Director, Infection Prevention

Join the transformative team at City of Hope , where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope's growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.


The Director of Infection Prevention provides strategic and operational leadership for the Infection Prevention and Control (IPC) program across the organization. This leader ensures regulatory compliance, reduces healthcare-associated infections, and proactively mitigates infectious disease risks. You will play a critical role in driving a culture of safety while leading surveillance, outbreak response, education initiatives, and system-wide infection prevention strategies.


As a successful candidate, you will:

• Lead the development and execution of a comprehensive Infection Prevention and Control program aligned with organizational goals
• Drive measurable reductions in healthcare-associated infections including CLABSI, CAUTI, SSI, and C. difficile
• Oversee infection prevention teams and present key data and trends to executive leadership and stakeholders
• Direct surveillance activities, analyze infection data, and lead outbreak investigations and response strategies
• Ensure compliance with CDC, CMS, Joint Commission, and state regulatory requirements
• Serve as the subject matter expert for emerging infectious diseases and organizational response planning
• Partner with Pharmacy and Infectious Disease teams to advance antimicrobial stewardship initiatives
• Oversee infection control practices related to construction, environment of care, and risk mitigation
• Develop and lead education programs to promote infection prevention best practices across clinical and non-clinical teams
• Collaborate across departments to strengthen communication, compliance, and patient safety outcomes

• Master's degree in Nursing OR BSN with a master's in a related field (or equivalent experience)
• 5+ years of infection prevention experience
• 5+ years of leadership or management experience
• Experience with NHSN reporting and regulatory survey readiness
• Acute care experience required; multi-site or health system experience preferred
• Active California RN license and Certification in Infection Control (CIC) required
• Strong knowledge of regulatory standards (CDC, CMS, Joint Commission, Title 22)
• Demonstrated expertise in data analysis, infection surveillance, and performance improvement
• Excellent communication, leadership, and cross-functional collaboration skills