Sr. Technical Program Manager, AI Security
$145.9k - $234.2kModerna
Senior Technical Program Manager (TPM)
Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management of AI-readiness initiatives at Moderna globally. We're looking for someone with a high level of integrity and personal accountability, strong interpersonal skills, and infrastructure technology domain expertise.
Here's What You'll Do
- Program Management – take a structured, data-driven, and risk-based approach to program scoping, execution, and reporting
- Kick off and successfully manage multiple, simultaneous, complex, high visibility workstreams with full ownership, effective collaboration, and good process
- Build processes, templates, and structure, or leverage existing ones as appropriate
- Manage vendors, schedule, scope, and cost
- Measure program success (or lack thereof) and risks using data and facts
- Provide balanced risk remediation strategies and recommendations and drive risk mitigation
- Develop and maintain close stakeholder relationships and build influence to drive the appropriate outcomes across Moderna
- Provide clear, accurate, consistent, and timely communications
- Advance good infrastructure and security practices and culture
- Partner Collaboration - work with Cybersecurity, Builder Tools & Platforms, Infrastructure, Identity & Endpoint Engineering, GRC, AI Engineering, Data, Enablement/L&D, software engineering, and business stakeholders to manage and drive improvement projects in a structured and predictable manner
- Manage multiple initiatives to oversee the architecture and lifecycle of enterprise AI systems, including agent identity, tool authorization, and secure development practices; to drive governance frameworks that define permitted AI use, contextual standards, and regulatory alignment — including GxP where applicable; and to ensure end-to-end observability and monitoring of AI agents in production.
- Own the operating model for AI enablement programs, including pilots, cohorts, and phased rollouts, and partner with Enablement/L&D teams to shape role‑based learning paths for AI builders
- Actively contribute to creating a more inclusive culture and environment at Moderna; endorse, create, and maintain antiracist policies and processes
Here's What You'll Need (Minimum Qualifications)
- Experience: 8+ years in Technical Program Management, Engineering Program Management, or similar roles in AI/ML-heavy environments
- Technical Depth: Strong understanding of AI/ML systems, including model training pipelines, LLMs, MLOps, data pipelines, and cloud infrastructure
- Strong understanding of AI/ML development workflows, AI‑assisted engineering tools, or modern software development platforms
- Demonstrated technical depth, problem-solving capabilities, and stakeholder and vendor management skills
- Experience in running programs within a cross-functional, global team of mixed engineering, architecture, and operations
- Ability to successfully scope and drive complex and multi-workstream programs in a structured, risk-considerate, data-driven fashion
- Experience improving developer productivity and building internal tools/platforms.
- Ability to define metrics, analyze tradeoffs, and drive decisions with data.
- Strong listener with the ability to deeply understand, ask the right questions, and proactively pursue constructive feedback
- Proven ability to operate in highly matrixed environments and influence without direct authority.
- Excellent written and verbal communication skills, including executive‑level storytelling
Here's What You'll Bring to the Table (Preferred Qualifications)
- Background in software engineering, data science, or machine learning
- Experience with LLM platforms, prompt engineering workflows, or AI copilots
- Experience with AI development platforms, copilots, developer tooling, or MLOps concepts
- Experience with responsible AI, model governance, or compliance frameworks
- Familiarity with tools such as Kubernetes, Airflow, MLFlow, or similar MLOps stacks
- Familiarity with governed enablement models (e.g., citizen development, platform standards, golden paths)
- Knowledge of security and compliance standards relevant to AI and AI-assisted engineering.
- Influential, inclusive, and trusted partner compassionate to the needs and situations of all your stakeholders
- Embrace a culture of continuous service improvement and service excellence
- A desire to make an impact as part of a high-growth, transformational company
- Experience with GxP environments and regulatory requirements
Pay & Benefits
At Moderna, we believe that when you feel your best, you can do your best work. That's why our US benefits and global well-being resources are designed to support you—at work, at home, and everywhere in between.
- Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs
- A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
- Family planning benefits, including fertility, adoption, and surrogacy support
- Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
- Savings and investment opportunities to help you plan for the future
- Location-specific perks and extras
The salary range for this role is $145,900.00 - $234,200.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual's position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.
About Moderna
Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.
By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.
We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.
If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Our Working Model
As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.
Moderna is a smoke-free, alcohol-free, and drug-free work environment.
Equal Opportunities
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!
Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.
Accommodations
We're focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.
Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an
$145.9k - $234.2k
The Role: Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management of AI-readiness initiatives at Moderna globally. We’re looking... ...Advance good infrastructure and security practices and culture Partner Collaboration -...SeniorPermanent employmentFull timeWork at officeLocal areaWork from home$100k - $150k
...An exciting opportunity within the Security Strategy and Governance (SSG) team whose... ...using technology, embrace automation and AI, and support Klaviyo's continued... ...organization. About the role: The Senior Technical Program Manager is an expert-level technical program...SeniorFlexible hours$90.1k - $209.5k
...Oracle's Global Physical Security (GPS) Systems Team is responsible... ...Physical Access and Identity Management (PIAM) technologies. We are seeking a seasoned The Technical Program Manager - Security Applications... ...life-saving care. And with AI embedded across our products...SuggestedContract workTemporary workFlexible hours$109.2k - $223.4k
...Cloud Infrastructure (OCI) is scaling at an unprecedented pace to support the next generation of AI-driven workloads. We are seeking a Senior Principal Technical Program Manager (TPM) to lead engagement and AI capacity buildout for large-scale enterprise customers ,...SeniorTemporary workFlexible hours$115.3k - $264.1k
...Job Description Manage the development and implementation process of a specific... ...monitor work of systems analysis and program staff, providing technical support and direction.Disclaimer:... ...innovations to life-saving care. And with AI embedded across our products and...SeniorTemporary workFlexible hours- ...solutions. Building the world's leading AI-powered, cloud-native products that... ...responsibilities About the Role As a Senior Technical Program Manager (TPM), you will be a key force-... ...Engineering, Product, Finance, and Security teams to ensure predictable delivery...SeniorShift work
$113k - $194k
...offered for eligible candidates. As a Sr. Technical Program Manager in our Personal Lines organization,... ...intersection of Product, Pricing, Data & AI, and Digital & Customer Experience.... ...tracking against established quality gates, security checkpoints, and compliance...SeniorFull timeWork at officeLocal areaRelocationRelocation packageFlexible hours- ...About LILT AI is changing how the world communicates — and... ...responsible for leading complex programs that provide the "fuel" for... .... You aren't just managing timelines; you are architecting... ...end execution of high-priority technical programs for frontier AI labs...SeniorLocal areaShift work
- ...About TetraScience TetraScience is the Scientific Data and AI Company building Tetra OS, the operating system for... ...you. Who You Are TetraScience is seeking an elite Technical Program Manager dedicated to a single, high-profile account in Cambridge, MA...SeniorWork experience placementImmediate start
$150k - $215k
...Senior Technical Program Manager WHOOP is on a mission to unlock human performance and healthspan. Our Health Machine Learning team develops the... ...technical context. You will also leverage and build AI-powered tools and workflows to increase the speed, visibility...SeniorFull timeWork at officeRelocation$193k - $220.3k
Senior Manager, Technical Program Manager AI / ML Are you interested in leading programs that deliver on critical... ...a great TPM can achieve. Our TPM Sr. Managers have: Strong technical backgrounds... ...with large cross-functional teams, secure commitments on deliverables, and...SeniorFull time$192k - $306k
...Senior / Principal Technical Program Manager, Life Sciences AI Cambridge, MA USA; San Francisco, CA USA Your Impact at LILA Lila is building a platform where AI and automation co-evolve to solve the hardest problems in medicine. Within Life Science AI (LSAI)...SeniorFull timeWork at officeLocal areaFlexible hours$115.3k - $264.1k
...delivery, and leverage emerging AI technologies to drive... ...complex, cross-functional programs from concept through... ...across engineering, product management, architecture, security, operations, and executive... ...programs. • Facilitate technical decision-making and architecture...SeniorTemporary workFlexible hours$109.2k - $223.4k
...Intelligence (HDI) is seeking a highly technical Senior Principal Technical Program Manager (IC5) to lead large-scale cloud... ..., architecture, product, security, operations, and executive leadership... ...innovations to life-saving care. And with AI embedded across our products and...SeniorTemporary workFlexible hours$79.9k - $166.1k
...Job Description Oracle Cloud Infrastructure (OCI) is seeking an AI native, self-starter and detail-oriented Technical Program Manager to join our dynamic and fast-paced data analytics team. As a Technical Program Manager at Oracle OCI, you will play a crucial role in...SeniorTemporary workFlexible hours$119.6k - $215.4k
...you thrive on driving complex technical programs from vision to reality? Are... ...the delivery of cutting-edge AI infrastructure? Join the Akamai... ...a Senior Technical Program Manager, you will require technical... ...Akamai to build, deliver, and secure their digital experiences helping...SeniorPermanent employmentWork experience placementWork at officeWork from homeWorldwideFlexible hoursShift work$116k - $145k
