Product Designer/Sr. Product Designer
MatterWorks
About Us Most of the molecules driving human biology are invisible to us. Mass spectrometers already detect metabolites, lipids, and peptides, but the vast majority of those signals never get identified. A typical experiment names a small fraction of its features and discards the rest. We call this biology's dark matter. It’s signal-rich and mechanism-defining, yet almost entirely opaque. Matterworks is building the foundation models that make that dark matter legible. Our Large Spectral Models do for biochemical biology what AlphaFold and ESM did for proteins: turning a library-bound discipline into something predictable and generative, and embedding it at every stage of R&D. Come build the future of biological discovery with us. Position Overview As a Product Designer/Sr. Product Designer at Matterworks, you will shape how scientists interact with Pyxis, our application layer for foundation models of biochemical data. The role spans two design challenges: shipping end-to-end product work in our core web application, and helping us invent the patterns that make our models accessible across emerging surfaces, including our MCP connector and other agentic interfaces. The conventions for how scientists work with AI-native tools in biology don't fully exist yet. You'll help us define them. We're hiring at the Product Designer or Senior Product Designer level. This is a part-time contract role at roughly 20 hours per week. The initial engagement runs 3 months, with potential to extend or convert to full-time as we scale. Key Responsibilities Iterate at high velocity: Produce dozens of design explorations through sketching, Figma, and coded prototypes in tools like Claude and v0. Craft beautiful final designs: Bring final work to a high bar of polish in typography, hierarchy, and interaction. Build reusable components: Turn recurring patterns into components that compose across the web app, MCP, and agentic surfaces. Understand users deeply: Stay close to scientists through user interviews, customer calls, and session replay reviews. Collaborate across the team: Work with PM, engineers, and scientists to align on user needs and tradeoffs. Qualifications We care more about portfolio depth than years of experience. Typical Product Designer candidates have 3+ years; Senior Product Designer candidates have 6+, with significant time in a senior IC role. A portfolio that demonstrates end-to-end ownership of complex product surfaces alongside systems thinking (reusable patterns, components, or design primitives). Please include a portfolio link with your application. Genuine love for the craft of design. You sweat the details because you can't help yourself, study products you admire, and find joy in the work itself. Strong self-direction. You can take a brief, run with it independently, and come back with credible progress without close supervision. Experience designing data-dense interfaces (tables, plots, dashboards). Curiosity about scientific domains. You don't need a biology background, but you should be excited to learn about mass spectrometry, omics, and the workflows of lab scientists. Comfort pairing with engineers through implementation, not just at handoff. Comfort with ambiguity and a bias for shipping. You'd rather get something in front of users in a day and iterate than design in isolation for a week. Fluency in Figma, rapid-prototyping tools (Claude, v0, Cursor, or similar), and clear written communication. Experience designing AI-powered, agentic, or model-driven products is a plus, especially work that spans multiple surfaces or modalities. Working at Matterworks Given the cross-disciplinary and innovative nature of our work, effective collaboration and communication are critical to our progress. We operate in a flexible hybrid model that accommodates both fully remote team members and those who work full-time from our Somerville, MA office. While some positions may require regular in-person presence for hands‑on work or local collaboration, many roles can be performed remotely with team members distributed across various locations. Compensation and Benefits Matterworks offers full‑time employees a competitive base salary, stock options, and benefits (health & dental, vision, long‑ and short‑term disability, life insurance, 401k with company match). Employees enjoy a flexible work & unlimited time away policy, commuter benefits and parking, regular team meals and outings, and company support for continued education/coursework and conference participation. Matterworks, Inc. is an equal opportunity employer. All candidates for employment at Matterworks are considered without regard to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, sexual orientation, or any other category protected by law. #J-18808-Ljbffr
$65 - $75 per hour
