Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Chief Of Staff

Prime Intellect

Chief Of Staff

Prime Intellect is building the infrastructure for decentralized AI. By enabling global collaboration in compute, code, and capital, we're accelerating the development of open-access AI models with a bold vision: AGI that benefits everyone.

We're hiring a Chief of Staff to work closely with our CEO, CTO, and COO. This role blends operational leadership with hands-on execution: you'll oversee day-to-day systems that keep the company running, while also taking on higher-leverage projects across hiring, culture, and partnerships.

You'll manage everything from building the go-to-market strategy to scaling workflows, supporting hiring, and building relationships with key stakeholders. The common thread: creating the environment and structure that allow the executive team and broader company to focus on building.

Team Building & Support

  • Lead hiring processes across operations, business, and legal functions.
  • Support and mentor team members to foster a collaborative, results-driven culture.
  • Identify resourcing gaps and ensure teams have the tools they need to succeed.

Growth Excellence

  • Build the go-to-market strategy for our new RL initiatives
  • Design and refine workflows that improve productivity and scalability.
  • Implement systems for continuous improvement across the organization.
  • Develop and track metrics to measure performance and identify improvements.

Stakeholder Engagement

  • Build strong relationships with investors, partners, and collaborators.
  • Serve as a point of contact for external inquiries and partnerships.
  • Support leadership in fundraising prep and investor communications.

Who You Are

  • Proven experience as Chief of Staff, venture investor or similar role in a fast-paced, high-growth tech environment.
  • Strong organizational skills and ability to juggle shifting priorities.
  • Comfortable working side-by-side with founders and senior leadership.
  • People-oriented and resourceful, with a bias for solving problems quickly
  • Strong track record of aligning teams to execute ambitious goals at scale.
  • Experience with hiring, team development, growth contracts and fostering high-performing teams.
  • Business acumen with experience in financial management and fundraising.
  • Outstanding communication and interpersonal skills, including executive-level reporting.

What We Offer

  • Competitive compensation, including generous equity compensation.
  • San Francisco HQ incl lunch and other benefits.
  • Visa sponsorship and relocation support for international candidates.
  • Quarterly team off-sites, hackathons, and growth opportunities.
  • A chance to shape the future of decentralized AI alongside a passionate, mission-driven team.

We recently raised $15mm in funding (total of $20mm raised) led by Founders Fund, with participation from Menlo Ventures and prominent angels including Andrej Karpathy (Eureka AI, Tesla, OpenAI), Tri Dao (Chief Scientific Officer of Together AI), Dylan Patel (SemiAnalysis), Clem Delangue (Huggingface), Emad Mostaque (Stability AI) and many others.

Vacancy posted 25 days ago
Similar jobs that could be interesting for youBased on the Chief Of Staff in San Francisco, CA vacancy
  •  ...running and grown a high-caliber team turning the art of sales into a scalable science. About the Role We're looking for a Chief of Staff who will operate as a true extension of the CEO. This is a rare opportunity to work directly alongside the CEO and gain an... 
    Suggested

    Nooks

    San Francisco, CA
    1 day ago
  •  ..., Coinbase, and Palantir, among others Build a massive, fast-growing business with billions in revenue The Role The Chief of Staff to the CEO is Garrett Lord's closest execution partner - the person who helps him get things done at extraordinary speed across... 
    Suggested
    Full time
    Freelance
    Internship
    Work at office
    Remote work
    Flexible hours

    Handshake

    San Francisco, CA
    2 days ago
  •  ...This is one of the most important roles within the company. As Chief of Staff, you will work closely with the CEO across many of the most important business functions - strategy, recruiting, operations, fundraising, culture, and more. We're willing to take 6 months to... 
    Suggested
    Relocation
    Visa sponsorship

    Superpower Health, Inc

    San Francisco, CA
    3 days ago
  •  ...Chief Of Staff Opportunity We're automating compliance for banks and fintechs with AI agents that work like human analysts. We're looking for a Chief Of Staff to work directly with the CEO — someone who can operate across every function of the business, make the founder... 
    Suggested
    Temporary work
    Work at office
    Relocation package
    Shift work

    Sphinx

    San Francisco, CA
    1 day ago
  •  ...backed by New Stack Ventures, Marlinspike, Humba Ventures, Amplify.LA, Crosscut Ventures, and Lux Capital. About the Role: Chief of Staff at Heliux will be directly responsible for leading business operations, running strategic projects, and supporting customer... 
    Suggested
    Permanent employment

    Heliux, Inc.

