Senior Director, Portfolio Insights and Analytics

The Position

The Opportunity

The Senior Director of Portfolio Insights & Analytics (IA) serves as a key strategic partner and advisor to senior executive leadership, shaping commercial strategy, resource allocation, and portfolio investment prioritization. This role leads the enterprise portfolio analytics engine while acting as the champion and lead for cross-functional technical Centers of Excellence (COEs) across Forecasting, Analytics, Primary Market Research, and Competitive Intelligence.

We are seeking a high-caliber pharmaceutical insights leader who combines deep expertise in pharmaceutical data analytics, real-world evidence modeling, measurement, and long-range forecasting with powerful executive presence and the ability to influence without authority. The ideal candidate will elevate how data-driven evidence guides portfolio-level decisions, set enterprise standards for analytical rigor, and serve as a strategic voice on portfolio performance, market dynamics, and growth opportunities. This position reports to the Executive Director, Portfolio Insights & Analytics.

Key Responsibilities

Strategic Portfolio Analytics & Leadership

• Lead comprehensive portfolio analytics workstreams to inform long-range strategy, portfolio reviews, launch excellence, commercial baseline and strategic investment prioritization across therapeutic areas.
• Serve as a trusted strategic advisor to senior commercial and cross-functional executives, translating complex market, competitive, and internal performance data into actionable business options, trade-off assessments, and risk frameworks.
• Lead the integration of local, national, and global market drivers—including epidemiology, pricing/reimbursement, access dynamics, customer behavioral insights, competitive insights, and sub-national trends—into cohesive and actionable strategic insights.
• Leads portfolio demand forecasting in support of supply chain planning. Leads DDA coordination and execution of annual forecasting processes.

Technical Excellence & COE Leadership

• Champion cross-functional IA Centers of Excellence (COEs) across Forecasting, Customer Insight, and Competitive Intelligence, fostering technical excellence, consistency, and best-in-class methodologies across Insights & Analytics.
• Direct the design, implementation, and continuous evolution of enterprise measurement capabilities, including Marketing Mix Modeling (MMx), ROI assessments, predictive analytics, and scenario planning.
• Establish enterprise-wide standards for analytical rigor, data synthesis, and high-impact executive storytelling.
• Collaborates with brand analytics team and Product Suite teams to inform the prioritization and development of portfolio insight products and tools.
• Ensures compliance with all analytical, insights, and research methodologies across DDA, including training and reporting.

Team Building & Organizational Capability

• Build, mentor, and inspire a high-performing, inclusive team of insights and analytics professionals, establishing strong talent pipelines and driving a culture of continuous learning and innovation.
• Models inclusive, collaborative leadership, creating space for diverse perspectives and empowering others to contribute their best work.
• Establish effective operating models, engagement frameworks, and prioritization processes to support stakeholders across the organization.

Who you are

• You have a Bachelor’s degree in a scientific or quantitative discipline is preferred (e.g. Engineering, Life Sciences, Mathematics, Statistics, Economics, Data Science, etc).
• You have 12+ years of progressive leadership within the pharmaceutical or biotech industry, focusing on forecasting, commercial analytics, investment prioritization, and strategic planning.
• Technical Mastery: Deep hands-on and strategic understanding of pharmaceutical data ecosystems (claims, specialty pharmacy, EMR, promotional datasets) and advanced analytical frameworks (e.g., MMx, forecasting, market research synthesis). Deep knowledge of analytical approaches in the biopharmaceutical industry, including commercial forecasting, descriptive and predictive analytics, competitive intelligence, quantitative and qualitative market research, and commercial measurement methodologies, with a proven ability to modernize capabilities through innovative, AI-enabled solutions.
• Business Expertise: Must demonstrate a strong understanding of the pharmaceutical commercial value chain and market drivers, capable of contributing directly to strategic business planning beyond just data.
• Executive Presence & Influence: Proven ability to synthesize complex data into concise, strategic narratives for executive leadership, with demonstrated success influencing business strategy without direct authority.
• Cross-Functional Leadership: Demonstrated track record of establishing and scaling COEs or capability-building frameworks in partnership with commercial, medical, IT, and vendor teams.
• Strategic Acumen: Excellent ability to navigate ambiguity, prioritize high-value opportunities, and balance long-term strategic vision with short-term operational execution.
• Digital-first Mindset: Ability to look for opportunities to streamline and improve the customer experience and performance through digital tools, data and automation to create better, faster and more scalable outcomes.
• Drive for Results: Resourcefulness and decisiveness, with the ability to remain proactive and prioritize effectively in a fast-growing organization.

Location

• This role is based in South San Francisco and offers a hybrid schedule working 3 day per week on campus
• Relocation benefits are NOT available for this posting

The expected salary range for this position based on the primary location of South San Francisco, CA is $209,100/yr to $388,400/yr. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Benefits

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Genentech is an equal opportunity employer.

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