Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Backend Typescript Developer

Full-time

Sequencing

Role Description

As a Senior Backend TypeScript Engineer, you build and maintain the high-performance backend services that power our core personalized health experiences. You work side by side with other senior engineers to build and grow scalable infrastructure APIs and event-driven services.

  • Design, build, and maintain performant backend services in TypeScript that power our core personalized experiences.
  • Build and grow scalable infrastructure APIs and event-driven services that deliver data-driven features to users.
  • Support and optimize production-ready backend systems so they stay fast and dependable under load.
  • Integrate and manage services such as PostgreSQL, MySQL, AWS SQS, and Centrifugo in the backend.
  • Make systems reliable, secure, and observable so people can trust their DNA data is safe.
  • Own and drive end-to-end feature development with a strong eye on user experience.
  • Write clean, reliable code with performance and maintainability in mind from the start.
  • Champion clean code, technical excellence, and continuous improvement across the team.
  • Debug, test, and performance tune across services to catch problems before users feel them.
  • Maintain, modernize, and migrate legacy code so older systems keep up with new demand.
  • Take ownership of complex problems and drive them to a clear working solution.

Qualifications

  • 5+ years of backend development experience.
  • Expert with TypeScript and comfortable owning production backend services.
  • Experience with functional programming.
  • Deep hands-on experience with PostgreSQL, MySQL, and service-based architectures.
  • Strong debugging, testing, and performance tuning skills.
  • Able to work independently while collaborating closely with key teammates.
  • Customer-driven with a passion for building systems that deliver exceptional experiences.
  • Nice to have: familiarity with genomics, health data, or personalization systems; startup or fast-paced environments; or Rust.

Benefits

  • Comprehensive medical, dental, and vision insurance coverage.
  • 401(k) with company matching.
  • Paid time off (PTO).
  • Paid volunteer time off.
  • Fully remote work with home office stipend.
  • Parental bonding leave.
  • Clinical-grade whole genome sequencing for you and your family (private and confidential).

Company Description

Sequencing is building the interface between humanity and its DNA. Using clinical-grade whole genome sequencing, AI, and a rapidly expanding ecosystem of genomic applications, we help people better understand themselves, their health, and their future through their DNA. Our mission is to transform the human genome into a lifelong source of personalized guidance and build the trusted home for every genome on Earth.

As the world’s largest direct-to-consumer whole genome sequencing platform, Sequencing is helping define the future of AI-powered personalized health. We’re a profitable, venture-backed, fully remote company building category-defining products that help people better understand themselves through their DNA.

Vacancy posted 16 hours ago
Similar jobs that could be interesting for youBased on the Senior Backend Typescript Developer in Remote vacancy
  • $100k - $150k

     ...Senior Backend Developer - Remote Bright Vision Technologies is a technology consulting and software development company delivering cloud, AI, data, and enterprise solutions across the United States. This is a fantastic opportunity to join an established and well... 
    Senior
    Full time
    H1b
    Local area
    Immediate start
    Remote work
    Visa sponsorship

    Bright Vision Technologies

    United States
    1 day ago
  • Role Description As our Senior Software Developer, GenAI, you’ll contribute to building and scaling...  ...maintain product features and supporting backend components, including services,...  ...backend focus. ~4+ years working with Typescript / Node.js / C#. ~Advanced... 
    Senior
    Full time
    Remote work

    Varicent

    Remote
    6 days ago
  •  ...the role This is a full-time remote role for a Senior Backend Software Engineer at Makai. This person will be responsible...  .... The ideal candidate will be able to Develop new features across our Node.js/TypeScript backend services Optimize applications for... 
    Senior
    Remote job
    Full time
    Local area
    Flexible hours

    Makai Labs

    New York, NY
    16 hours ago
  • Role Description Como Senior Backend Spark Developer, serás una pieza clave en el diseño, desarrollo y optimización de soluciones de procesamiento de datos. Tendrás la responsabilidad de liderar decisiones técnicas, contribuir activamente al diseño de la arquitectura y... 
    Senior
    Full time

    Zemsania

    Remote
    16 hours ago
  • Role Description Garantir a excelência técnica na construção das soluções, traduzindo requisitos de negócio em código robusto, escalável e sustentável, seguindo os padrões arquiteturais definidos pelo time. Atuar como referência técnica no dia a dia de desenvolvimento, ...
    Senior
    Full time

