Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Scientist, Protein Design & In Vitro Selection

Moderna

A prominent biopharmaceutical firm in Cambridge is looking for a scientific leader to provide technical oversight in in vitro selection and cell-surface screening for viral and bacterial antigens. Candidates should have a PhD and at least 5 years of relevant industry experience, particularly in high-throughput screening and mammalian display systems. This role offers a unique opportunity to shape discovery capabilities and drive innovation within a dynamic team focused on advancing cutting-edge therapeutics. #J-18808-Ljbffr Moderna

Vacancy posted 4 days ago
Similar jobs that could be interesting for youBased on the Principal Scientist, Protein Design & In Vitro Selection in Cambridge, MA vacancy
  • $142.5k - $256.5k

     ...seeking a candidate to support protein design for vaccines and biologics...  ...that are validated in vitro and in vivo. The candidate...  ...partnership with in vitro selection and screening teams. You will...  ...in vivo mRNA delivery. As a Principal Scientist, you will also help shape design... 
    Principal

    Initial Therapeutics, Inc.

    Cambridge, MA
    5 days ago
  • $142.5k - $256.5k

     ...technical leadership for in vitro selection and cell-surface...  ...role will lead the design, execution, and continuous...  ...with computational protein design teams to...  ...role is intended for a scientist ready to own and evolve...  ...consistent with a Principal Scientist role.**Here... 
    Principal
    Work at office
    Work from home

    Moderna

    Cambridge, MA
    4 days ago
  • $142.5k - $256.5k

    The Role Moderna is seeking a Principal Scientist to support the AI‑enabled design of de novo antibodies and binder modalities...  ...role for an experienced protein designer who can build and...  ...Director, Computational Design and In Vitro Selection, and will also work closely with... 
    Principal
    Permanent employment

    Initial Therapeutics, Inc.

    Cambridge, MA
    5 days ago
  • $181.01k - $200.07k

     ...delivering on the promise of targeted protein degradation science to create...  ...® platform to efficiently design and optimize small-molecule...  ...Hit ID through candidate selection, including optimizing degraders...  ...(DMPK) colleagues on the in vitro and in vivo optimization of... 
    Principal
    Contract work

    C4 Therapeutics Inc

    Watertown, MA
    4 days ago
  • $166.77k - $202.09k

     ...an experienced, creative, and highly collaborative scientist to join our Biotherapeutics Computational Design team. In this role, you will build and deploy...  ...models for biologics design: develop methods for protein structure modeling, binder design, affinity/specificity... 
    Principal
    Full time
    Temporary work

    Bristol Myers Squibb

    Cambridge, MA
    1 day ago
  •  ...Inc. in Cambridge, Massachusetts, is looking for a Principal or Senior Principal Scientist to lead protein drug discovery for next-generation biologics. This...  ...driving programs from idea through lead‑candidate selection. The ideal candidate should possess a PhD in a relevant... 
    Principal

    Zealand Pharma U.S., Inc.

    Cambridge, MA
    4 days ago
  • $220k - $270k

    Principal or Senior Principal Scientist - Protein Drug Discovery Lead protein drug discovery for next‑generation biologics...  ...discovery through lead‑candidate selection. The role is part of the new...  ...and structure‑informed design across multiple formats (mAbs, bispecifics... 
    Principal

    Zealand Pharma U.S., Inc.

    Cambridge, MA
    4 days ago
  •  ...engineering cells inside the body using AI-designed, selective mRNA and targeted LNP technology. By...  ...Kernal seeks a highly motivated principal scientist for antibody development and...  ...development and/or production of recombinant proteins, monoclonal antibodies, and/or... 
    Principal
    Flexible hours

    Mass Digital Health

    Boston, MA
    3 days ago
  • $106k - $176.6k

     ...cardiovascular diseases. As a member of the In Vitro Pharmacology team, you will be playing a...  ...in GPCRs, enzymes, and other target protein classes. In addition, you will contribute...  ...throughput. Independently conceptualize, design and conduct in‑vitro studies aimed at... 
    Principal
    Permanent employment
    H1b
    Local area
    Worldwide
    Visa sponsorship
    Work visa
    Relocation package

    Pfizer Belgium

    Cambridge, MA
    3 days ago
  •  ...machine, and nature’s intelligence -- which we call Polyintelligence. Pioneering Intelligence is seeking a Principal Scientist – Computational Protein Design to serve as the technical lead on computational antibody design efforts pushing the forefront of AI-based antibody... 
    Principal

    Flagship Pioneering, Inc.

