Senior Translational PK/PD Lead — Model-Driven Drug Discovery
MSD
MSD in South San Francisco, CA seeks a Translational PK/PD Associate Director to lead modeling for biologics and protein therapeutics. You will independently design analyses guiding drug discovery strategy and dose prediction in cross-functional teams. Work with in vitro and in vivo data to build PKPD/PBPK/QSP platforms, support forward translation, and collaborate to shape translational strategy across programs. Hybrid work arrangement offered. #J-18808-Ljbffr MSD
- Merck & Co., Inc. in the United States seeks a Translational PK/PD Scientific Associate Director to lead modeling efforts in the Translational PK/PD organization... ...and peptides. The role emphasizes model-informed drug discovery and cross-functional collaboration. The...Senior
- Merck & Co., Inc. is seeking a Translational PK/PD Associate Director to... ...execute PK/PD analyses guiding drug discovery for biologics, proteins,... ...This role combines expert modeling with cross-functional leadership... ...(PKPD, PBPK, QSP), and lead junior colleagues while collaborating...Suggested
$129k - $203.1k
...seeking a curious and collaborative Senior Scientist for our growing Translational PK/PD organization. The Translational... ...is a skilled mathematical modeler and scientist who designs and executes... ..., with supervision, guiding drug discovery strategy with a focus on biologics...SeniorFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$210k - $250k
Lead, Oncology and Translational Medicine, is a key scientific leader and integral member of the drug discovery team accountable for all translational research related work enabling... ...discovery biology including oncology models and PK/PD, ASME and efficacy models including...Suggested- ...strategy and oversee non-clinical ADME/PK studies across discovery and development. You will serve on multidisciplinary project teams and translate nonclinical data into human PK and... ...strong communication skills to inform senior stakeholders and regulatory discussions...Senior
- ...for small molecule projects from discovery through development. The role leads ADME/PK studies, integrates DMPK data... ...and communicates complex data to senior stakeholders. The position... ...project leader, with hands-on PK/PD or PBPK modeling preferred. Domestic relocation...SeniorRelocation
- ...The Quantitative, Translational ADME Sciences (... ...support in vivo PK, TK, and PK/PD studies as well as... ...antibody, antibody drug conjugates,... ...techniques. Act as a lead scientist in his/... ...motivated, self-driven and results-oriented... ...in drug discovery/development is preferred...SeniorTemporary work
- ...experienced Sr. Director of Clinical Pharmacology to lead the department’s technical and operational... ...with internal and external teams to advance drug programs in infectious diseases and oncology. The role requires deep PK/PD expertise, leadership experience, and a track...Senior
- NewLimit is seeking a Senior/Principal Scientist with deep expertise in molecular biology and translational biomarker assay development to lead PD biomarker assays that characterize the biological... ...PD biomarker strategy from discovery through fit-for-purpose qualification...Senior
$194.1k - $305.6k
...collaborative Senior Principal Scientist... ...across drug conjugate discovery and development... ...discovery biology, translational sciences,... ...to enable data-driven decision making... ..., ADME, PK/PD, bioanalysis,... ...decisions. Lead the development... ...Familiarity with model-informed drug...SeniorFull timeContract workFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work- AbbVie is seeking a senior Clinical Pharmacology leader to conceive, execute, and manage multi-disciplinary pharmacology development plans that meet commercial and regulatory goals. The role leads PK/PD strategy, proposes study plans, and collaborates with internal teams...Senior
$202.8k - $376.6k
...sciences are transforming drug discovery and development. Roche... ...novel computational models to drive impact.... ...OpportunityThe AI Biology & Translation (AIBT) department... ...exceptional scientist to lead a research program focused... ...AI for biology.As a Senior Principal Scientist,...SeniorFull timeLocal areaWorldwideRelocation package$147.8k - $274.4k
...sciences are transforming drug discovery and development. Roche... ...novel computational models to drive impact.... ...motivated and collaborative Senior/Principal Machine... ...Department of AI for Biology & Translation (AIBT) in Genentech... ...is expected to lead high profile projects...SeniorFull timeLocal areaWorldwide- ...seeking a highly motivated scientist to lead pharmacology efforts within the CVRM Translational Biology group. The role focuses on driving drug discovery and mechanistic studies, coordinating... ...expertise, including cardiovascular models and phenotyping. #J-18808-Ljbffr...Senior
