(Senior) Director, FP&A

Job Description

Job Description

More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a late-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks.   With our purified, high-precision investigational cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.

Position Summary:  Reporting into our CFO & Head of Strategy, the (Senior) Director, FP&A (depending on experience) will lead financial planning, forecasting, and reporting at Orca Bio, building upon our existing FP&A processes to scale into a commercial-ready function. This individual will serve as the functional leader for FP&A and is a highly visible, hands-on leader responsible for evolving our structure, processes, and financial rigor in a fast-growing, pre-commercial biotech environment. The role partners closely with Clinical Development, R&D, Manufacturing Operations, Medical Affairs, and Commercial leadership to drive budgeting, forecasting, and decision support across the organization.

This position will focus on core FP&A responsibilities (budgeting, forecasting, and operational finance), while partnering with leadership and adjacent functions on longer-term strategic and valuation-related initiatives.

• Own company-wide budgeting, forecasting, and monthly/quarterly actuals analysis, including variance analysis vs. plan
• Own the company’s financial forecast and ensure accuracy, consistency, and alignment across functions
• Enhance existing FP&A processes, reporting cadence, and financial infrastructure to support commercial launch
• Lead financial planning across R&D, Clinical, Manufacturing, and Commercial functions
• Own commercial financial planning, including revenue forecasts, patient flow models, and demand assumptions, in close partnership with Commercial leadership
• Partner with Accounting to align on cost visibility, including manufacturing economics and COGS drivers
• Develop long-range financial models to support strategic planning, investment decisions, and Board-level discussions
• Partner with functional leaders to track performance against plan and drive accountability for financial targets
• Translate financial results into clear, actionable insights for executive leadership

• Bachelor’s degree in Finance, Accounting, Economics, or related field (MBA preferred)
• 12+ years of progressive FP&A experience, including leadership experience in a biotech or life sciences company, preferably with commercial launch experience
• Demonstrated experience building or scaling FP&A processes in a high-growth, small to mid-sized organization
• Experience partnering with commercial organizations, including revenue forecasting and launch planning
• Experience supporting clinical organizations, including clinical development forecasting and portfolio planning
• Familiarity with manufacturing environments; in-house manufacturing experience preferred
• Advanced financial modeling and analytical skills, with ability to translate data into business insights
• Prior experience in smaller or mid-sized biotech environments preferred; candidates should be comfortable operating with limited structure and high ownership

The anticipated annual salary range for this job is based on prior experience in the role/industry, education, location, internal equity, and other job-related factors as permitted by law. For remote-based positions, this range may vary based on your local market. Full-time employment positions will also be eligible to receive pre-IPO equity and annual bonus, in addition to competitive medical, dental, and vision benefits, PTO, 401(k) plan, life and accidental death and disability coverage, and parental leave benefits. Other perks include subsidized daily lunches and snacks at our on-site locations.

Who we are

We are driven by a passion for science and compassion for patients. We act with urgency to ensure our treatments are one day accessible to all who need them.

We live by our core values of passion, courage, and integrity. Excellence in our work means the chance to unlock a better quality of life for our patients, and with that comes tremendous responsibility.

We innovate on a path that hasn’t been paved. We embrace an entrepreneurial spirit and take calculated risks to achieve our mission. We aren’t afraid to ask “why not” and challenge the status quo.

We maintain a start-up culture of camaraderie and leadership by example, regardless of title.

We’re proud to be an equal opportunity employer, and recognize that celebrating our differences creates stronger, lasting solutions that better serve our team, our patients and their healthcare providers.

Notice to staffing firms

Orca Bio does not accept resumes from staffing agencies with which we do not have a written agreement and specific engagement for a particular opening. Our employment activities, inquiries and offers are managed through our HR/Talent team, and all candidates are presented through this channel only. We do not accept unsolicited resumes, and we rarely outsource recruitment.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.