Translational PK/PD Leader - Biologics & PBPK
MSD Malaysia
Merck & Co., Inc. is seeking a Translational PK/PD Associate Director to independently design and execute PK/PD analyses guiding drug discovery for biologics, proteins, and peptides. This role combines expert modeling with cross-functional leadership to shape dose predictions and translational strategies. The candidate will integrate diverse data, develop mechanistic modeling platforms (PKPD, PBPK, QSP), and lead junior colleagues while collaborating across PDMB and broader discovery teams. #J-18808-Ljbffr MSD Malaysia
- Merck & Co., Inc. in the United States seeks a Translational PK/PD Scientific Associate Director to lead modeling efforts in the Translational PK/PD organization, focusing on biologics, proteins, and peptides. The role emphasizes model-informed drug discovery and cross-...Suggested
- MSD in South San Francisco, CA seeks a Translational PK/PD Associate Director to lead modeling for biologics and protein therapeutics. You will independently design analyses... ...with in vitro and in vivo data to build PKPD/PBPK/QSP platforms, support forward translation, and...Suggested
$210k - $250k
Lead, Oncology and Translational Medicine, is a key scientific leader and integral member of the drug discovery team accountable... ...person works closely with the biology leads, and communicates regularly... ...including oncology models and PK/PD, ASME and efficacy models including...Suggested- ...Inc. is seeking a Discovery Bioanalytical Leader to lead a team of scientists and drive in-... ...binding assay efforts supporting discovery PK/ADA studies. The role combines hands-on... ...approaches, and collaborate with Discovery Biology, Pharmacology, Toxicology, and CMC teams to...Suggested
- JLSa2 is seeking a Discovery Bioanalytical Leader to guide a small team in South San... ...You will shape bioanalytical strategies for PK and ADA studies, and oversee LC-MS/MS and... ...strategic oversight, collaborating with multiple biology and CMC teams to accelerate decision-...Suggested
- Genentech is seeking a highly motivated leader to drive DMPK strategy for small molecule... ...through development. The role leads ADME/PK studies, integrates DMPK data into decision... ...a DMPK project leader, with hands-on PK/PD or PBPK modeling preferred. Domestic relocation may...Relocation
- ...residents and fellows. We welcome investigators from stem cell biology, regenerative medicine, genome engineering, neurobiology, genetics, cell and molecular biology, and AI, to study basic and translational aspects of the visual system in a thriving Bay Area #J-18808-...
- insitro is seeking a Director (or Senior Director) of Translational Medicine and Diagnostics to lead translational medicine across neurology, metabolism, and ophthalmology. You will shape strategy from IND/CTA through clinical proof-of-concept and collaborate with Preclinical...3 days per week
- ...quantitative pharmacology efforts across development programs. You will shape PK/PD, population PK, PBPK, and model-based decision making, coordinating with Regulatory Affairs, Translational Sciences, Biostatistics, and external partners. The role emphasizes strategy development...
- Genentech in South San Francisco, CA is seeking a highly motivated scientist to lead pharmacology efforts within the CVRM Translational Biology group. The role focuses on driving drug discovery and mechanistic studies, coordinating multidisciplinary teams to advance candidates...
- Rigel Pharmaceuticals Inc. is seeking a senior leader to integrate translational medicine, clinical pharmacology, and biomarker strategy across its portfolio. This executive will shape dose, schedule, patient selection, and go/no-go decisions, reporting to the Chief Medical...
- Genentech is seeking a highly motivated DMPK leader to drive strategy and oversee non-clinical ADME/PK studies across discovery and development. You will serve on multidisciplinary project teams and translate nonclinical data into human PK and dose predictions. The role...
- ...integrated strategies across programs, from early proof-of-concept to IND-enabling activities. The role emphasizes in vivo pharmacology, translational readouts, and collaboration with CROs to ensure cohesive nonclinical development of the PRINT platform. The ideal candidate has...
