Senior Medical Science Liaison - East

The mission of Neurogene is to treat devastating neurological diseases to improve the lives of patients and families impacted by these rare diseases. Neurogene is developing novel approaches and treatments to address the limitations of conventional gene therapy in central nervous system disorders. This includes selecting a delivery approach to maximize distribution to target tissues and designing products to maximize potency and purity for an optimized efficacy and safety profile. The Company’s novel and proprietary EXACT transgene regulation platform technology allows for the delivery of therapeutic levels while limiting transgene toxicity associated with conventional gene therapy. Neurogene has constructed a state‑of‑the‑art gene therapy manufacturing facility in Houston, Texas. CGMP production of NGN-401 was conducted in this facility and will support pivotal clinical development activities. This transformative work is driven by our highly collaborative people who come together each day to bring us closer to achieving our mission. As an employee of Neurogene, you will be part of building a culture that honors patient and caregiver mindsets and nurtures innovation, creative problem solving and a strong sense of purpose. Position Overview Reside within the assigned territory (US East) and ability to travel is required to engage with KOLs, attend medical congresses, and attend HQ meetings up to 60% of the time. Remote (US East) with travel required. The Senior Medical Science Liaison (Senior MSL) – US East will function as a subject matter expert (SME) connection between Neurogene and key external stakeholders to support the advancement of the NGN-401 program in Rett syndrome and to conduct bi‑directional scientific exchange. The Senior MSL will be instrumental in developing strong relationships with Clinical and Scientific Key Opinion Leaders (KOLs) to source actionable field medical insights and help guide internal decision making. The Senior MSL will also be required to build robust relationships with internal stakeholders and provide medical support for a variety of initiatives across the organization. The Senior MSL will provide strategic and operational support for executing field medical tactics as well as ongoing territory planning, analysis, and development. The strategic areas of focus include scientific exchange, health‑care decision maker education, and evidence generation. Additionally, this Senior MSL position is unique in that they will have the opportunity to engage in HQ‑based projects and initiatives (e.g. content development, advisory board planning). The ideal candidate will be an experienced Medical Affairs professional who is intrinsically motivated, has a collaborative spirit, and has experience working in pediatric neurology, neurodevelopmental disorders, rare disease, genetics, or gene therapy/genetic medicine. Accountabilities and Responsibilities Establish, build, and maintain collaborative relationships with subject matter experts, investigators, institutions, and other key external stakeholders by providing disease state education and communicating the value of NGN-401 for Rett syndrome. Engage in peer‑to‑peer scientific exchange of complex medical and scientific information with disease state experts. Present scientifically rigorous value‑based information to payer stakeholders. Present medical/scientific medical education to internal and external groups that are tailored to the specific audience. Develop and cultivate relationships with cross‑functional partners. Work closely with HQ Clinical/Medical to efficiently respond to questions from the field. Gather medical insights that help to inform corporate strategy and clinical/medical initiatives. Build and manage Congress and KOL engagement plans. Represent Neurogene at relevant medical/scientific conferences and meetings. Keep abreast of current and emerging data as it relates to Neurogene’s areas of focus and share learnings from other neurodevelopmental/gene therapy/genetic medicine programs to help inform Neurogene’s planning and development. Education Advanced degree (PharmD, PhD, DNP, MD, DO) or Master’s Level Certified Genetic Counselor (CGC) Experience Minimum of 6 years’ experience in the biopharmaceutical industry with at least 4 years’ experience as an MSL required. Experience working in translational/clinical development is a plus. Experience and comfort working on special projects including Medical Information, Publications, and Advisory Boards required. Experience in CNS/neurology, gene therapy/genetic medicine, and rare disease strongly preferred. Experience in neurodevelopmental disorders with relevant KOL relationships is a plus. Product launch experience is a plus. Knowledge, Skills and Attributes Ability to understand and articulate complex medical and scientific information to internal and external stakeholders and tailor information for a specific audience. Outstanding presentation, written, and oral communication skills. Ability to identify, cultivate and maintain key external relationships with key stakeholders. Ability to inform and influence key external stakeholders through educational initiatives and scientific exchange. Ability to demonstrate the impact and value of Field Medical Affairs to the organization. Ability to manage competing priorities and projects. Ability to prioritize and manage expectations while analyzing complex issues. Thrive in a fast‑paced innovative environment while remaining agile and adaptive. Ability to maintain the highest degree of confidentiality and integrity; uphold the company’s high ethics and professionalism. Adhere to corporate policies in all activities, including those related to clinical trials, scientific interactions with internal and external groups, and unsolicited requests for medical/scientific information. Continuous, strong focus on delivering results in a performance‑based culture. Ability to track and measure performance against defined metrics. Self‑starter with high degree of energy, independence, initiative, and self‑motivation, as illustrated by the ability to instill a sense of pace and urgency into the team. Someone who moves fast and decisively in a balanced manner, with a passion for the growing company. Passionate, collaborative, creative, willing to take prudent risks, and motivated by the creation of a company focused on transformative treatments for patients and their families. This job description has been developed based upon the expected and current duties, responsibilities and requirements for the position. Because job requirements evolve with the changing needs of Neurogene’s business, this description is subject to change and may be modified at any time, whether formally or informally. Neurogene is an Equal Opportunity Employer and will assess all applicants based on their qualifications for the job, without regard to race, color, sex, religion, national origin, age, disability, sexual orientation, gender identity, protected veteran, disability status or any other characteristics protected by applicable federal, state or local law. #J-18808-Ljbffr Jimmy Jazz