Project Manager, Clinical Portfolio

Project Manager, Clinical Portfolio

Syneos Health® is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators at every point across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress.

Every day we perform better because of how we work together, as one team, each the best at what we do. We bring together talented experts across a broad spectrum of business critical corporate functions. Every role plays an essential part in enabling our customers to achieve their goals. Our teams are agile, collaborative, and committed to delivering—for each other, for our customers, and ultimately for the people who rely on the services we support.
Discover what your 25,000 future colleagues already know:

Why Syneos Health
• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to building an inclusive culture – where you can authentically be yourself. Central to this is our purpose – Driven to Deliver – which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone’s life.
• We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress. 

Job Responsibilities

Job Summary

The Project Manager is responsible for independently planning, managing and delivering assigned initiatives across the Clinical Future Operating Model Portfolio.

This role provides structured project management discipline across transformation, operating model and cross-functional clinical initiatives. The Project Manager owns delivery of agreed scope, timelines, milestones, Risk, Issues, Action and Decision Log (RAID), reporting and stakeholder coordination, working closely with Accountable Executives, business owners, workstream leads, Subject Matter Experts (SMEs) and enabling functions.

The role is expected to operate independently, drive accountability across workstreams, escalate decision-ready issues, and support initiatives from mobilisation through delivery, closure and transition to business ownership.

Core Responsibilities

1. Independently manage assigned clinical portfolio initiatives from mobilisation through delivery, closure and handover.

2. Develop and maintain project plans, milestones, RAID logs, action logs, decision logs and dependency trackers.

3. Drive day-to-day execution, ensuring workstreams remain aligned to scope, timelines, governance expectations and delivery commitments.

4. Lead project meetings, workstream check-ins and stakeholder forums to drive progress, resolve blockers and maintain accountability.

5. Coordinate cross-functional teams, including business owners, workstream leads, SMEs and enabling functions.

6. Define and maintain clear project scope, objectives, deliverables, roles, success measures and ownership.

7. Identify, manage, document, and escalate risks, issues, assumptions and dependencies in a timely and decision-ready manner.

8. Prepare executive summaries, project status updates and governance inputs.

9. Real-time maintenance of accurate and current project information in Smartsheet and agreed systems of record.

10. Partner with portfolio leadership to align risks, dependencies, escalations and decisions to governance requirements.

11. Drive delivery discipline through action tracking, milestone follow-up, decision management and escalation.

12. Support KPI and benefits tracking in partnership with the Value Realisation Office.

13. Partner with Business to embed change impact, readiness, learning, adoption and hyper care into delivery.

14. Support process mapping, RACI clarification, handoff identification and transition planning where required.

15. Ensure implementation and project closure activities are completed.

16. Manage confidentiality requirements for restricted or sensitive initiatives.

17. Contribute to continuous improvement of PM templates, Smartsheet toolkits, governance standards and ways of working.

18. Provide business flex PM support where structured project management capability is required.

19. Perform other work-related duties as assigned.

Additional Qualifications

• Experience independently managing projects, transformation initiatives or cross-functional delivery work.

• Strong project management skills across planning, execution, RAID, reporting and governance.

• Ability to work independently, drive delivery and manage multiple priorities.

• Strong organisation, attention to detail and stakeholder management skills.

• Ability to turn ambiguous business asks into clear plans, actions and ownership.

• Experience preparing executive summaries, governance materials or leadership reporting.

• Experience managing risks, issues, dependencies, decisions and escalations.

• Experience using project management, reporting or portfolio tools.

• Ability to influence and drive accountability across teams without direct authority. Understanding of change, readiness, adoption, training and implementation needs.

• Experience in healthcare, life sciences, clinical operations or consulting.

• Experience supporting transformation portfolios or PMO environments.

• Experience using Smartsheet or similar project / portfolio tools.

• Exposure to KPI tracking, benefits realization or value reporting.

• Experience with process mapping, RACI development or operating model change.

• Project management certification preferred.

US ONLY

Years of experience required

1-3 years or equivalent combined education and experience in life sciences, health sciences, or related field.

Physical Requirements: Position requires: ability to occasionally move about inside the office to access filing cabinets, office equipment, etc. and to move between office locations; ability to maintain a stationary position for prolonged periods of time; ability to occasionally manipulate (e.g., lift, carry, move) office

items and packages of light to medium weights of 10-35 pounds; ability to constantly operate a computer and other office productivity equipment (e.g., scanner, phone, printer, copier); ability to perceive and assess written materials for prolonged periods of time; and ability to frequently communicate with

colleagues on the phone, by email, and in-person. Work Environment: This job operates in a professional office environment. This role routinely uses standard office equipment such as computers, phones, photocopiers, and filing cabinets. The noise level in the work environment is low. This is a largely sedentary role.

At  Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.

Salary Range:

$80,600.00 - $145,000.00

The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role.

Get to know Syneos Health

Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.

No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.

Additional Information

Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.

Summary

JOB SUMMARY The Project Manager is responsible for independently planning, managing and delivering assigned initiatives across the Clinical Future Operating Model Portfolio. This role provides structured project management discipline across transformation, operating model and cross-functional clinical initiatives. The Project Manager owns delivery of agreed scope, timelines, milestones, Risk, Issues, Action and Decision Log (RAID), reporting and stakeholder coordination, working closely with Accountable Executives, business owners, workstream leads, Subject Matter Experts (SMEs) and enabling functions. The role is expected to operate independently, drive accountability across workstreams, escalate decision-ready issues, and support initiatives from mobilisation through delivery, closure and transition to business ownership.