    San Francisco, CA
    3 days ago
  •  ...As Chief of Staff at Emanate, you'll work directly with the founder to turn company priorities into execution across hiring, operations, GTM, finance, and team systems. You'll bring structure to fast-moving work-streams, drive follow-through on critical decisions, and... 

    Emanate

    San Francisco, CA
    3 days ago
  • $281k - $330k

     ...highly strategic role, you will partner with executives and senior leaders both across the business and within the Product org. As Chief of Staff reporting directly to the CPO, you will have an immediate impact on our CPO's productivity from day one, streamlining... 
    Work at office
    Local area
    Immediate start
    Remote work
    Relocation
    Flexible hours
    3 days per week

    Checkr

    San Francisco, CA
    3 days ago
  •  ...backed by top-tier investors, and count global enterprises and Fortune 500 brands among their customers. The Opportunity As Chief of Staff, you will work directly alongside the CEO of a fast-growing AI infrastructure startup, operating as a high-caliber generalist... 
    Shift work

    Talentpluto

    San Francisco, CA
    2 days ago
  •  ...Chief Of Staff We're looking for a Chief Of Staff who is highly driven, organized, comfortable with ambiguity, and excited to join us in-person in San Francisco to help build and scale the company. You'll work directly with the CEO and set the cadence for how the... 

    Variance

    San Francisco, CA
    1 day ago
  •  ...the complexity. Tens of millions of transactions today, billions ahead. THE ROLE We're looking for a swiss army knife / Chief of Staff to work directly with our CEO at Sphere . You'll be an extension of Nick, helping him across GTM, Ops, Finance, Tax and more.... 
    Work at office
    Weekend work

    Sphere

    San Francisco, CA
    4 days ago
  •  ...processes, and drive execution in fast-paced startup environments ~ Experience managing internal operations, team coordination, or chief of staff responsibilities at high-growth companies ~ Strong analytical skills with ability to work across both quantitative analysis... 

    Cascading AI Inc

    San Francisco, CA
    22 hours ago
  • $130k - $170k

     ...demos, recruiting, and company-building - and we need someone to keep it organized and driving forward. About the Role As Chief of Staff at Droyd, you will work closely with leadership to keep the company running smoothly. This is a high-leverage operational role... 
    Full time

    Droyd Robotics

    San Francisco, CA
    2 days ago
  •  ...in size Build and run RevOps across our commercial and federal businesses What we're looking for ~1-5 years of past Chief of Staff/Operating experience ~ Scrappy entrepreneur mindset, bias to action ~ Willingness to move to sf and open to travel ~ Thrives... 
    For contractors

    Usul

    San Francisco, CA
    2 days ago
  •  ...advising, may also manage an independent program and / or professional staff engaged in a range of administrative functions. Under the...  .... Partnering with Vice and Associate Chairs, Division Chiefs and Administrative Directors, ensures consistent interpretation... 
    Contract work
    Temporary work
    Work experience placement
    Work at office
    Worldwide

    University of California , San Francisco

    San Francisco, CA
    3 days ago
  • $500 per month

     ...Chief Of Staff — Office Of The CEO Giga has recently raised a $61M Series A and is working with Fortune 500 customers to deploy the next generation of customer experience - real-time AI agents that can understand emotion, resolve issues instantly, and scale across... 
    Temporary work
    Live in
    Work at office

    Giga AI, Inc.

    San Francisco, CA
    2 days ago
  •  ...Chief of Staff San Francisco, California Full Time As Chief of Staff, you'll partner closely with the leadership team to drive strategy, execution, and team growth. This is a high-impact role where you'll align teams, optimize operations, and tackle critical... 
    Full time
    Contract work

    Veracity

    San Francisco, CA
    2 days ago
  •  ...Arcade Office Of The CEO, Chief Of Staff Arcade is building the world's first AI physical product creation platform, where imagination becomes reality. Our platform lets anyone design, purchase, and sell custom, manufacturable products using natural language and generative... 
    Work at office
    Immediate start

    Arcade Studio Inc

    San Francisco, CA
    1 day ago
  • $165k - $225k

     ...Chief Of Staff Career Renew is recruiting for one of its clients a Chief of Staff - this is an onsite role in San Francisco. Salary range: 165-225K USD base plus benefits plus equity. We are building AGI for banking. We're replacing decades-old legacy systems with... 