    Cambridge, MA
    more than 2 months ago
  • $165k - $200k

     ...modulating intracellular proteins that have...  ...? We are seeking a Principal Scientist with deep expertise in...  ...depot formulations) Design and optimize dosage forms...  ...interpret biorelevant in vitro and in vivo studies...  ...PK/PD and candidate selection Contribute to CMC... 
    Principal
    Shift work

    Parabilis Medicines

    Cambridge, MA
    25 days ago
  • $74k - $118.4k

    Moderna is seeking a Senior Research Associate to join its Protein Design team in Cambridge, MA. This role involves supporting protein expression screening and characterization crucial for vaccine development. Responsibilities include using mammalian cell culture techniques... 

    Moderna

    Cambridge, MA
    4 days ago
  • $146k - $209k

    A biotechnology company in Boston is seeking a Senior Scientist in Computational Protein Design to drive innovative computational design and optimization of synthetic proteins. The ideal candidate should possess a PhD and deep experience in de novo protein design and binding... 

    Flagship Pioneering

    Boston, MA
    5 days ago
  • $126k - $181.5k

    Flagship Pioneering is seeking a Senior Scientist in Molecular Biology to design next-generation DNA constructs. The role involves developing proteins, designing complex DNA libraries, and managing workflows for high-throughput screening. Ideal candidates will have a PhD... 

    Flagship Pioneering

    Cambridge, MA
    4 days ago
  •  ...ROLE We’re looking to hire a Principal Scientist in Bioengineering or Biology...  ..., including peptides and proteins, for topical and non‑topical...  ...nomination, validation and selection for anti‑aging or other skin...  ...experience: Pre‑clinical in‑vitro testing within dermatology and... 
    Principal
    Work at office
    Shift work

    Oddity Labs, Llc.

    Cambridge, MA
    4 days ago
  • Position Overview The Principal Machine Learning Scientist II will advance deep learning methods for biologics discovery at AbbVie. This individual...  ...- and structure-based deep learning models for protein and antibody design with emphasis on adapting them to the constraints... 
    Principal
    Work at office
    Local area
    Relocation
    3 days per week

    Allergan

    Cambridge, MA
    5 days ago
  • $115.5k - $192.5k

     ...Find out more: Our approach to R&D The Protein Biochemistry team at the GSK Vaccines R...  ...disease‑related initiatives. As a Principal Scientist, you will provide deep subject‑matter expertise...  ...solutions, contribute to workflow design and method development, and ensure experimental... 
    Principal
    Local area

    GlaxoSmithKline

    Cambridge, MA
    1 day ago
  • $146k - $209k

    Senior Scientist, Computational Protein Design Boston, MA USA About Abiologics Abiologics is a Flagship Pioneering company developing Synteins™ — a transformative class of fully synthetic proteins composed entirely of artificial building blocks such as D-amino acids and... 