...of consumer engagement. Are you ready to redefine the future of user experience on a global scale? We are seeking a visionary Product Designer to join our team and play a pivotal role in shaping intuitive, impactful, and world‑class digital experiences. In this role, you...SeniorWork experience placementWork visaShift work- ...A mission-driven technology company is seeking a Senior Product Designer to join their team in Brookline. This role involves shaping product experiences from initial concepts to implementation, focusing on creating inclusive and empowering designs for women in martial...Senior
$115k - $140k
...EF World Journeys is looking for a Senior Product Designer to enhance the digital experience across its travel brands. You'll work within a cross-functional pod, leading product design from problem framing to shipping. Ideal candidates have 5+ years of design experience...Senior- ...EF Education First is looking for a Senior Product Designer to join our UX team in Cambridge. You will enhance digital experiences across travel brands and lead product design from research through to delivery. The ideal candidate has 5+ years of experience and a passion...SeniorFlexible hours
- ...Matterworks, Inc. in Somerville, MA is looking for a Product Designer/Sr. Product Designer to shape how scientists interact with their application layer for foundation models of biochemical data. This part-time contract position requires proficiency in Figma and rapid-...SeniorContract workPart timeWork at officeRemote workFlexible hours
- ...Senior Product Designer EF Education First is seeking a Senior Product Designer to join our UX team at EF World Journeys, enhancing the digital experience across our travel brands: Go Ahead Tours, Ultimate Break, and Adventures. Please include a cover letter and a...SeniorWork at officeRelocation2 days per week
$120k - $150k
...Java Script Works is seeking a Senior Product Designer based in Massachusetts, Cambridge. You will play a pivotal role in delivering user-focused designs for iOS and Android applications, collaborating closely with team members and clients. Responsibilities include refining...SeniorRemote workFlexible hours- ...Brookline, United States | Posted on 10/23/2025 We are now looking for a Senior Product Designer to join us as a foundational member of the team. You’ll play a key role in shaping how FeMMA looks, feels, and functions — from early product explorations through launch and...Senior
$120k - $150k
...for We are looking for talented, creative and positive team players to join our highly-skilled Cross-Functional Product and Engineering Team to help design new features for our iOS, Android and Apple watch applications and third-party integrations (Garmin, Strava, Coros...SeniorWork at officeRemote workFlexible hours- ...Education First seeks a Senior Product Designer in Cambridge, MA, to lead design within cross-functional pods that enhance user experience across travel brands. This role requires collaboration and design expertise across research, interaction, and visual design, with...Senior
- ...Aquent, based in Cambridge, MA, is seeking a visionary Product Designer to redefine user experiences on a global scale. In this pivotal role, you will collaborate with product and engineering teams to craft impactful digital experiences, championing human-centered design...Senior
- ...Skill is seeking a talented Product Designer to enhance user experiences through innovative design and holistic solutions. You will lead product design from ideation to implementation, collaborate across teams, and ensure adherence to human-centered design principles....SeniorContract work
- ...Klaviyo in Boston, Massachusetts, is seeking a Product Designer to design end-to-end product experiences across their platform. The ideal candidate will simplify complex workflows and design AI-assisted experiences to enhance user interaction. We're looking for someone...Senior
- ...growth PE firm, scaling to about 225 employees and offering its product in over 10 countries. In 2024 General Atlantic, a leading... ...Role Overview We're seeking an experienced Senior Product Designer to shape how users interact with complex geospatial data and wildfire...SeniorTemporary work
$155k - $215k
...A leading health technology company is looking for a Senior Product Designer to join their Growth team in Boston. This role focuses on crafting world-class e-commerce digital experiences that enhance conversion and engagement. The ideal candidate will have extensive experience...Senior- ...STATE STREET CORPORATION is looking for a Senior Product Designer in Boston, MA to expand their wealth service offerings across custody and clearing. You'll work on consumer-focused applications, shaping user experiences and interaction models. The ideal candidate has...Senior
$150k - $175k
