Principal Scientist, Data Science - AI & Generative AI Systems - R&D DDSAI - Therapeutics Development & Supply (TDS)

Johnson & Johnson seeks a Principal Scientist in Data Science to design, build, and deploy AI and generative AI systems that accelerate workflows in therapeutics development and supply. The role involves developing LLM applications, agentic workflows, and AI-driven automation solutions across product development, manufacturing, clinical supply chain, and quality teams.

Responsibilities

• Design, build, test, and deploy AI solutions for documentation, knowledge retrieval, evidence synthesis, and decision support in therapeutics development ecosystem
• Build agentic AI workflows that coordinate models, tools, data, and human review across multi-step scientific and supply chain processes
• Establish evaluation frameworks for LLM systems including rubrics, traceability, robustness, uncertainty, and usability
• Partner with regulatory, quality, CMC, and scientific stakeholders to define use cases, validate outputs, and drive adoption
• Collaborate with DDSAI AI/ML teams on infrastructure, architecture, evaluation, and reusable components

Requirements

• Bachelor's degree in Engineering, Data Science, Life Sciences, Computer Science, or related field; advanced degree preferred
• 3–5+ years hands-on experience building and deploying AI, NLP, or generative AI solutions including large language models
• Experience in pharmaceutical product development, specifically Chemistry, Manufacturing and Controls (CMC)
• Strong proficiency in Python
• Strong communication skills to explain technical topics to non-technical stakeholders
• Experience with open-source agentic frameworks (e.g., LangGraph, DSPy, mem0)
• Experience with retrieval-augmented generation, embeddings, vector databases, and model evaluation