    Flagship Pioneering

    Boston, MA
    5 days ago
  • $145.5k - $218.3k

    Manufacturing Science and Technology Principal Scientist page is loaded## Manufacturing Science and...  ..., Quality and R&D of Vertex on the design of processes and technologies required...  ...remotely up to two days per week; **or select** 2. **On-Site**: work five days per week... 
    Principal
    Contract work
    Summer work
    Remote work
    Flexible hours
    2 days per week

    Vertex Pharmaceuticals

    Boston, MA
    3 days ago
  •  ...AbbVie is seeking a Senior Scientist I with deep, hands-on...  ...role will involve designing and executing innovative...  ...Independently lead in vitro siRNA discovery...  ...orthogonal readouts (protein, functional, and transcriptomic...  ...go/no-go, lead selection, or optimization decisions... 
    Temporary work
    Local area

    AbbVie

    Cambridge, MA
    15 days ago
  • $148.21k - $179.6k

    Senior Scientist, Computational Sciences - Computational Antibody Discovery and Design Location: Cambridge Crossing - MA #LI-Hybrid...  ...sequencing and selection NGS data (such as in vitro display or in vivo immunization...  ...sequence data such as protein language models, structure... 
    Hourly pay
    Full time
    Temporary work
    Part time
    Summer work
    Remote work
    Flexible hours
    Shift work

    Bristol Myers Squibb

    Cambridge, MA
    5 days ago
  • Scientist - Protein Expression (Full-Time) Location: Cambridge, MA (On-site) Company: Anthology Bio Company summary Anthology is Boston-based genome design company. We engineer fungi through advanced genetics, microfluidics, and AI to biomanufacture functional proteins... 
    Full time
    Immediate start

    Anthology

    Cambridge, MA
    4 days ago
  • Scientist, Protein Production and Screening Join to apply for the Scientist, Protein Production and Screening role at GSK Scientist, Protein...  ...structural biology, protein biochemistry, and computational tools to design vaccine antigens, RNAs, delivery systems, and formulations... 
    Full time
    Local area

    GlaxoSmithKline

    Cambridge, MA
    4 days ago
  • Allergan is seeking a Principal Machine Learning Scientist II based in Cambridge, MA to advance deep learning methods for biologics discovery and therapeutic antibody design. This role involves collaborating with antibody engineers and computational biologists, focusing... 
    Principal

    Allergan

    Cambridge, MA
    5 days ago
  • Lancesoft is seeking a Principal Scientist in Cambridge, MA to lead the development of scalable, cell-based assay platforms for mRNA vaccine constructs. The role requires a PhD in a relevant field along with substantial experience in flow cytometry and microscopy-based... 
    Principal
    Contract work

    Lancesoft

    Cambridge, MA
    1 day ago
  • A biotechnology firm is seeking an AI/ML Scientist to enhance their models for protein therapeutic design in San Francisco or Boston. The role involves advancing model training with proprietary experimental data and requires experience in deep learning frameworks like... 

    Manifold Bio

    Boston, MA
    2 days ago
  • $220k - $270k

    Principal or Senior Principal Scientist - Peptide & Bioconjugate Drug Discovery Does it excite...  ...through lead‑candidate selection, partnering closely with...  ...computational chemistry, protein engineering, biology,...  ...Deep expertise in peptide design, solid‑phase peptide synthesis... 
    Principal

    Zealand Pharma U.S., Inc.

    Cambridge, MA
    4 days ago
  • $170k - $190k

     ...Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit...  ...manufacture of next-generation therapeutics. We are seeking a Principal Scientist to join our Biologics Cell Line Development team in Boston,... 
    Principal

    Asimov

    Boston, MA
    2 days ago
  • $122.25k - $176.58k

    Job Title and Location Principal Scientist, Neurology Research - Cambridge, MA About the...  ...single‑cell, spatial omics (RNA, protein, lipids), fluid proteogenomics (...  ...progression; refine patient selection criteria for future trial designs. Champion the "Everyday AI" initiative... 
    Principal
    Shift work

    Sanofi

    Cambridge, MA
    2 days ago
  • Bristol Myers Squibb is looking for an experienced scientist to join their Biotherapeutics Computational Design team in Cambridge. The role focuses on utilizing machine learning and structure-based methods to enhance biologics discovery and supports the development of... 

    Bristol Myers Squibb

    Cambridge, MA
    1 day ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Scientist, Protein Design & In Vitro Selection. Be the first to apply!