Automation Service Engineering Associate II, Prenatal

A Rare Opportunity to Shape the Future of Genomics

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

BillionToOne is seeking an Automation Service Engineering Associate II to support high-throughput clinical patient testing in our CLIA-certified laboratory. This role provides primary service response for laboratory operations at our Union City site, including troubleshooting, repair, and maintenance of laboratory equipment and automation. The role will also contribute to cross-functional initiatives aimed at improving reliability, throughput, and quality. The ideal candidate excels at customer service, resolves issues with laboratory automation, and maintains thorough, compliant documentation. This is an on-site role supporting critical clinical operations; occasional off-hours support may be required.

Shift Hours: Tuesday-Saturday, 3pm-11:30pm (+PM Shift Differential)

Austin Expansion Update:
We are building a brand-new state-of-the-art laboratory in Austin, Texas , expected to launch in late 2027 / early 2028 , and we are looking for talented laboratory professionals who want to be part of this journey from the very beginning.

Candidates hired into this role will initially relocate to the Bay Area (Union City, CA) to train and work alongside our experienced laboratory teams. During this time (up to ~18 months), you will gain deep hands-on experience with BillionToOne's cutting-edge molecular diagnostic workflows, quality systems, and laboratory operations before transitioning to our new Austin facility once it opens.

This is a unique opportunity to gain hands-on training with our experienced lab teams and become one of the founding members of our Austin laboratory.

Responsibilities:

• Provide first-line service response for automated processes and instrumentation across the Union City facility.
• Execute and/or coordinate routine preventive maintenance for laboratory instruments and automation systems.
• Perform equipment qualifications, including Installation (IQ), Operational (OQ), and Performance Qualification (PQ).
• Troubleshoot and triage equipment issues; coordinate vendor support and escalations as needed.
• Draft and revise documentation related to equipment operation, maintenance, and troubleshooting.
• Maintain organized spare parts inventory and comprehensive, GDP-compliant service records.
• Identify, propose, and help implement process improvements; support testing and validation plans.
• Participate in special projects and cross-functional initiatives as assigned.

Qualifications:

• Bachelor's degree in a scientific or engineering discipline.
• 1+ year of hands-on experience servicing liquid handlers, or 2+ years in a technical service role (biotech, medical devices, clinical lab, or related).
• Familiarity with coding basics and flow control logic used in automation workflows.
• Understanding of clinical laboratory assays and their applications.
• Demonstrated ability to identify, analyze, and solve problems with minimal direction.
• Ability to interpret data to prioritize work and guide troubleshooting.
• Excellent documentation skills and working knowledge of Good Documentation Practices (GDP).
• Strong customer service orientation and effective verbal and written communication.
• Proven ability to work collaboratively and build strong cross-functional relationships.
• High attention to detail, accuracy, initiative, and self-motivation.
• Capacity and willingness to learn in a complex, fast-paced laboratory environment.

Nice-to-Haves:

• Experience troubleshooting liquid handler scripts and/or programming for laboratory automation.
• Experience with general programming or scripting languages.
• Experience working in a CLIA-regulated clinical laboratory environment.
• Experience developing and delivering training programs and conducting knowledge transfer.

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $83,781 per year, including a base pay rate of $31.48 - $32.36 per hour.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

For more information about how we protect your information, we encourage you to review our Privacy Policy.

BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA,a breakthrough that has already transformed the lives of over half a million patients worldwide.
Our Impact

Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample.
Unity Confirm™ enables non-invasive confirmation for high-risk screening results through the capture of intact circulating fetal cells using BillionToOne's Fetal Cell Capture™ Technology.
Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.
Our Growth

From $0 to $150M+ in Annual Recurring Revenue in just five years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.
Our Recognition

Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified , with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.
Our Future

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.

Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com