...A leading software company is seeking a talented UX designer to join their team in Boston. The role involves creating exceptional designs and prototypes for B2B SaaS products. You'll be working closely with product managers and developers to enhance user experience. The...Senior- ...SLM Education Services LLC is looking for a Senior Product Designer to join their team to expand the new Education Services division. The ideal candidate will focus on strategic user-centered design and collaborate across teams to deliver exceptional digital experiences...SeniorFlexible hours
$155k - $215k
...technology and analytics platform help individuals optimize recovery, training, and overall health. WHOOP is seeking a Senior Product Designer to join the Growth team. You'll focus on crafting world-class digital experiences that drive growth outcomes like acquisition,...SeniorFull timeInternshipWork at officeRelocation- ...Compass is seeking a Senior Product Designer to shape the CRM experience of their Home Platform. This role involves collaborating with Product, Engineering, and Data teams to design scalable workflows for real estate agents. The ideal candidate has over 7 years of experience...Senior
$134.4k - $201.6k
...Klaviyo Inc. is looking for product designers in Boston, Massachusetts to help shape personalized customer experiences. This role emphasizes simplifying complex systems and designing intuitive solutions across the platform. The ideal candidate will have experience in fast...Senior- ...Senior Product Designer This position will have hybrid in-office requirements (2 days per week) if you are located within 50 miles of Portsmouth, NH, Boston, MA, Seattle, WA, or Plano, TX Join the User Experience organization at Liberty Mutual! The UX organization...SeniorWork at officeLocal area2 days per week
$150k - $200k
...Senior Product Designer Boston or NYC Layer Health was founded in 2023 by leading machine learning researchers from MIT and Harvard Medical School. We are building an AI layer that can accurately and scalably synthesize information from medical records, with the...SeniorWork at officeImmediate startFlexible hours2 days per week- ...A dynamic technology company in Boston is seeking a talented Product Designer to join the product squad. This role emphasizes end-to-end product design, user research, and collaboration with cross-functional teams. Ideal candidates will have 5+ years of experience in...SeniorFlexible hours
$125k - $140k
...A leading health-tech firm is looking for a Senior Product Designer to transform the user experience on their AI-powered platform. You will be responsible for designing enterprise CRM and data visualization solutions that directly impact drug development processes. With...SeniorRemote work- ...Senior Product Designer Clio is the global leader in legal AI technology, empowering legal professionals and law firms of every size to work smarter, faster, and more securely. We are transforming the legal experience for all by bettering the lives of legal professionals...SeniorWork at officeLocal areaImmediate startFlexible hours
- ...Senior Product Designer Global restaurant brands run their operation on the Crunchtime platform. Delivering a consistent guest experience across every location and managing food and labor costs are at the core of how Crunchtime's software is used today in over 150,...SeniorFlexible hours
- ...Dormont Manufacturing Co in Boston is seeking a skilled Product Designer to take ownership of product design for enterprise integrations. You will collaborate closely with a Senior Product Manager and engineers, ensuring designs meet user needs and facilitate complex...Senior
$108.4k - $135.5k
...they need to grow online. We’re energized by new challenges and new possibilities-and we’re just getting started! The Senior Product Designer designs industry-leading user experiences that achieve business objectives and successful customer outcomes. They apply design...SeniorFull timeFor contractorsWork at officeRemote work$102.5k - $135k
...Senior Product Designer (PLM Solutions Design) Boston, MA (Hybrid) Our world is transforming, and PTC is leading the way. Our software brings the physical and digital worlds together, enabling companies to improve operations, create better products, and empower...SeniorWork at officeLocal areaImmediate startFlexible hours
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Product Designer/Sr. Product Designer. Be the first to apply!
- senior brand designer Somerville, MA
- senior business analyst contract Somerville, MA
- senior database analyst Somerville, MA
- legal senior counsel family office Somerville, MA
- senior aws cloud engineer Somerville, MA
- senior financial analyst remote Somerville, MA
- senior vmware engineer Somerville, MA
- senior consulting engineer Somerville, MA
- senior human factors engineer Somerville, MA
- senior developer Somerville, MA

