Chief Commercial Officer

About Summit:

Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people. Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence.

Summit’s team is inspired to touch and help change lives through Summit’s clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including:

Non-small Cell Lung Cancer (NSCLC)

• HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI.

• HARMONi-3: Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.

• HARMONi-7: Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.

Colorectal Cancer (CRC)

• HARMONi-GI3: Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy.

Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.

Overview of Role:

The Chief Commercial Officer (CCO) will be a key member of the executive leadership team, responsible for 
developing and executing the company's commercial strategy. This role will oversee all aspects of 
commercialization, including market access, sales, marketing, and distribution. The CCO will work closely with 
cross-functional teams to ensure successful product launches and sustainable growth in global markets.

Role and Responsibilities:

• Develop and execute a comprehensive commercial strategy for ivonescimab and drive the successful 
  launch and growth of the company's products in global markets
• Lead market access strategies, including pricing, reimbursement, and health economics, to ensure 
  optimal market penetration and patient access
• Build and lead high-performing sales and marketing teams, establishing clear goals, performance 
  metrics, and incentive programs that align with the Company’s values and strategic deliverables
• Oversee the planning and execution of product launches, ensuring alignment with regulatory 
  requirements and market needs
• Identify and pursue strategic partnerships, alliances, and licensing opportunities to expand the 
  company's commercial footprint
• Foster strong relationships with key stakeholders, including healthcare providers, payers, and patient 
  advocacy groups
• Develop and manage the commercial budget, ensuring efficient allocation of resources to achieve 
  commercial objectives
• Monitor market trends, competitive landscape, and customer insights to inform strategic decisionmaking and identify growth opportunities
• Ensure all commercial activities comply with relevant regulations and industry standards
• All other duties as assigned

Experience, Education and Specialized Knowledge and Skills:

• Bachelor’s degree in business, Marketing, Life Sciences, or a related field; MBA or advanced degree 
  preferred
• Minimum of 15+ years of experience in commercial leadership roles within the pharmaceutical or 
  biotechnology industry, with direct experience in NSCLC/NDCLC and solid tumors
• Experience with blockbuster drug commercial launches in NSCLC/NDCLC and/or solid tumors within 
  the past 5 years
• Proven track record of successfully launching and commercializing pharmaceutical products in global 
  markets
• Strong strategic thinking and analytical skills, with the ability to translate market insights into 
  actionable strategies
• Excellent leadership and team-building skills, with a demonstrated ability to inspire and motivate crossfunctional teams
• Exceptional communication and interpersonal skills, with the ability to build and maintain relationships
  with key stakeholders
• In-depth knowledge of market access, pricing, reimbursement, and health economics.
• Experience in business development and strategic partnerships
• Ability to thrive in a fast-paced, dynamic environment and adapt to changing market conditions
• Travel up to 50%

This is the pay for this position

Pay Transparency

$400,000—$480,000 USD

Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.

Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at  View email address on job-boards.greenhouse.io to obtain prior written authorization before referring any candidates to Summit.

Summit Therapeutics Inc. is an Equal Opportunity Employer and takes pride in creating and maintaining diverse environment. We do not discriminate in recruitment, hiring, training or promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.