    Sensedia

    Remote
    5 days ago
  •  ...produktiver zu machen. Um weiter zu wachsen, suchen wir vielseitige TypeScript-Entwickler:innen, die Lust haben, früh Verantwortung zu ü...  ...-Framework (React, Solid, Vue, Astro) ~Erfahrung im Backend-Bereich, z. B. mit fastify, NestJS oder vergleichbaren Frameworks... 
    Senior
    Full time
    Remote work
    Flexible hours

    dreifach.ai

    Remote
    3 days ago
  • Role Description We are looking for a passionate software developer to join our engineering team. You will collaborate with product managers...  ...web applications in Java and/or Kotlin ~Experience with Typescript and the React ecosystem are a definitive plus ~Degree in... 
    Senior
    Full time
    Remote work
    Work from home

    Tempo

    Remote
    1 day ago
  • Role Description We're looking for an experienced Senior Symfony Backend Developer to own and evolve our API and domain layer. You'll maintain and optimize an existing, complex codebase, ship new features and integrations, and help raise the bar on architecture, testing... 
    Senior
    Contract work
    Work at office
    Local area
    Remote work

    Elegant Networks PTE. LTD.

    Remote
    2 days ago
  • Role Description You will be responsible for developing backend services for the StellarTech Platform, building new functionality from scratch...  ..., and stability of the platform. The role is ideal for a senior backend engineer who enjoys solving complex technical challenges... 
    Senior
    Full time
    Flexible hours

    Stellar Tech

    Remote
    3 days ago
  • $200k - $270k

    Role Description As a Senior Backend Developer for the Trust & Safety Platform at Bluesky, you’ll be responsible for building and maintaining the infrastructure that powers moderation, anti-spam, and user safety. You’ll work closely with our internal operations and product... 
    Senior
    Full time
    Remote work

    Bluesky

    Remote
    16 hours ago
  • Role Description Join us as a Senior Backend Developer on our mission to turn payments into possibilities! We are looking for a Senior Backend Engineer with strong experience designing, building, and operating complex distributed systems. You will join a high-performance... 
    Senior
    Full time
    Contract work

    CellPoint Digital

    Remote
    5 days ago
  • Role Description Would you like to build the backend behind maritime geospatial analytics, from wherever you already live? This role sits with an international scientific and technology centre working on maritime research. The work is remote in full, on a cloud based collaboration... 
    Senior
    Full time
    Remote work

    WLG

    Remote
    3 days ago
  • Role Description We are looking for a Senior Backend Developer to join our rapidly growing team. This is an amazing opportunity to join Sumsub and make an immediate and real impact on the future of our product. Our Stack: ~Main language: Java 17 ~Java Framework:... 
    Senior
    Full time
    Immediate start
    Remote work
    Worldwide

    Sumsub

    Remote
    2 days ago
  •  ...expanding our team and are looking for a skilled, goal-oriented backend developer to help us grow. You'll work on services, APIs, databases,...  ...the impact of your work directly Fast career progression: a senior-heavy team and a high volume of real problems means you grow... 
    Senior
    Remote work

    GrabJobs

    Indianapolis, IN
    2 days ago
  • Role Description ~Push production AI agents into the platform's most complex flows. Build the MCP servers that orchestrate them: tool layer, context handling, model routing through OpenRouter. ~Build the integration layer that powers the platform and the AI agents on...
    Senior
    Full time

    TEAM International Services, Inc.

    Remote
    16 hours ago
  • $75k - $96k

    Role Description The Senior Back-End Developer is responsible for building and maintaining the server-side operations and functionality of cloud-based solutions supporting Bible translation and publishing workflows. This includes developing and maintaining the database... 
    Senior
    Full time
    Work experience placement
    Worldwide

    Wycliffe Bible Translators USA

    Remote
    4 days ago
  •  ...Description En este puesto, te incorporarás al área de desarrollo backend para integrarte de forma rápida a un equipo dinámico con un...  ...de casos de prueba técnicos. Qualifications ~Experiencia senior comprobable (3+ años) en el rol de Desarrollador Backend utilizando... 
    Senior
    Full time

    Coderio

    Remote
    16 hours ago
  •  ...To support the development of intelligent engineering solutions, the full-time Senior Backend Developer will design and build backend services for the Operator team, focusing on scalable retrieval systems and AI-powered experiences while working remotely from anywhere... 
    Senior
    Full time
    Remote work

