USM Business Strategy & Operations Senior Manager (Field)

The Position

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love.

At USM, we play a pivotal role in driving Genentech's mission to expand patient access to life-changing therapies. Our focus is on empowering healthcare stakeholders with the scientific evidence they need to make informed treatment decisions. By fostering deep collaborations across the dynamic healthcare ecosystem, we are committed to delivering better outcomes for patients while ensuring care remains accessible and affordable for all.

The Opportunity

The S&O Senior Manager orchestrates US Medical operations and capabilities. Reporting to the Head of Field Medical Excellence & Business Enablement, this role drives infrastructure and technology standards to ensure organizational excellence.

As a strategic execution partner, the manager translates the USM vision into field execution and operational discipline. The goal is to establish Field Medical as the premier scientific partner through a holistic customer experience.

Key Responsibilities

Drive Strategic Planning & Execution (The Enabler)

• Translate USM and Field Medical objectives into clear execution roadmaps and manage high-priority workstreams to ensure delivery and alignment.

Ensure Operational Rhythm & Effectiveness (The Orchestrator)

• Own the "Rhythm of USM" by embedding strategy into day-to-day execution, optimizing functional processes, and managing system evolution to ensure measurable outcomes and compliance.

Serve as a Strategic Thought Partner & Confidant

• Act as a trusted advisor by offering the "pulse" of USM, providing candid guidance, pressure-testing assumptions, and driving decisions through operational reality-checks.

Manage Cross-Functional Alignment (The Integrator)

• Serve as the strategic integrator, aligning work across functions (USM, DDA, Legal, Compliance, etc.), removing barriers, and acting as the communication conduit to ensure compliance and organizational transparency.

Who You Are

Qualifications & Experience

• Education: Bachelor’s degree.

• Professional Experience: Minimum of 5 years of work experience, including 3+ years in the pharmaceutical/biotech/healthcare industry or management consulting.

• Advisory Experience: Prior experience within a consulting firm or similarly fast-paced, client-focused environment, with demonstrated ability to manage complex priorities, provide strategic support, and operate with a high degree of professionalism and discretion.

• Execution Management: Proven track record in an operational or "pull-through" role, overseeing the maintenance of scalable capabilities or technology platforms.

• Fiscal Acumen: Proven experience managing departmental or project budgets, including forecasting and resource mapping.

• Technical Proficiency: Experience with project management tools and an understanding of AI/Machine Learning applications.

Preferred Experience

• MBA or related graduate-level/advanced degree.

• Launch excellence within the pharmaceutical or biotech industry experience, including cross-functional operational support of pre-launch through commercialization activities.

• 3+ years of experience in clinical development with strong skills in clinical trial data analysis and RWD.

• Certifications such as Six Sigma, PMP, or similar.

• Experience with Agile methodologies and a proven ability to embed products into existing workflows for impactful outcomes.

Location and Travel Requirements

• The role is field-based in either the Northeast and Southern regions, or if based in another region willing to work hours that align with EST working hours. There would be a minimum of 30% of the time expected to be spent in the office in South San Francisco, CA, or traveling to locations designated by the Business.

• This role will be based in the Field

• Preferred States of Residence

• AL, GA, FL, AR, LA, MS, KS, MO, KY, TN, VA, MI, OH, NC, SC, IN, IL, TX, OK, AZ, NM, PA, MD, NY, PA, WV, MA, CT, ME, RI, VT, CA

The expected salary range for this position based on the primary location of South San Francisco, CA is $118,300.00 - 219,700.00. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits (

Relocation benefits are not available for this job posting.

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants ( .