    Career Renew

    San Francisco, CA
    2 days ago
  • $220k - $345k

     ...Senior Operator, Chief Of Staff To The President The Center for AI Safety (CAIS) is a leading research and advocacy organization focused on mitigating societal-scale risks from AI. We address AI's toughest challenges through technical research, field-building initiatives... 
    Contract work
    Work at office
    Local area
    Shift work

    Center for AI Safety

    San Francisco, CA
    2 days ago
  •  ...Navi is scaling across flight schools, airlines, and the U.S. Air Force simultaneously. The Chief of Staff will be the connective tissue between founders, engineers, pilots, schools, and defense partners, ensuring that nothing slips through the cracks as we scale from... 

    Navi AI

    San Francisco, CA
    3 days ago
  • About Roger Roger is an AI platform that frees home health clinicians from paperwork so they can focus on what matters: delivering life-changing care to our most vulnerable elderly patients in the comfort of their homes. Backed by leading healthcare investors like...
    Flexible hours

    Roger Healthcare

    San Francisco, CA
    2 days ago
  • $110k - $160k

     ...talent at innovative companies. Our team is 100% remote and we work with teams across the United States to help them hire. Chief of Staff Location: San Francisco, CA (On-site) Company Stage of Funding: Seed Stage Office Type: In-person 5 days/week Salary... 
    Work at office
    Remote work
    Visa sponsorship

    Recruiting from Scratch

    San Francisco, CA
    1 day ago
  •  ...About the job Chief of Staff About the Company Our client is building one of America's leading AI-powered financial wellness platforms, helping consumers build, manage, and grow their financial lives through intelligent, AI-driven financial guidance. As... 
    Full time
    Remote work
    Flexible hours

    Cross Border Talents Recruiting Ltd

    San Francisco, CA
    3 days ago
  •  ...Chief Of Staff, Strategic Growth Initiatives Location: West Coast–Based (San Francisco or Seattle preferred) Reports to: Chief Client & Growth Officer Role Purpose: The Chief of Staff serves as the operating backbone of a high-priority, multi-workstream strategic... 

    Talentry LLC

    San Francisco, CA
    2 days ago
  • $130k - $170k

    AI Interpretability Specialist Consumers are using AI models to help them buy things. First AI models were information aggregators: tools people used to search and summarize. Now they're trusted advisors: what people consult before making a decision. Increasingly, they...
    Immediate start
    Shift work

    Unusual

    San Francisco, CA
    3 days ago
  •  ...Anthropic, we are moving with relentless focus to deploy the economic substrate for autonomous agents. About the Role Chief of Staff to the CEO - a high-trust, high-agency role at the center of the company. The CEO architects the product and vision; you architect... 
    Interim role

    Sapiom, Inc

    San Francisco, CA
    2 days ago
  •  ...We are looking for a Chief of Staff to join our team in San Francisco. In this role, you will work directly with the CEO on initiatives across product, marketing, and operations. This is a part-time role, with the potential to transition into a full-time role... 
    Full time
    Part time

    Finvest

    San Francisco, CA
    2 days ago
  • $115k - $150k

     ...Chief Of Staff Kada Recruiting is partnering with a fast-growing, venture-backed AI startup to find a dynamic Chief of Staff to join their hybrid team in San Francisco. This is an exciting opportunity to work directly with the CEO and leadership team at a company that... 
    Work at office
    Remote work

    KADA Inc

    San Francisco, CA
    3 days ago
  • $124k - $222.64k

     ...Job Requisition ID # 26WD98779 Chief of Staff, Fusion Sales Position Overview The Chief of Staff, Fusion Sales serves as a strategic partner and force multiplier to the Vice President of Fusion Sales. This role is responsible for driving operational excellence... 
    For contractors

    Autodesk

    San Francisco, CA
    4 days ago
  • $224k - $280k

     ...make sure cadences and processes are reflective of an ever changing way of working? The Team You’ll Work With You’ll be the Chief of Staff to the Chief Product Officer, Vrushali Paunikar. This is a highly visible and collaborative role that will be core to the... 
    Full time
    Work at office
    Shift work

    Jobleads-US

    San Francisco, CA
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Chief Of Staff. Be the first to apply!