    Virtual Vocations Inc

    United States
    4 days ago
  • $10,000 per month

    Role Description We are looking for an experienced Senior Backend/API Developer to architect, develop, and maintain the backend infrastructure that powers the Ardhanarishvara platform. The successful candidate will design scalable APIs, secure integration layers, authentication... 
    Senior
    Full time
    Contract work
    Remote work
    Worldwide

    CX25WW

    Remote
    16 hours ago
  • $110k

     ...Overview Senior Backend Developer role at Ryder System, Inc. The position develops, builds, and maintains scalable back-end solutions in a multi...  ...and development tools/frameworks (e.g., Ruby on Rails, TypeScript, or other object-oriented languages) and strong knowledge... 
    Senior
    Full time

    Ryder

    Honolulu, HI
    23 hours ago
  • $6,250 - $9,583 per month

     ...hands to find your next job opportunity. Job Title: Remote Senior Backend Developer (100% Work From Home) Location: Remote from Latin...  ..., Skills and Key Competencies: Backend: Node.js, TypeScript, REST API design, and queue-based architectures (SQS, event... 
    Senior
    Full time
    For contractors
    Immediate start
    Remote work
    Work from home
    Monday to Friday

    HireLATAM

    United States
    1 day ago
  • $125k - $165k

    Role Description Fullscript is looking for an experienced Senior Backend Engineer to join the infrastructure team responsible for the long-term health, scalability, and developer experience of Fullscript’s core application. Our team enables fast, reliable product development... 
    Senior
    Full time
    Flexible hours

    Fullscript

    Remote
    16 hours ago
  • Role Description Buscamos un Backend Senior con experiencia sólida en Java moderno (Spring Boot + WebFlux) y conocimiento prioritario de integración con Simetrik para la conciliación y control financiero de productos digitales. Trabajarás sobre AWS, construyendo soluciones... 
    Senior
    Full time
    Remote work

    Keppri

    Remote
    6 days ago
  •  ...amazing things for our clients. We are looking for mostly a backend developer, but if you are fullstack that works too. We’re looking for someone...  ...written and spoken English ~Must have experience as a Senior Ruby on Rails developer ~Proven work experience in... 
    Senior
    Contract work
    Work experience placement
    Remote work

    Maxiom Technology

    Remote
    5 days ago
  • Role Description We're looking for a proactive, technically strong Senior Backend Python Developer to join our team. You'll work on a strategic project for one of our banking clients, designing and maintaining the microservices that power our AI platform — including model... 
    Senior
    Full time
    Remote work

    Muttdata

    Remote
    16 hours ago
  •  ...Familiarity with Agile software development methodologies. ~Proficiency with relational databases. ~Experience in building frontend/backend applications at scale. ~Proficiency in the English language. Requirements ~Knowledge of Python web frameworks (Flask or... 
    Senior
    Full time
    Flexible hours

    3Pillar

    Remote
    16 hours ago
  • $120k - $140k

     ...fixes, implement feature enhancements, and develop REST APIs. ~Focus on production reliability...  ...complex systems. ~Collaborate with senior architects and a 10-person team. Qualifications ~8+ years of backend development experience in the .NET ecosystem... 
    Senior
    Full time
    Flexible hours

    Billee.AI

    Remote
    16 hours ago
  • $100k - $150k

    Role Description We are seeking an experienced Senior Backend Developer – Python to design, build, and continuously enhance complex enterprise-grade applications, data-intensive services, and automation platforms. This is a hands-on engineering role focused on delivering... 
    Senior
    Full time
    Immediate start

    Bright Vision Technologies

    Remote
    16 hours ago
  • $70 per hour

    Role Description We are looking for a talented and experienced backend software engineer. As a backend software engineer, you will design, develop, and test scalable server-side applications and services using modern technologies, working directly with clients to understand... 
    Senior
    Hourly pay
    Long term contract
    Full time
    Contract work
    H1b
    Remote work

    Transform Labs

    Remote
    5 days ago
  • Role Description We are seeking a seasoned Senior Python Backend Developer: Team Lead to lead backend development, integrate computer vision capabilities into our architecture, and ensure our cloud systems are high-performing, reliable, and secure. Key Responsibilities... 
    Senior
    Full time
    Remote work
    Flexible hours

    Nacre Capital

    Remote
    4 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Backend Typescript Developer. Be the first to apply!