A leading cloud computing company is seeking a Senior Technical Program Manager. This role involves driving complex technical programs across engineering and product teams. The ideal candidate has over 5 years of program management experience in a technology environment...SeniorRemote job- Google Inc. is seeking a Technical Program Manager III for its Supply Chain and AI/ML Automation team. This role is essential for driving complex, multi-disciplinary projects that leverage innovations in AI. The ideal candidate will have a Bachelor's degree in a technical...Senior
$119.6k - $215.4k
Senior Technical Program Manager (Akamai Inference Cloud) United States (Remote) Job Description Do you... ...orchestrate the delivery of cutting‑edge AI infrastructure? Join the Akamai... ...worldwide choose Akamai to build, deliver, and secure their digital experiences helping...SeniorWork experience placementRemote workWorldwideShift work$112.5k - $202.5k
...working with innovative security products? Are you passionate about being a technical evangelist & growing... ...Senior Technical Account Manager, you will be responsible... ...without a glitch. AI : Enabling our customers... ...Akamai's FlexBase program is yet another way we show...SeniorWork experience placementWork at office$170k - $250k
...Sr. Technical Program Manager - Gemini Boston, MA USA Job Title: Senior Technical Program Manager Job Type: Full-time Job Location: Boston... ...and non-functional requirements (e.g. API payload vs API security). 4. Development ~ Align timelines, requirements...SeniorFull time$180k - $247.5k
...Technical Program Manager With its A.I.-powered robotic technology platform, Symbotic is changing the way consumer goods move through the supply... ...leader reimagining the supply chain with its end-to-end, AI-powered robotic and software platform. Symbotic reinvents the...SeniorContract workWork at office$124.9k - $146.1k
...is looking for a with experience managing Corporate Payments projects,... ...End-to-End Ownership: Drive technical implementation projects for Information Security project-related activities and initiatives... ...planning sessions, ensuring program increments align with business goals...SeniorFlexible hours$131.25k - $210k
...highly motivated and experienced Program Manager, Adoption & Enablement to... ...functionality, but also the technical concepts that underpin effective... ...50% Reports to : Sr. Director, RTO SaaS Delivery... ...information (bank details, Social Security Number) prematurely, please ignore...SeniorWork experience placement$145.9k - $234.2k
...document clear business and technical requirements, translating them... ...Engineering teams. Lead end‑to‑end program planning and execution for... ...‑functional initiatives, managing scope, schedules, dependencies... ...among Product, Engineering, Security, Compliance, and Business teams...Senior$150k - $206.8k
...seeking a highly motivated Senior IT Technical Program Manager with strong experience leading large... ...with cross-functional leaders across IT, security, infrastructure, applications, data,... ...the supply chain with its end-to-end, AI-powered robotic and software platform....Senior$156k - $208k
...Materials Technical Program Manager Cambridge, MA USA Your Impact at LILA Lila Sciences is applying its autonomous science platform to some... .... We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds...Full timeWork at officeLocal areaFlexible hours$167.28k - $196.8k
...fully supported. The Security team’s goal is to identify, measure, manage, mitigate, and report risk... ...and data safe. As a Program Manager in the Security... ..., Program Managers, and Technical Program Managers who work... ...programs by leveraging AI tools, automation, and retrospectives...Temporary workLocal area$166k - $220k
...Technical Program Manager Anduril Industries is a defense technology company with a mission to transform... ...systems is powered by Lattice OS, an AI-powered operating system that turns... ...maintain an active U.S. Top Secret security clearance Preferred Qualifications...Full timeContract workWork experience placementImmediate startWorldwide$167.28k - $196.8k
...on deck, working together to scale in a secure, decentralized, easy-to-use way. At... ...everyone. We are looking for a strong *Technical Program Manager *to join the Base team with emphasis in... ...ability to responsibly use generative AI tools and copilots (e.g., LibreChat,...Local area
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Sr. Technical Program Manager, AI Security. Be the first to apply!
- sr technical product manager Cambridge, MA
- senior technical manager Cambridge, MA
- technical superintendent Cambridge, MA
- technical supervisor Cambridge, MA
- technical program manager Cambridge, MA
- technical director Cambridge, MA
- technical manager Cambridge, MA
- technical writing manager Cambridge, MA
- technical services manager Cambridge, MA
- senior technical product manager Cambridge, MA