$190k - $250k
...diseases. The Discovery Bioanalytical Leader, which reports into the Head of DMPK,... ...discovery research of peptide biologic therapeutics. This role is responsible... ...generation of robust pharmacokinetic (PK), in vivo nonclinical PK/PD, anti-drug antibody (ADA), and related...- Scorpion Therapeutics in South San Francisco, CA seeks a senior leader in pharmacometrics to drive model-based decision making across translational PK/PD, QSP, and regulatory strategy. You will develop and apply quantitative frameworks and collaborate with discovery, development...
- Socket.dev is seeking a Discovery Bioanalytical Leader to guide in-house LC-MS/MS and ligand binding assays for PK/ADA studies, while mentoring a small team of bioanalytical... ...activities. You will partner with Discovery Biology, Pharmacology, Toxicology, and CMC to design fit...
$197.7k - $367.1k
...operates at an enterprise level, capable of translating complex product strategies into... ...and strategic insight. You are a natural leader in matrix environments, comfortable with... ...and/or line extensions; exposure across biologic, synthetic molecule and device supply chains...Work experience placementLocal area$200k - $230k
...Description:Allogene is seeking a Product Quality Leader (PQL) to oversee Allogene’s CAR T... ...or at CMO.Demonstrates the ability to translate complex process knowledge and... ...Practical knowledge and solid understanding of biological drug development process from early development...Full timeContract workWork experience placementWork at officeLocal area- Genentech is seeking a DMPK leader to drive strategy for small molecule programs across discovery and development. You will design and oversee in vitro and in vivo ADME/PK studies, translate findings into human PK/dose predictions and guide project teams with senior stakeholders...Relocation
$145.46k - $207.8k
.... Reporting to the Head of Innate Immunity & Cancer Cell Death Biology, the People Manager will balance project support with people management... ...Experience leading antibody and/or ADC projects as a project leader. Prior people management or team leadership experience. Solid...Flexible hoursNight shiftEarly shift- ...experience in antibody characterization and a Ph.D. in a related field. Responsibilities include developing assessment packages for biologic candidates and mentoring a scientific team. Join us if you are analytical, experienced, and eager to contribute to therapeutic...
$158.2k - $293.8k
...ability to influence and negotiate effective solutions within PDQ, PD, and/or industry through leading change and driving for results;... ...new and emerging compliance information or trends and translate into impact for PDQProven record of working in a global, multicultural...Full timeLocal areaRelocation package- ...Regional Business Director to lead a high-performing team driving the launch and commercialization of biosimilars and innovative biologic therapies. The role reports to the National Project Director and oversees Key Account Managers across a defined geography. The ideal...
$207.1k - $384.5k
...functional delivery in alignment with broader PD-DSA and Roche strategies.You align... ...leadership for DEPCS within Ophthalmology, translating enterprise and functional priorities into... ...build strong relationships with TA-aligned leaders across PDD to support seamless...Full timeLocal areaRelocation package- AbbVie seeks an accomplished Clinical Pharmacology leader to conceive, execute and manage PK/PD development plans across multiple programs, ensuring regulatory readiness and business goals. This role drives strategy, data interpretation, and collaboration with internal...
$247k
...Early Development (gRED) team is excited to add a Project Team Leader (PTL) to lead projects and portfolio related activities across... ...and Manufacturing.Utilize his/her deep understanding of disease biology and global drug development to effectively lead Project Teams and...Full timeLocal areaRelocation package$153.69k - $187.85k
...community visions to life. BKF is hiring a Bay Area Regional Biology Lead to support our growing biological resources and regulatory... ...forward‑thinking, results‑oriented team player and resourceful leader. Ability to handle critical conversations with internal staff,...Work at officeLocal areaRemote workFlexible hours- Astellas is seeking a Biological Safety Manager (EHS) based in South San Francisco, CA, to oversee the Biosafety Program and lead the IBC, IACUC, and Occupational Health activities. The role involves risk assessments, regulatory compliance, and program development to enhance...
- ...brands and cross-functional teams in the US with compliant multilingual content at scale. The role emphasizes building AI-enabled translation workflows, managing linguistic assets, and partnering with Brand Marketing, Medical Affairs, and external studios to ensure...
- ...ideal candidate will possess over 5 years of relevant experience and exceptional communication skills, demonstrating the ability to translate technical capabilities into clear business value. The position offers competitive compensation, comprehensive health coverage, and...
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