$224k - $299k
..., advanced disease modeling, and computational... ...is revolutionizing drug discovery. insitro is harnessing... ...a Director (or Senior Director) of Translational Medicine and Diagnostics... ...patients' lives by leading translational... ...drives objective, data-driven, and timely go/no-...SeniorWork at officeHome officeFlexible hours3 days per week$177k - $235k
...advanced technologies and model systems to increase... ...that enable people to lead longer and healthier... ...commitment to curiosity-driven discovery science, and, with... ...partners, its vibrant drug-development pipeline,... ...technical expert, you will translate complex in silico...Senior- Xaira Therapeutics is seeking a lab-based Senior Scientist in Inflammation and Immunology to join our Biology & Pharmacology department... ...strategy. You will design and perform preclinical studies, translate findings into actionable insights, and collaborate across cross...Senior
- AbbVie is seeking a senior Clinical Pharmacology Scientist to conceive and execute innovative PK/PD research supporting global clinical programs. You will lead PK strategies, evaluate regulatory advances, and integrate this knowledge into development plans. The role requires...Senior
$259.5k - $380.6k
...unite caring with discovery to help make life... ...doing. If you’re driven by purpose and... ...Build the Future of Drug Discovery in the... ...and frontier AI models trained on Lilly... ...’ll Be DoingAs a Senior AI Science Lead, you will set scientific... ...the ability to translate scientific...SeniorRemote workFlexible hours2 days per week- Genentech, a member of the Roche group, seeks a PhD-level Senior Scientist to advance translational PBPK modeling for small molecule drug discovery and development. The role focuses on physiologically-based pharmacokinetic analyses and cross-functional collaboration in...SeniorRelocation
- ...Research | AI Development (BRAID) within AI Biology & Translation. We seek a Scientist/Senior Scientist with strong computational and data-science foundations... ...into biological and clinical impact. You will define modeling applications for trial decision processes and partner...Senior
- Merck is seeking a Senior Director to lead Bioanalytical sciences within the PDMB organization in South San Francisco. The role focuses... ...bioanalytical leaders and scientists, partner with discovery, translational, and clinical teams, and drive modernization and automation...Senior
- ...seeking an experienced Sr. Director of Clinical Pharmacology to lead the department across preclinical and clinical programs in infectious... ...with at least 3 days in office weekly. You will oversee PK/PD operations, develop regulatory strategies, and guide cross‑functional...SeniorWork at office
- Alector seeks an Associate Director, Bioanalytical Sciences to provide strategic and hands-on leadership across nonclinical and clinical programs at its South San Francisco headquarters. The role combines portfolio-level bioanalytical strategy with direct assay development...Senior
- Mercor is partnering with a leading AI research lab to enhance AI-driven prior authorisation workflows for medical services. We are seeking experienced Prior Authorisation Managers with clinical expertise to train AI systems on medical-necessity criteria and payer review...Senior
- Verily Health is seeking a Senior UX Accessibility Lead to embed within our UX organization to shape inclusive, accessible precision health experiences across web, mobile, and AI-native products. Reporting into UX and partnering closely with Engineering, Product, and AI...Senior
- Rigel Pharmaceuticals Inc. is seeking a senior leader to integrate translational medicine, clinical pharmacology, and biomarker strategy across its portfolio. This executive will shape dose, schedule, patient selection, and go/no-go decisions, reporting to the Chief Medical...Senior
$124.3k - $230.9k
The PositionThe Drug Metabolism and Pharmacokinetics... ...to enabling the discovery, development and... ...to optimize leads, select clinical... ...seeking a Ph.D. level Senior Scientist who is... ...cutting edge translational modeling approaches to support... ...Simcyp, GastroPlus, or PK-Sim.You...SeniorFull timeLocal areaRelocation$155k - $200k
...machine learning models to unravel the biology... ...is seeking a Senior/Principal... ...molecular biology and translational biomarker assay development... ...role, you will lead the discovery, development, and... ...pharmacodynamic (PD) biomarker assays... ...development of drugs across multiple...Senior- MSD in South San Francisco seeks an experienced chemist to lead discovery chemistry efforts, designing and synthesizing drug candidates and probes to advance lead optimization. You will mentor staff, analyze complex data, and publish findings while expanding external scientific...Senior
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