ Translate complex product workflows into... 
    Senior
    Remote job
    Full time
    Temporary work

    Site Technologies

    Chicago, IL
    8 hours ago
  •  ...Job Title Senior Backend Engineer - AI Enablement & Strategy Overview Sephora is seeking a highly proactive, strategic Senior Python Backend Engineer with strong AI exposure to help teams do more with less by improving systems, workflows,... 
    Work at office

    BayOne Solutions

    San Francisco, CA
    5 days ago
  •  ...Python Backend Engineer We are seeking a highly skilled Python Backend Engineer with 6 to 10 years of experience to join our dynamic team. The ideal candidate will have expertise in Python, AI and Client concepts, API development, and NLP. This role involves developing... 

    Keylent Inc

    Phoenix, AZ
    2 days ago
  • $180k - $210k

     ...Millennial Software is seeking a Senior Backend Software Developer to join our collaborative...  ...reliability while partnering with frontend engineers, analysts, and users.  The ideal...  ...in at least one backend language (e.g., Python, Java, Go, C#, Node.js) and common frameworks... 
    Senior
    Full time

    Millennial Software Solutions

    Remote
    8 hours ago
  •  ...operators get patients the right care, at the right time, in the right setting. Role Description We’re seeking a Senior Backend Engineer with a passion for systems architecture, data modeling, and large-scale workflow orchestration . In this role, you’ll... 
    Senior
    Full time
    Work at office

    Tennr

    Remote
    8 hours ago
  • $150k - $190k

    Swish Analytics, located in San Francisco, is seeking a backend engineer to design, build, and optimize core API services. The ideal candidate...  ..., along with proficiency in languages like NodeJS and Python. The position offers a competitive salary range of $150,000 -... 
    Senior

    Swish Analytics

    San Francisco, CA
    15 hours ago
  •  ...Python Backend Engineer Location: San Jose (CA), Onsite @ San Jose, CA is mandatory Role Overview: We are looking for a Python Backend Engineer to build the backbone of our platform. You will be responsible for creating high-performance APIs, integrating advanced... 

    E-Solutions

    San Jose, CA
    2 days ago
  •  ...Black Cape  Title: BackEnd Software Engineer (2+ years - Senior Level) Locations: Arlington, VA, Reston, VA and areas throughout the DMV area...  ...and deploying AI/ML solutions using Google TensorFlow, Python scikit-learn, and other tools. Black Cape’s approach to... 
    Senior
    Full time
    For subcontractor

    Black Cape

    Remote
    8 hours ago
  •  ...Cloud-Native Backend Developer Duration: 6+ months Location: Philadelphia, PA | Columbus, OH | Nashville, TN | Dallas, TX | Tampa,...  ...Develop secure, high-performance APIs and microservices using Python while leveraging AWS Lambda and modern database technologies. Contribute... 

    The Brixton Group, Inc.

    Philadelphia, PA
    5 days ago
  •  ...for a thrilling adventure. As a Software Engineer, you'll play a vital role in our dynamic...  ...with at least 8+ years of experience in Python, REST API and SQL. Expertise with Git source...  .... Experience in building frontend/backend applications at scale. Proficiency in the... 
    Senior

    3Pillar

    New York, NY
    5 days ago
  • $130k - $220k

     ...systems. Working alongside software, hardware, and systems engineers, you’ll design and operate the backend services and cloud infrastructure that ingest,...  ...Experience in one or more of the following is a plus: Python and modern backend development. Azure or another... 
    Senior
    Permanent employment
    Full time
    Work experience placement
    Casual work
    Relocation package

    Chaos Industries

    San Francisco, CA
    8 hours ago
  • $170k - $180k

     ...Health is looking for a highly skilled Backend Software Engineer IV to design, build, and scale the...  ...initiatives end-to-end, working deeply with Python, Django, PostgreSQL, and Google Cloud...  ...-functional initiatives. ~ Deep, senior-level expertise in Python and the Django... 
    Senior
    Permanent employment
    Full time
    Local area
    Remote work
    Visa sponsorship
    Work visa

    Vida Health

    Remote
    8 hours ago
  •  ...days in-office culture. Both founders are technical. Every engineer on the team has experience at early-stage startups. Several...  ...to customers, make technical decisions, and ship.   Role: Senior Backend Software Engineer We're a tiny engineering team building something... 
    Senior
    Full time
    Work at office

    Alpaca Health

    New York, NY
    8 hours ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Python Backend Engineer. Be the first to apply!